Expression of human RECQL5 in Saccharomyces cerevisiae causes transcription defects and transcription-associated genome instability.

Autor: Lafuente-Barquero J; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, 41092, Seville, Spain.; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012, Seville, Spain., Svejstrup JQ; University of Copenhagen, Copenhagen, Denmark.; Francis Crick Institute, London, UK., Luna R; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, 41092, Seville, Spain. rlvaro@us.es.; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012, Seville, Spain. rlvaro@us.es., Aguilera A; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, 41092, Seville, Spain.; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012, Seville, Spain.

Publikováno v: Molecular genetics and genomics : MGG [Mol Genet Genomics] 2024 May 26; Vol. 299 (1), pp. 59. Date of Electronic Publication: 2024 May 26.

MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells.

Autor: Duwe L; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Munoz-Garrido P; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Lewinska M; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Lafuente-Barquero J; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Satriano L; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Høgdall D; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark; Department of Oncology, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Taranta A; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Nielsen BS; Bioneer, Kogle Alle 2, DK-2970, Hørsholm, Denmark., Ghazal A; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Matter MS; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Banales JM; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute, Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, 'Instituto de Salud Carlos III'), Spain; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain; Department of Biochemistry and Genetics, School of Sciences, University of Navarra, Pamplona, Spain., Aldana BI; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China., Marquardt JU; Department of Medicine I, University Medical Center Schleswig-Holstein-Campus Lübeck, 23558 Lübeck, Germany., Roberts LR; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA., Oliveira RC; Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of Environment, Genetics and Oncobiology (CIMAGO), Institute of Biophysics, Faculty of Medicine, University of Coimbra, Portugal; Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Koshiol J; Division of Cancer Epidemiology and Genetics, NIH, USA., O'Rourke CJ; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark., Andersen JB; Biotech Research & Innovation Centre (BRIC), Department of Health and Medical Sciences, University of Copenhagen, Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark. Electronic address: jesper.andersen@bric.ku.dk.

Publikováno v: Journal of hepatology [J Hepatol] 2023 Feb; Vol. 78 (2), pp. 364-375. Date of Electronic Publication: 2022 Oct 28.

Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes.

Autor: Nepal C; Biotech Research and Innovation Centre, Department of Health and Medical Sciences, University of Copenhagen, Denmark., Zhu B; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., O'Rourke CJ; Biotech Research and Innovation Centre, Department of Health and Medical Sciences, University of Copenhagen, Denmark., Bhatt DK; Biotech Research and Innovation Centre, Department of Health and Medical Sciences, University of Copenhagen, Denmark., Lee D; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Song L; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Wang D; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Van Dyke AL; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Choo-Wosoba H; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Liu Z; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Hildesheim A; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Goldstein AM; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Dean M; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., LaFuente-Barquero J; Biotech Research and Innovation Centre, Department of Health and Medical Sciences, University of Copenhagen, Denmark., Lawrence S; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Mutreja K; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Olanich ME; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Lorenzo Bermejo J; Statistical Genetics Research Group, Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany., Ferreccio C; Department of Public Health, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), FONDAP, Santiago, Chile., Roa JC; Department of Pathology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Rashid A; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hsing AW; Stanford Cancer Institute and Stanford Prevention Research Center, Department of Medicine, Stanford School of Medicine, Stanford, CA, USA., Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China., Chanock SJ; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA., Araya JC; Advanced Center for Chronic Diseases (ACCDiS), FONDAP, Santiago, Chile; Hospital Dr. Hernán Henríquez Aravena, Temuco, Chile; Department of Pathology, Faculty of Medicine, Universidad de La Frontera, Temuco, Chile., Andersen JB; Biotech Research and Innovation Centre, Department of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address: jesper.andersen@bric.ku.dk., Koshiol J; Division of Cancer Epidemiology and Genetics, NIH, Rockville, MD, USA. Electronic address: koshiolj@mail.nih.gov.

Publikováno v: Journal of hepatology [J Hepatol] 2021 May; Vol. 74 (5), pp. 1132-1144. Date of Electronic Publication: 2020 Dec 01.

Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner.

Autor: Lafuente-Barquero J; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain., García-Rubio ML; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain., Martin-Alonso MS; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain., Gómez-González B; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain., Aguilera A; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain.

Publikováno v: ELife [Elife] 2020 Aug 04; Vol. 9. Date of Electronic Publication: 2020 Aug 04.

Unveil Intrahepatic Cholangiocarcinoma Heterogeneity through the Lens of Omics and Multi-Omics Approaches.

Autor: Porreca, Veronica¹ (AUTHOR) corbella.2016275@studenti.uniroma1.it, Barbagallo, Cristina² (AUTHOR) cbarbagallo@unict.it, Corbella, Eleonora¹ (AUTHOR) peres.1461165@studenti.uniroma1.it, Peres, Marco¹ (AUTHOR), Stella, Michele² (AUTHOR) michelestella7@gmail.com, Mignogna, Giuseppina³ (AUTHOR) pina.mignogna@uniroma1.it, Maras, Bruno³ (AUTHOR) bruno.maras@uniroma1.it, Ragusa, Marco² (AUTHOR) mragusa@unict.it, Mancone, Carmine¹ (AUTHOR) veronica.porreca@uniroma1.it

Publikováno v: Cancers. Aug2024, Vol. 16 Issue 16, p2889. 40p.