Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Lai N, Chan"'
Autor:
Samiksha Samiksha, Lai N. Chan
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/2f6e363a04ed485c9465c9904dc0fc6b
Autor:
Mingli Li, Lu Yang, Anthony K. N. Chan, Sheela Pangeni Pokharel, Qiao Liu, Nicole Mattson, Xiaobao Xu, Wen‐Han Chang, Kazuya Miyashita, Priyanka Singh, Leisi Zhang, Maggie Li, Jun Wu, Jinhui Wang, Bryan Chen, Lai N. Chan, Jaewoong Lee, Xu Hannah Zhang, Steven T. Rosen, Markus Müschen, Jun Qi, Jianjun Chen, Kevin Hiom, Alexander J. R. Bishop, Chun‐Wei Chen
Publikováno v:
Advanced Science, Vol 10, Iss 17, Pp n/a-n/a (2023)
Abstract Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS). However, the epigenetic networks underlying the maintenance of oncogenic signaling and therapeutic response remain unclear. Using a series of epigenetics
Externí odkaz:
https://doaj.org/article/d8eb48a7527744de8eb5ea7136bf0bee
Autor:
Humberto Contreras-Trujillo, Jiya Eerdeng, Samir Akre, Du Jiang, Jorge Contreras, Basia Gala, Mary C. Vergel-Rodriguez, Yeachan Lee, Aparna Jorapur, Areen Andreasian, Lisa Harton, Charles S. Bramlett, Anna Nogalska, Gang Xiao, Jae-Woong Lee, Lai N. Chan, Markus Müschen, Akil A. Merchant, Rong Lu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
DNA barcoding is a promising technology for the simultaneous analysis of genetic and phenotypic heterogeneity. Here, the authors combine DNA barcoding and single-cell RNA-seq to study heterogeneity, progression and response to therapy in B-cell acute
Externí odkaz:
https://doaj.org/article/1cf0a0d2c96e4d41be8c44bd2d61e2d2
Autor:
Julia Hauer, Carolina Vicente-Dueñas, Arndt Borkhardt, Isidro Sánchez-García, Markus Müschen, Francisco J. García-Criado, Maria B. García-Cenador, Javier De Las Rivas, Diego Alonso-López, Alberto Orfao, Oscar Blanco, Sebastian Ginzel, Michael Gombert, Martin Dugas, Christoph Bartenhagen, Guillermo Rodríguez-Hernández, Inés González-Herrero, Idoia García-Ramírez, Lai N. Chan, Franziska Auer, Alberto Martín-Lorenzo
Supplementary Figure 1: Mouse generation and GSEA enrichment analysis of Sca1-BCR-ABLp190 mice. Supplementary Figure 2: Time course of the percentage of B220+ cells in PB of Sca1-BCR-ABLp190 and Sca1-BCR-ABLp190+Pax5+/- mice. Supplementary figure 3:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2888ec94c23b551c386ae8273b12e687
https://doi.org/10.1158/0008-5472.22420206.v1
https://doi.org/10.1158/0008-5472.22420206.v1
Autor:
Julia Hauer, Carolina Vicente-Dueñas, Arndt Borkhardt, Isidro Sánchez-García, Markus Müschen, Francisco J. García-Criado, Maria B. García-Cenador, Javier De Las Rivas, Diego Alonso-López, Alberto Orfao, Oscar Blanco, Sebastian Ginzel, Michael Gombert, Martin Dugas, Christoph Bartenhagen, Guillermo Rodríguez-Hernández, Inés González-Herrero, Idoia García-Ramírez, Lai N. Chan, Franziska Auer, Alberto Martín-Lorenzo
Differentially expressed genes in bone marrow tumors from Sca1-BCR-ABLp190 mice compared to wild-type B220+ bone marrow B cells. (3692 genes-probesets with FDR = 0.05)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6feede010b84fbf64b3ff8fdffa3684
