A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia.

Autor: Rodden LN; Departments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Rummey C; Clinical Data Science GmbH, Basel, Switzerland., Dong YN; Departments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Lagedrost S; Departments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Regner S; Departments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Brocht A; University of Rochester, Rochester, NY, United States., Bushara K; University of Minnesota, Minneapolis, MN, United States., Delatycki MB; Murdoch Children's Research Institute, Victorian Clinical Genetics Services, Melbourne, VIC, Australia., Gomez CM; Department of Neurology, The University of Chicago, Chicago, IL, United States., Mathews K; Departments of Pediatrics and Neurology, University of Iowa Carver College of Medicine, Iowa City, IA, United States., Murray S; Department of Pathology, School of Medicine, University of California, San Diego, San Diego, CA, United States., Perlman S; Department of Neurology, University of California, Los Angeles, Los Angeles, CA, United States., Ravina B; Praxis Precision Medicines, Boston, MA, United States., Subramony SH; Department of Neurology, University of Florida, College of Medicine, Gainesville, FL, United States., Wilmot G; Department of Neurology, Emory University School of Medicine, Atlanta, GA, United States., Zesiewicz T; Department of Neurology, University of South Florida, Tampa, FL, United States., Bolotta A; The Scripps Research Institute, La Jolla, CA, United States., Domissy A; The Scripps Research Institute, La Jolla, CA, United States., Jespersen C; The Scripps Research Institute, La Jolla, CA, United States., Ji B; The Scripps Research Institute, La Jolla, CA, United States., Soragni E; The Scripps Research Institute, La Jolla, CA, United States., Gottesfeld JM; The Scripps Research Institute, La Jolla, CA, United States., Lynch DR; Departments of Pediatrics and Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Publikováno v: Frontiers in molecular biosciences [Front Mol Biosci] 2022 Sep 05; Vol. 9, pp. 933788. Date of Electronic Publication: 2022 Sep 05 (Print Publication: 2022).

Altered dNTP pools accelerate tumor formation in mice.

Autor: Tran, Phong, Mishra, Pradeep, Williams, Leonard G, Moskalenko, Roman, Sharma, Sushma, Nilsson, Anna Karin, Watt, Danielle L, Andersson, Pernilla, Bergh, Anders, Pursell, Zachary F, Chabes, Andrei

Publikováno v: Nucleic Acids Research; 11/11/2024, Vol. 52 Issue 20, p12475-12486, 12p

Identification and validation of an E2F-related gene signature for predicting recurrence-free survival in human prostate cancer.

Autor: Yang, Cheng^1,2,3 (AUTHOR), Chen, Lei^1,2,3 (AUTHOR), Niu, Qingsong^1,2,3 (AUTHOR), Ge, Qintao^1,2,3 (AUTHOR), Zhang, Jiong^1,2,3 (AUTHOR), Tao, Junyue^1,2,3 (AUTHOR), Zhou, Jun^1,2,3 (AUTHOR) urodoctorzhou@163.com, Liang, Chaozhao^1,2,3 (AUTHOR) liang_chaozhao@ahmu.edu.cn

Publikováno v: Cancer Cell International. 12/5/2022, Vol. 22 Issue 1, p1-14. 14p.

Improved cognitive impairments by silencing DMP1 via enhancing the proliferation of neural progenitor cell in Alzheimer‐like mice.

Autor: Zhao, Huimin¹ (AUTHOR), Wei, Jie¹ (AUTHOR), Du, Yanan¹ (AUTHOR), Chen, Peipei¹ (AUTHOR), Liu, Xiaoquan¹ (AUTHOR) haochenliu@cpu.edu.cn, Liu, Haochen¹ (AUTHOR) haochenliu@cpu.edu.cn

Publikováno v: Aging Cell. May2022, Vol. 21 Issue 5, p1-16. 16p.

Emerging antioxidant therapies in Friedreich's ataxia.

Autor: Edzeamey, Fred Jonathan, Ramchunder, Zenouska, Pourzand, Charareh, Virmouni, Sara Anjomani

Publikováno v: Frontiers in Pharmacology; 2024, p1-17, 17p