Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Lai K. Leung"'
Publikováno v:
Toxicology Letters. 344:18-25
Recent findings have revealed that exposure to environmental contaminants may result in obesity and pose a health threat to the general public. As the activity of transient receptor potential channels (TRPs) plays a permissive role in adipogenesis, t
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135637 (2015)
High blood cholesterol has been associated with cardiovascular diseases. The enzyme HMG CoA reductase (HMGCR) is responsible for cholesterol synthesis, and inhibitors of this enzyme (statins) have been used clinically to control blood cholesterol. St
Externí odkaz:
https://doaj.org/article/8f01d1c1360c4a6281410a5d1355477b
Publikováno v:
Chemosphere. 253
Zeranol is an approved but controversial growth-promoting agent for livestock in North America. It is a mycotoxin metabolite secreted by the Fusarium family fungi. The regulatory bodies in this region have established the acceptable daily intake and
Publikováno v:
Journal of Pharmacy and Pharmacology. 70:1253-1261
Objectives Hypercholesterolaemia is a major risk factor for developing atherosclerosis. Increased consumption of fruits and vegetables is recommended to hypercholesterolaemic patients. In this study, the hypocholesterolaemic effect of apigenin and lu
Publikováno v:
Molecular and Cellular Endocrinology. 452:131-137
CYP19 is the single copy gene encoding for the estrogen synthetic enzyme aromatase. Alternate splicing of the promoter is the regulatory mechanism of this gene. In the brain, estrogen is synthesized in neuronal and glial cells and the gene is mainly
Publikováno v:
Chemosphere. 181:289-295
Polybrominated diphenyl ethers (PBDEs) are flame retardants generally employed in manufacturing household items. Surface water may remove and carry these chemicals to the drainage upon disposal of the items, and ultimately the chemicals enter our foo
Publikováno v:
Chemosphere. 174:499-505
Polybrominated diphenyl ethers (PBDEs) are chemicals used as flame retardants in household products. After disposing of these items, PBDEs leach from the products by surface water. BDE-47 is a PBDE congener commonly isolated from contaminated food an
Publikováno v:
Planta Medica. 81:S1-S381
Publikováno v:
Chemico-Biological Interactions. 260:84-90
Aflatoxins are fungal metabolites which pose a major threat to food safety. Although these mycotoxins are established hepatocarcinogens, their effect on the reproductive organ is unknown. Transient Receptor Potential Channels (TRPs) are ubiquitously
Publikováno v:
Environmental Toxicology and Pharmacology. 48:197-202
Studies have shown that corticotrophin-releasing hormone (CRH) and relaxin are associated with early delivery. Our lab previously has shown the mycotoxin zeranol increases placental CRH expression. The mycotoxin is used in the farming industry to pro