Zobrazeno 1 - 10 of 1 718 pro vyhledávání: '"Lahdenranta, J."'
1
Akademický článek
Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide.
Autor: El Fakiri M; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Regupathy AR; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Uhlmann L; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Ayada N; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Geis NM; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Domogalla LC; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Lahdenranta J; Bicycle Therapeutics, 35 Cambridgepark Drive, Cambridge, MA, 02140, United States., Blakeman B; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Wood F; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Meyer PT; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany., Huxley P; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Eder M; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Mudd GE; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Eder AC; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Publikováno v: Theranostics [Theranostics] 2024 Aug 06; Vol. 14 (12), pp. 4701-4712. Date of Electronic Publication: 2024 Aug 06 (Print Publication: 2024).
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2
Akademický článek
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3
Akademický článek
BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors.
Autor: Rigby M; Bicycle TX Ltd., Cambridge, United Kingdom., Bennett G; Bicycle TX Ltd., Cambridge, United Kingdom., Chen L; Bicycle TX Ltd., Cambridge, United Kingdom., Mudd GE; Bicycle TX Ltd., Cambridge, United Kingdom., Harrison H; Amphista Therapeutics, The Cori Building, Cambridge, United Kingdom., Beswick PJ; Bicycle TX Ltd., Cambridge, United Kingdom., Van Rietschoten K; Bicycle TX Ltd., Cambridge, United Kingdom., Watcham SM; Kymab Ltd., The Bennet Building, Babraham Research Campus, Cambridge, United Kingdom., Scott HS; Bicycle TX Ltd., Cambridge, United Kingdom., Brown AN; Bicycle TX Ltd., Cambridge, United Kingdom., Park PU; Orum Therapeutics, Cambridge, Massachusetts., Campbell C; Bicycle Therapeutics, Inc., Lexington, Massachusetts., Haines E; Ikena Oncology, Boston, Massachusetts., Lahdenranta J; Bicycle Therapeutics, Inc., Lexington, Massachusetts., Skynner MJ; Bicycle TX Ltd., Cambridge, United Kingdom., Jeffrey P; Bicycle TX Ltd., Cambridge, United Kingdom., Keen N; Bicycle Therapeutics, Inc., Lexington, Massachusetts., Lee K; Bicycle TX Ltd., Cambridge, United Kingdom.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Dec 02; Vol. 21 (12), pp. 1747-1756.
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4
Akademický článek
Discovery and Optimization of a Synthetic Class of Nectin-4-Targeted CD137 Agonists for Immuno-oncology.
Autor: Upadhyaya P; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., Kristensson J; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge CB22 3AT, U.K., Lahdenranta J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., Repash E; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., Ma J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., Kublin J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., Mudd GE; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge CB22 3AT, U.K., Luus L; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., Jeffrey P; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge CB22 3AT, U.K., Hurov K; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., McDonnell K; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States., Keen N; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Jul 28; Vol. 65 (14), pp. 9858-9872. Date of Electronic Publication: 2022 Jul 12.
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5
Akademický článek
Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma.
Autor: Wang Y; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Tian X; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang W; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang Z; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lazcano R; Departments of Pathology & Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Hingorani P; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Roth ME; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gill JD; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Harrison DJ; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Xu Z; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Jusu S; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kannan S; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lazar AJ; Departments of Pathology & Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Earley EJ; RTI International, Research Triangle Park, North Carolina., Erickson SW; RTI International, Research Triangle Park, North Carolina., Gelb T; Bicycle Therapeutics, Lexington, Massachusetts., Huxley P; Bicycle Therapeutics, Babraham Research Campus, Cambridge, United Kingdom., Lahdenranta J; Bicycle Therapeutics, Lexington, Massachusetts., Mudd G; Bicycle Therapeutics, Babraham Research Campus, Cambridge, United Kingdom., Kurmasheva RT; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, Texas., Houghton PJ; Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, Texas., Smith MA; Cancer Therapy Evaluation Program, NCI, Bethesda, Maryland., Kolb EA; Division of Pediatric Hematology/Oncology, A.I. duPont Hospital for Children, Wilmington, Delaware., Gorlick R; Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Jun 01; Vol. 21 (6), pp. 903-913.
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6
Akademický článek
BT7480, a novel fully synthetic Bicycle tumor-targeted immune cell agonist™ ( Bicycle TICA™) induces tumor localized CD137 agonism.
Autor: Hurov K; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Lahdenranta J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Upadhyaya P; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Haines E; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Cohen H; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Repash E; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Kanakia D; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Ma J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Kristensson J; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge, UK., You F; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Campbell C; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Witty D; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge, UK., Kelly M; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge, UK., Blakemore S; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Jeffrey P; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge, UK., McDonnell K; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Brandish P; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA., Keen N; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts, USA nicholas.keen@bicycletx.com.
Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Nov; Vol. 9 (11).
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7
Akademický článek
Bioinformatic characterization of ENPEP, the gene encoding a potential cofactor for SARS-CoV-2 infection.
Autor: Arppo, Antti1 (AUTHOR), Barker, Harlan1,2,3 (AUTHOR) harlan.barker@tuni.fi, Parkkila, Seppo1,2 (AUTHOR)
Publikováno v: PLoS ONE. 12/11/2024, Vol. 19 Issue 12, p1-37. 37p.
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8
Akademický článek
EphA2 in Cancer: Molecular Complexity and Therapeutic Opportunities.
Autor: Toracchio, Lisa1 (AUTHOR) lisa.toracchio@ior.it, Carrabotta, Marianna1 (AUTHOR) marianna.carrabotta@ior.it, Mancarella, Caterina1 (AUTHOR) caterina.mancarella@ior.it, Morrione, Andrea2 (AUTHOR) andrea.morrione@temple.edu, Scotlandi, Katia1 (AUTHOR) katia.scotlandi@ior.it
Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12191. 19p.
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9
Akademický článek
VEGF—Virus Interactions: Pathogenic Mechanisms and Therapeutic Applications.
Autor: Sánchez-Martínez, Cristina1 (AUTHOR) cristina.sanchez@ufv.es, Grueso, Esther1 (AUTHOR) esther.grueso@ufv.es, Calvo-López, Tania2,3,4 (AUTHOR) tania.calvo@cib.csic.es, Martinez-Ortega, Jorge2,3 (AUTHOR) jorge.martinezortega@uam.es, Ruiz, Ana2,3 (AUTHOR) anaruizmedina26@gmail.com, Almendral, José M.2,3 (AUTHOR) jmalmendral@cbm.csic.es
Publikováno v: Cells (2073-4409). Nov2024, Vol. 13 Issue 21, p1815. 27p.
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10
Akademický článek
The axis of tumor-associated macrophages, extracellular matrix proteins, and cancer-associated fibroblasts in oncogenesis.
Autor: Yu, Shuhong1 (AUTHOR), Wang, Siyu1 (AUTHOR), Wang, Xuanyu2 (AUTHOR), Xu, Ximing1 (AUTHOR) doctorxu120@aliyun.com
Publikováno v: Cancer Cell International. 10/7/2024, Vol. 24 Issue 1, p1-30. 30p.
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