Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease : An Individual-Level Meta-Analysis

Autor: Schillemans, T., Tragante, V., Maitusong, B., Gigante, B., Cresci, S., Laguzzi, F., Vikstrom, M., Richards, M., Pilbrow, A., Cameron, V., Foco, L., Doughty, R.N., Kuukasjarvi, P., Allayee, H., Hartiala, J.A., Tang, W.H.W., Lyytikainen, L.P., Nikus, K., Laurikka, J.O., Srinivasan, S., Mordi, I.R., Trompet, S., Kraaijeveld, A., Setten, J. van, Gijsberts, C.M., Maitland-van der Zee, A.H., Saely, C.H., Gong, Y., Johnson, J.A., Cooper-DeHoff, R.M., Pepine, C.J., Casu, G., Leiherer, A., Drexel, H., Horne, B.D., Laan, S.W. van der, Marziliano, N., Hazen, S.L., Sinisalo, J., Kahonen, M., Lehtimaki, T., Lang, C.C., Burkhardt, R., Scholz, M., Jukema, J.W., Eriksson, N., Akerblom, A., James, S., Held, C., Hagstrom, E., Spertus, J.A., Algra, A., Faire, U. de, Akesson, A., Asselbergs, F.W., Patel, R.S., Leander, K.

Publikováno v: Frontiers in Physiology, 13
Frontiers in Physiology, 13. FRONTIERS MEDIA SA
Frontiers in physiology, 13:909870. Frontiers Media S.A.

Contains fulltext : 283506.pdf (Publisher’s version ) (Open Access) Background: The knowledge of factors influencing disease progression in patients with established coronary heart disease (CHD) is still relatively limited. One potential pathway is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3b41ac3f7ec707ef5e8eea7f48704a37
http://hdl.handle.net/10138/347156

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study

Autor: Bonomi, A., Veglia, F., Baldassarre, D., Strawbridge, R. J., Golabkesh, Z., Sennblad, B., Leander, K., Smit, A. J., Giral, P., Humphries, S. E., Tremoli, E., Hamsten, A., de Faire, U., Gigante, B., Sirtori, C. R., Castelnuovo, S., Calabresi, L., Amato, M., Frigerio, B., Ravani, A., Sansaro, D., Coggi, D., Tedesco, C. C., Eriksson, P., Silveira, A., Laguzzi, F., Cooper, J., Acharya, J., Huttunen, K., Rauramaa, E., Pekkarinen, H., Penttila, I. M., Torronen, J., Rauramaa, R., van Gessel, A. I., van Roon, A. M., Teune, G. C., Kuipers, W. D., Bruin, M., Nicolai, A., Haarsma-Jorritsma, P., Mulder, D. J., Bilo, H. J. G., Smeets, G. H., Beaudeux, J. L., Kahn, J. F., Carreau, V., Kontush, A., Karppi, J., Nurmi, T., Nyyssonen, K., Salonen, R., Tuomainen, T. P., Tuomainen, J., Kauhanen, J., Kurl, S., Vaudo, G., Alaeddin, A., Siepi, D., Lupattelli, G., Mannarino, E.

Publikováno v: GENES AND IMMUNITY, 100-108. Nature Publishing Group
ISSUE=2;STARTPAGE=100;ENDPAGE=108;ISSN=1466-4879;TITLE=GENES AND IMMUNITY
Genes and Immunity

The genes regulating circulating levels of soluble gp130 (sgp130), the antagonist of the inflammatory response in atherosclerosis driven by interleukin 6, are largely unknown. Aims of the present study were to identify genetic loci associated with ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::230d4937385f16804f03c692cc53b473
https://research.rug.nl/en/publications/18db96c0-3e1c-48aa-9b56-f9e3e0d2151f

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Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality

