Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lagrue, Kathryn"'
Autor:
Pageon, Sophie V., Aquino, Gerardo, Lagrue, Kathryn, Köhler, Karsten, Endres, Robert G., Davis, Daniel M.
Publikováno v:
Biophysical Journal, Volume 105, 1-10, (2013)
Natural Killer (NK) cell activation is dynamically regulated by numerous activating and inhibitory surface receptors that accumulate at the immune synapse. Quantitative analysis of receptor dynamics has been limited by methodologies which rely on ind
Externí odkaz:
http://arxiv.org/abs/1310.2415
Autor:
Gil-Krzewska, Aleksandra, Saeed, Mezida B., Oszmiana, Anna, Fischer, Elizabeth R., Lagrue, Kathryn, Gahl, William A., Introne, Wendy J., Coligan, John E., Davis, Daniel M., Krzewski, Konrad
Publikováno v:
In The Journal of Allergy and Clinical Immunology September 2018 142(3):914-927
Publikováno v:
In Blood 2 July 2015 126(1):50-60
Autor:
Gil-Krzewska, Aleksandra, Saeed, Mezida B, Oszmiana, Anna, Fischer, E, Lagrue, Kathryn, Gahl, William A, Introne, Wendy J, Coligan, John E, Davis, Daniel M, Krzewski, Konrad
Publikováno v:
Gil-Krzewska, A, Saeed, M B, Oszmiana, A, Fischer, E, Lagrue, K, Gahl, W A, Introne, W J, Coligan, J E, Davis, D M & Krzewski, K 2017, ' An actin cytoskeletal barrier inhibits lytic granule release from Natural Killer cells in Chediak-Higashi syndrome ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2017.10.040
BackgroundChediak-Higashi syndrome (CHS) is a rare disorder caused by biallelic mutations in the LYST gene, resulting in formation of giant lysosomes or lysosome-related organelles in several cell types. The disease is characterized by immunodeficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::1fd835afc69026baa2badf87343e49ce
https://www.research.manchester.ac.uk/portal/en/publications/an-actin-cytoskeletal-barrier-inhibits-lytic-granule-release-from-natural-killer-cells-in-chediakhigashi-syndrome(935d87b1-058c-4c0e-92ee-9edeb703652f).html
https://www.research.manchester.ac.uk/portal/en/publications/an-actin-cytoskeletal-barrier-inhibits-lytic-granule-release-from-natural-killer-cells-in-chediakhigashi-syndrome(935d87b1-058c-4c0e-92ee-9edeb703652f).html
Autor:
Lagrue, Kathryn1,2, Carisey, Alex1, Oszmiana, Anna1, Kennedy, Philippa R.1, Williamson, David J.1, Cartwright, Adam1,2, Barthen, Charlotte1,2, Davis, Daniel M.1,2
Publikováno v:
Immunological Reviews. Nov2013, Vol. 256 Issue 1, p203-221. 19p.
Autor:
Lagrue, Kathryn
As multiple myeloma (MM) progresses, Natural Killer (NK) cell responses decline against malignant plasma cells. The immunomodulatory drug lenalidomide is widely used for the treatment of MM but its influence on NK cell biology is unclear. Here, a com
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676822
Autor:
Pageon, Sophie V., Aquino, Gerardo, Lagrue, Kathryn, Köhler, Karsten, Endres, Robert G., Davis, Daniel M.
Publikováno v:
Biophysical Journal; November 2013, Vol. 105 Issue: 9 p1987-1996, 10p
Akademický článek
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Autor:
David Williamson, Adam N.R. Cartwright, Alex Carisey, Charlotte Barthen, Daniel M. Davis, Philippa R. Kennedy, Anna Oszmiana, Kathryn Lagrue
Publikováno v:
Immunological reviews. 256(1)
Natural killer (NK) cells discriminate between healthy and unhealthy target cells through a balance of activating and inhibitory signals at direct intercellular contacts called immune synapses. Rearrangements in the cellular cytoskeleton have long be