Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lai, Khai"'
Assessments of synaptic density in human brain are often based on measurements of synaptic proteins. Little information is available on their post-mortem stability. We have investigated this by ELISAs of the pre-synaptic proteins syntaxin and synapto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9c83fe3c815679c79b2d8ddf2ccfb4
https://ora.ox.ac.uk/objects/uuid:56f93f4f-1a29-4c38-8f2a-038575af42a1
https://ora.ox.ac.uk/objects/uuid:56f93f4f-1a29-4c38-8f2a-038575af42a1
Autor:
Audrey Riboulet-Chavey, Frédérique Diraison, Florence Susan Wong, Lai Khai Siew, Guy A. Rutter
Publikováno v:
Diabetes. 57:415-423
OBJECTIVE—Apoptotic destruction of insulin-producing pancreatic β-cells is involved in the etiology of both type 1 and type 2 diabetes. AMP-activated protein kinase (AMPK) is a sensor of cellular energy charge whose sustained activation has recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d983c29cd52e676aecd86680d5d9492
https://doi.org/10.2337/db07-0993
https://doi.org/10.2337/db07-0993
Autor:
Peter Easton, Joanne Boldison, Stephanie J. Hanna, Lai Khai Siew, James A. Pearson, Adrian Tsui, Li Wen, Terri C. Thayer, Sartaj Ahmed, F. Susan Wong, Evy De Leenheer, Joanne Davies
Publikováno v:
Diabetes. 65(11)
Low-avidity autoreactive CD8 T cells (CTLs) escape from thymic negative selection, and peripheral tolerance mechanisms are essential for their regulation. We report the role of proinsulin (PI) expression on the development and activation of insulin-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8422e6a2efec236558049c58081aaf66
https://pubmed.ncbi.nlm.nih.gov/27495224
https://pubmed.ncbi.nlm.nih.gov/27495224
Autor:
Lewis, Mark D., de Leenheer, Evy, Fishman, Sigal, Siew, Lai Khai, Gross, Gideon, Wong, F. Susan
Murine adoptive CD8+ T-cell immunotherapy studies require the generation of large numbers of high viability CD8+ cells. Here we report a tissue culture protocol for the reliable expansion of CD8+ T-cells derived from murine spleen to give a 20-fold e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::827116744eb4a79fa9a4f3aa937777d9
Publikováno v:
International Journal of Environmental Analytical Chemistry. 83:417-426
Although polyclonal antisera have been used for immunodiagnostic measurement of aldicarb, both as components of commercial kits and as stand-alone products, no monoclonal antibody (MAb) reactive to this carbamate pesticide has yet been described. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db35e00e89918e75da43dd5be6c807c1
https://doi.org/10.1080/0306731031000099819
https://doi.org/10.1080/0306731031000099819
Autor:
Mark D, Lewis, Evy, de Leenheer, Sigal, Fishman, Lai Khai, Siew, Gideon, Gross, F Susan, Wong
Publikováno v:
Journal of Immunological Methods
Murine adoptive CD8 + T-cell immunotherapy studies require the generation of large numbers of high viability CD8 + cells. Here we report a tissue culture protocol for the reliable expansion of CD8 + T-cells derived from murine spleen to give a 20-fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::411d521fbafc82cc228032c592cd3dd1
https://pubmed.ncbi.nlm.nih.gov/25602136
https://pubmed.ncbi.nlm.nih.gov/25602136
Autor:
Thayer, Terri C., Pearson, James A., De Leenheer, Evy, Hanna, Stephanie J., Boldison, Joanne, Davies, Joanne, Tsui, Adrian, Ahmed, Sartaj, Easton, Peter, Lai Khai Siew, Li Wen, Wong, F. Susan, Siew, Lai Khai, Wen, Li
Publikováno v:
Diabetes; Nov2016, Vol. 65 Issue 11, p3429-3439, 11p, 1 Chart, 7 Graphs
Akademický článek
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Autor:
Li Wen, Stephen Chapman, Christopher Viret, Florence Susan Wong, Lai Khai Siew, Gwen S. Scott, Ian J. Thomas
Publikováno v:
Diabetes
OBJECTIVE We have previously reported a highly diabetogenic CD8 T-cell clone, G9C8, in the nonobese diabetic (NOD) mouse, specific to low-avidity insulin peptide B15-23, and cells responsive to this antigen are among the earliest islet infiltrates. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6c454c987d57fb5d253a88e55c81fd
https://pubmed.ncbi.nlm.nih.gov/19208910
https://pubmed.ncbi.nlm.nih.gov/19208910
Publikováno v:
Integrated Uncertainty in Knowledge Modelling & Decision Making: 5th International Symposium, IUKM 2016, Da Nang, Vietnam, November 30- December 2, 2016, Proceedings; 2016, p397-408, 12p