Autor: MARKLUND, M., WU, J. H. Y., IMAMURA, F., DEL GOBBO, L. C., FRETTS, A., DE GOEDE, J., Shi, P., TINTLE, N., WENNBERG, M., ASLIBEKYAN, S., CHEN, T. A., DE OLIVEIRA OTTO, M. C., Hirakawa, Y., ERIKSEN, H. H., KROGER, J., LAGUZZI, F., LANKINEN, M., Murphy, R. A., PREM, K., Samieri, C., Virtanen, J., WOOD, A. C., Wong, K., YANG, W. S., Zhou, X., BAYLIN, A., BOER, J. M. A., BROUWER, I. A., Campos, H., CHAVES, P. H. M., CHIEN, K. L., DE FAIRE, U., DJOUSSE, L., EIRIKSDOTTIR, G., EL-ABBADI, N., FOROUHI, N. G., MICHAEL GAZIANO, J., GELEIJNSE, J. M., GIGANTE, B., GILES, G., GUALLAR, E., GUDNASON, V., HARRIS, T., HARRIS, W. S., Helmer, Catherine, HELLENIUS, M. L., Hodge, A., Hu, F. B., JACQUES, P. F., JANSSON, J. H., Kalsbeek, A., Khaw, K. T., Koh, W. P., Laakso, M., LEANDER, K., LIN, H. J., LIND, L., LUBEN, R., Luo, J., MCKNIGHT, B., MURSU, J., Ninomiya, T., Overvad, K., PSATY, B. M., RIMM, E., SCHULZE, M. B., SISCOVICK, D., SKJELBO NIELSEN, M., SMITH, A. V., STEFFEN, B. T., STEFFEN, L., Sun, Q., SUNDSTROM, J., TSAI, M. Y., TUNSTALL-PEDOE, H., UUSITUPA, M. I. J., VAN DAM, R. M., VEENSTRA, J., MONIQUE VERSCHUREN, W. M., Wareham, N., WILLETT, W., Woodward, M., Yuan, J. M., Micha, R., LEMAITRE, R. N., Mozaffarian, D.

Publikováno v: Circulation
Circulation, American Heart Association, 2019, 139 (21), pp.2422-2436. ⟨10.1161/circulationaha.118.038908⟩

International audience; BACKGROUND: Global dietary recommendations for and cardiovascular effects of linoleic acid, the major dietary omega-6 fatty acid, and its major metabolite, arachidonic acid, remain controversial. To address this uncertainty an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5c3fffb2efa3b9fb461f6b3ba8cb8996
http://hdl.handle.net/20.500.12278/39255

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Autor: Feitosa, MF, Kraja, AT, Chasman, DI, Sung, YJ, Winkler, TW, Ntalla, I, Guo, X, Franceschini, N, Cheng, CY, Sim, X, Vojinovic, D, Marten, J, Musani, SK, Li, C, Bentley, AR, Brown, MR, Schwander, K, Richard, MA, Noordam, R, Aschard, H, Bartz, TM, Bielak, LF, Dorajoo, R, Fisher, V, Hartwig, FP, Horimoto, ARVR, Lohman, KK, Manning, AK, Rankinen, T, Smith, AV, Tajuddin, SM, Wojczynski, MK, Alver, M, Boissel, M, Cai, Q, Campbell, A, Chai, JF, Chen, X, Divers, J, Gao, C, Goel, A, Hagemeijer, Y, Harris, SE, He, M, Hsu, FC, Jackson, AU, Kähönen, M, Kasturiratne, A, Komulainen, P, Kühnel, B, Laguzzi, F, Luan, J, Matoba, N, Nolte, IM, Padmanabhan, S, Riaz, M, Rueedi, R, Robino, A, Said, MA, Scott, RA, Sofer, T, Stančáková, A, Takeuchi, F, Tayo, BO, Van Der Most, PJ, Varga, TV, Vitart, V, Wang, Y, Ware, EB, Warren, HR, Weiss, S, Wen, W, Yanek, LR, Zhang, W, Zhao, JH, Afaq, S, Amin, N, Amini, M, Arking, DE, Aung, T, Boerwinkle, E

Publikováno v: Feitosa, MF; Kraja, AT; Chasman, DI; Sung, YJ; Winkler, TW; Ntalla, I; et al.(2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS ONE, 13(6). doi: 10.1371/journal.pone.0198166. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9bn3n17g

© 2018 Public Library of Science. All Rights Reserved. Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::167bd2cd3b77dfae8c9e5b5785248ffb
http://www.escholarship.org/uc/item/9bn3n17g