Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions

Autor: Pou, J, Martinez-Gonzalez, J, Rebollo, A, Rodriguez, C, Rodriguez-Calvo, R, Martin-Fuentes, P, Cenarro, A, Civeira, F, Laguna, JC, Alegret, M

Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Type II interleukin-1 receptor (IL-1R2) is a non-signaling decoy receptor that negatively regulates the activity of interleukin-1 (IL-1), a pro-inflammatory cytokine involved in atherogenesis. In this article we assessed the relevance of IL-1R2 in at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::8b83b9f5efa70ac3bba2fd92fc843fba
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=11827

Cyclooxygenase 2 Inhibition Exacerbates Palmitate-Induced Inflammation and Insulin Resistance in Skeletal Muscle Cells

Autor: Coll, T, Palomer, X, Blanco-Vaca, F, Escola-Gil, JC, Sanchez, RM, Laguna, JC, Vazquez-Carrera, M

Publikováno v: ENDOCRINOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Palmitate-induced inflammation is involved in the development of insulin resistance in skeletal muscle cells. Here we evaluated the effect of the saturated fatty acid palmitate and the monounsaturated fatty acid oleate on Toll-like receptors (TLR)-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::dfd77ac62ef12029105a004f960958bb
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12854

TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model

Autor: Palomer FX, Alvarez-Guardia D, Rodríguez-Calvo R, Coll T, Laguna JC, Davidson MM, Chan TO, Feldman AM, Vazquez M

Publikováno v: CARDIOVASC RES
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname

Inflammatory responses in the heart that are driven by sustained increases in cytokines have been associated with several pathological processes, including cardiac hypertrophy and heart failure. Emerging data suggest a link between cardiomyopathy and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::248fcc130092679bb1561ffad11e45b4
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=11986

Hepatic gene expression changes in an experimental model of accelerated senescence: the SAM-P8 mouse

Autor: Vilà L, Roglans N, Alegret M, Camins A, Pallàs M, Sánchez RM, Vazquez M, Laguna JC

Publikováno v: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname

The senescence-accelerated mouse (SAM) is an experimental model of aging, established through phenotypic selection from a common genetic pool of AKR/J mice. Here we use complementary DNA microarray, Western blot, and electrophoretic mobility shift as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::28d6c1d133a6a3ac7e191c9fda0be3b1
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12021

Atorvastatin inhibits GSK-3beta phosphorylation by cardiac hypertrophic stimuli

Autor: Planavila A, Rodríguez-Calvo R, Palomer FX, Coll T, Sánchez RM, Merlos M, Laguna JC, Vazquez M

Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

In this study we examined the effect of the statin atorvastatin on the Akt/GSK-3beta pathway. Our findings indicate that atorvastatin treatment for 15 days inhibited pressure overload-induced cardiac hypertrophy and prevented nuclear translocation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::435ff569d8b3a81032ca38fd6eb9e282
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=11641