https://doi.org/10.1158/0008-5472.22420200.v1
https://doi.org/10.1158/0008-5472.22420200.v1
Autor:
Julia Hauer, Carolina Vicente-Dueñas, Arndt Borkhardt, Isidro Sánchez-García, Markus Müschen, Francisco J. García-Criado, Maria B. García-Cenador, Javier De Las Rivas, Diego Alonso-López, Alberto Orfao, Oscar Blanco, Sebastian Ginzel, Michael Gombert, Martin Dugas, Christoph Bartenhagen, Guillermo Rodríguez-Hernández, Inés González-Herrero, Idoia García-Ramírez, Lai N. Chan, Franziska Auer, Alberto Martín-Lorenzo
Preleukemic clones carrying BCR-ABLp190 oncogenic lesions are found in neonatal cord blood, where the majority of preleukemic carriers do not convert into precursor B-cell acute lymphoblastic leukemia (pB-ALL). However, the critical question of how t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e76ecb70fdd268775761f2f288a9950
https://doi.org/10.1158/0008-5472.c.6510588.v1
https://doi.org/10.1158/0008-5472.c.6510588.v1
Autor:
Julia Hauer, Carolina Vicente-Dueñas, Arndt Borkhardt, Isidro Sánchez-García, Markus Müschen, Francisco J. García-Criado, Maria B. García-Cenador, Javier De Las Rivas, Diego Alonso-López, Alberto Orfao, Oscar Blanco, Sebastian Ginzel, Michael Gombert, Martin Dugas, Christoph Bartenhagen, Guillermo Rodríguez-Hernández, Inés González-Herrero, Idoia García-Ramírez, Lai N. Chan, Franziska Auer, Alberto Martín-Lorenzo
Supplementary Figures and Table legends as well as supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9543ca39a1f279c4283bf85756f0197d
https://doi.org/10.1158/0008-5472.22420203.v1
https://doi.org/10.1158/0008-5472.22420203.v1
Autor:
Kadriye Nehir Cosgun, Huda Jumaa, Mark E. Robinson, Klaus M. Kistner, Liang Xu, Gang Xiao, Lai N. Chan, Jaewoong Lee, Kohei Kume, Etienne Leveille, David Fonseca-Arce, Dhruv Khanduja, Han Leng Ng, Niklas Feldhahn, Joo Song, Wing-Chung Chan, Jianjun Chen, M. Mark Taketo, Shalin Kothari, Matthew S. Davids, Hilde Schjerven, Julia Jellusova, Markus Müschen
Publikováno v:
bioRxiv
In most cell types, nuclear β-catenin functions as prominent oncogenic driver and pairs with TCF7-family factors for transcriptionalactivationof MYC. Surprisingly, B-lymphoid malignancies not only lacked expression and activating lesions of β-caten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1f21543f9597e44be327c451d0a6a9
https://europepmc.org/articles/PMC10054980/
https://europepmc.org/articles/PMC10054980/
Autor:
Kohei Kume, Zhengshan Chen, Lai N. Chan, Mark E. Robinson, Etienne Leveille, Jaewoong Lee, Kadriye Nehir Cosgun, David Fonseca Arce, Dhruv Khanduja, Lars Klemm, Markus Müschen
Publikováno v:
Blood. 140:5900-5901
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92e21f9c5ad811764aee858edacb0eb1
https://doi.org/10.1182/blood-2022-170396
https://doi.org/10.1182/blood-2022-170396
Autor:
Kadriye Nehir Cosgun, Huda Jumaa, Mark E. Robinson, Lai N. Chan, Jaewoong Lee, Kohei Kume, David Fonseca Arce, Julia Jellusova, Markus Müschen
Publikováno v:
Blood. 140:3114-3115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec26a4e0a6e3e6449e12c66fe1a1f31a
https://doi.org/10.1182/blood-2022-169961
https://doi.org/10.1182/blood-2022-169961