Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Lai Guan NG"'
Autor:
Gaofei Li, Yicong Sun, Immanuel Kwok, Liting Yang, Wanying Wen, Peixian Huang, Mei Wu, Jing Li, Zhibin Huang, Zhaoyuan Liu, Shuai He, Wan Peng, Jin-Xin Bei, Florent Ginhoux, Lai Guan Ng, Yiyue Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Eosinophils are a group of granulocytes well known for their capacity to protect the host from parasites and regulate immune function. Diverse biological roles for eosinophils have been increasingly identified, but the developmental pattern
Externí odkaz:
https://doaj.org/article/3fea63b6b24a49bba081a7c7051025dd
Autor:
Yumeng Cao, Jia Qi, Juan Wang, Liang Chen, Yuan Wang, Yijing Long, Boyu Li, Junliang Lai, Yejie Yao, Yiwen Meng, Xiaohua Yu, Xiao‐Dong Chen, Lai Guan Ng, Xinyu Li, Yao Lu, Xiaoyue Cheng, Wenguo Cui, Yun Sun
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract The prevalence of infertility caused by endometrial defects is steadily increasing, posing a significant challenge to women's reproductive health. In this study, injectable “homing‐like” bioactive decellularized extracellular matrix sh
Externí odkaz:
https://doaj.org/article/94d365ca0a9640f8bc7d1dc56ab855fa
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundChronic pruritus of unknown origin (CPUO) is poorly understood and lacks effective treatment options.ObjectivesWe aimed to elucidate abnormalities in the sweat apparatus of patients with CPUO, and to assess efficacy and safety of treatment
Externí odkaz:
https://doaj.org/article/3233f4fad8ab442191aef2bff0f7bdd6
Autor:
Guillaume Carissimo, Weili Xu, Immanuel Kwok, Mohammad Yazid Abdad, Yi-Hao Chan, Siew-Wai Fong, Kia Joo Puan, Cheryl Yi-Pin Lee, Nicholas Kim-Wah Yeo, Siti Naqiah Amrun, Rhonda Sin-Ling Chee, Wilson How, Stephrene Chan, Bingwen Eugene Fan, Anand Kumar Andiappan, Bernett Lee, Olaf Rötzschke, Barnaby Edward Young, Yee-Sin Leo, David Chien Lye, Laurent Renia, Lai Guan Ng, Anis Larbi, Lisa FP Ng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
COVID-19 severity is associated with cytokine levels and lymphopenia, but the role of immune cell subsets is not well understood. Here the authors immunophenotype whole blood samples from 54 COVID-19 patients and find that the immature neutrophil-to-
Externí odkaz:
https://doaj.org/article/d967340f6639442885027de8b53a2e43
Publikováno v:
Blood Science, Vol 2, Iss 2, Pp 41-43 (2020)
Externí odkaz:
https://doaj.org/article/a476295d29514d9cb301170445e498db
Autor:
Carla Claser, Samantha Yee Teng Nguee, Akhila Balachander, Shanshan Wu Howland, Etienne Becht, Bavani Gunasegaran, Siddesh V. Hartimath, Audrey W. Q. Lee, Jacqueline Theng Theng Ho, Chee Bing Ong, Evan W. Newell, Julian Goggi, Lai Guan Ng, Laurent Renia
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Severe malaria can be associated with respiratory complications. Here, the authors show that malaria-associated pulmonary vascular damage is a consequence of IFNγ-activated lung endothelial cells capturing, processing, and cross-presenting malaria p
Externí odkaz:
https://doaj.org/article/1fc2aedd388244a98e0a91adeebd988e
Autor:
Ai Kia Yip, Akhila Balachander, Leonard D.L. Tan, Ka Hang Liong, Rui Zhen Tan, Karl Balabanian, Francoise Bachelerie, Lai Guan Ng, Keng-Hwee Chiam
Publikováno v:
Blood Science, Vol 1, Iss 1, Pp 102-112 (2019)
Abstract. Neutrophils are essential immune cells that defend the host against pathogenic microbial agents. Neutrophils are produced in the bone marrow and are retained there through CXCR4–CXCL12 signaling. However, patients with the Warts, Hypogamm
Externí odkaz:
https://doaj.org/article/f7ea631e27c347a19d8317c0dc7d809c
Autor:
Jia Tong Loh, Thomas Jun Feng Lim, Kyoko Ikumi, Takuma Matoba, Baptiste Janela, Merry Gunawan, Tatsuya Toyama, Maegan Bunjamin, Lai Guan Ng, Michael Poidinger, Akimichi Morita, Florent Ginhoux, Sayuri Yamazaki, Kong-Peng Lam, I-hsin Su
Publikováno v:
iScience, Vol 10, Iss , Pp 23-39 (2018)
Summary: Ezh2, a well-established epigenetic repressor, can down-regulate leukocyte inflammatory responses, but its role in cutaneous health remains elusive. Here we demonstrate that Ezh2 controls cutaneous tolerance by regulating Langerhans cell (LC
Externí odkaz:
https://doaj.org/article/20cb73c3b3dc42908530f65184e738a4
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytes are a subset of cells that are categorized together with dendritic cells (DCs) and macrophages in the mononuclear phagocyte system (MPS). Despite sharing several phenotypic and functional characteristics with MPS cells, monocytes are unique
Externí odkaz:
https://doaj.org/article/41c2bd77b64c4484b721f4cfad88f6d9
Autor:
Jing Zhu, Jie Dong, Lu Ji, Peiyong Jiang, Ting Fan Leung, Dehua Liu, Lai Guan Ng, Miranda Sin-Man Tsang, Delong Jiao, Christopher Wai-Kei Lam, Chun-Kwok Wong
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
IL-1 family regulatory cytokine IL-37b can suppress innate immunity and inflammatory activity in inflammatory diseases. In this study, IL-37b showed remarkable in vitro suppression of inflammatory tumor necrosis factor-α, IL-1β, IL-6, CCL2, and CXC
Externí odkaz:
https://doaj.org/article/3a3d028b30e94d739034229324abd2bb