Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Lagache, Thibault"'
Autor:
Salavessa, Laura, Lagache, Thibault, Malardé, Valérie, Grassart, Alexandre, Olivo-Marin, Jean-Christophe, Canette, Alexis, Trichet, Michael, Sansonetti, Philippe J., Sauvonnet, Nathalie
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Sep . 118(37), 1-12.
Externí odkaz:
https://www.jstor.org/stable/27075746
Akademický článek
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Autor:
Lagache, Thibault, Holcman, David
A certain class of viruses replicates inside a cell if they can enter the nucleus through one of many small target pores, before being permanently trapped or degraded. We adopt for viral motion a switching stochastic process model and we estimate her
Externí odkaz:
http://arxiv.org/abs/1607.02479
Influenza viruses enter a cell via endocytosis after binding to the surface. During the endosomal journey, acidification triggers a conformational change of the virus spike protein hemagglutinin (HA) that results in escape of the viral genome from th
Externí odkaz:
http://arxiv.org/abs/1510.06382
Gene delivery of nucleic acid to the cell nucleus is a fundamental step in gene therapy. In this review of modeling drug and gene delivery, we focus on the particular stage of plasmid DNA or virus cytoplasmic trafficking. A challenging problem is to
Externí odkaz:
http://arxiv.org/abs/1109.1495
Autor:
Lagache, Thibault, Holcman, David
Virus trafficking is fundamental for infection success and plasmid cytosolic trafficking is a key step of gene delivery. Based on the main physical properties of the cellular transport machinery such as microtubules, motor proteins, our goal here is
Externí odkaz:
http://arxiv.org/abs/0712.3383
Autor:
Lagache, Thibault1,2 (AUTHOR) thibault.lagache@pasteur.fr, Hanson, Alison1,2,3 (AUTHOR), Pérez-Ortega, Jesús E.1 (AUTHOR), Fairhall, Adrienne4,5 (AUTHOR), Yuste, Rafael1,2 (AUTHOR)
Publikováno v:
PLoS Computational Biology. 10/8/2021, p1-25. 25p. 1 Diagram, 4 Charts, 5 Graphs.
Autor:
Boissan, Mathieu, Montagnac, Guillaume, Shen, Qinfang, Griparic, Lorena, Guitton, Jérôme, Romao, Maryse, Sauvonnet, Nathalie, Lagache, Thibault, Lascu, Ioan, Raposo, Graça, Desbourdes, Céline, Schlattner, Uwe, Lacombe, Marie-Lise, Polo, Simona, van der Bliek, Alexander M., Roux, Aurélien, Chavrier, Philippe
Publikováno v:
Science, 2014 Jun . 344(6191), 1510-1515.
Externí odkaz:
http://www.jstor.org/stable/24744778
Akademický článek
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Autor:
Mukherjee, Suvadip, Meas-Yedid, Vannary, Bokobza, Marc, Lagache, Thibault, Corthay, Alexandre, Olivo-Marin, Jean-Christophe
Publikováno v:
2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI)
2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI), Mar 2022, Kolkata, India. pp.1-5, ⟨10.1109/ISBI52829.2022.9761498⟩
2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI), Mar 2022, Kolkata, India. pp.1-5, ⟨10.1109/ISBI52829.2022.9761498⟩
International audience; A pattern analysis approach is proposed to model spatial interaction between the immune cells and the tumor islets within the tumor microenvironment. Embedded in a statistical null hypothesis paradigm, the proposed solution pr