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Dexamethasone Creates a Suppressive Microenvironment and Promotes Aspergillus fumigatus Invasion in a Human 3D Epithelial/Immune Respiratory Model

Autor: Luvanda, Maureen K., Posch, Wilfried, Noureen, Asma, Lafon, Eliott, Zaderer, Viktoria, Lass-Flörl, Cornelia, Wilflingseder, Doris

Publikováno v: Journal of Fungi, Vol 7, Iss 221, p 221 (2021)
Journal of Fungi
Volume 7
Issue 3

Lung immunity and susceptibility to infections is subject to interactions between the epithelial layer and immune cells residing in the pulmonary space. Aspergillus (A.) fumigatus, the most prevalent pathogenic fungus, affects both upper and lower re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c9e855ad1aa59def738084a49ef4a6f7
https://www.mdpi.com/2309-608X/7/3/221

More Efficient Complement Activation by Anti-Aquaporin-4 Compared With Anti-Myelin Oligodendrocyte Glycoprotein Antibodies.

Autor: Lerch M; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Schanda K; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Lafon E; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Würzner R; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Mariotto S; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Dinoto A; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Wendel EM; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Lechner C; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Hegen H; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Rostásy K; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Berger T; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Wilflingseder D; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Höftberger R; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria., Reindl M; From the Clinical Department of Neurology (M.L., K.S., H.H., M.R.), Medical University of Innsbruck, Austria; Institute of Hygiene and Medical Microbiology (E.L., R.W., D.W.), Medical University of Innsbruck, Austria; Neurology Unit (S.M., A.D.), Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Italy; Department of Pediatric Neurology (E.M.W.), Olgahospital/Klinikum Stuttgart, Germany; Department of Pediatrics I (C.L.), Medical University of Innsbruck, Austria; Paediatric Neurology (K.R.), Witten/Herdecke University, Children's Hospital Datteln, Germany; Department of Neurology (T.B.), Medical University of Vienna, Austria; and Division of Neuropathology and Neurochemistry (C.L., R.H.), Department of Neurology, Medical University of Vienna, Austria. markus.reindl@i-med.ac.at.

Publikováno v: Neurology(R) neuroimmunology & neuroinflammation [Neurol Neuroimmunol Neuroinflamm] 2022 Nov 22; Vol. 10 (1). Date of Electronic Publication: 2022 Nov 22 (Print Publication: 2023).