Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laetitia Hellaudais"'
Autor:
Laurent Mazzolini, Christophe Cazaux, M.J. Pillaire, A Paganin, Justin Teissié, Laetitia Hellaudais, Muriel Golzio, Jean-Sébastien Hoffmann, Anne Bieth, M Izard, A Ledoux, Bettina Couderc
Publikováno v:
Gene Therapy. 14:752-759
RNA interference (RNAi)-mediated gene silencing approaches appear very promising for therapies based on the targeted inhibition of disease-relevant genes. The major hurdle to the therapeutic development of RNAi strategies remains, however, the effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5344c1b9e76cc924043ffc310333c852
https://doi.org/10.1038/sj.gt.3302920
https://doi.org/10.1038/sj.gt.3302920
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1770:137-142
Direct application of high voltage electric pulses of milliseconds duration to the skin of a mouse enhances in vivo intradermal delivery of injected therapeutic molecules such as DNA. The efficacy of gene transfer and expression is dependent on elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de4d2a1022264dcfc9c1965805cd86f
https://doi.org/10.1016/j.bbagen.2006.09.014
https://doi.org/10.1016/j.bbagen.2006.09.014
Autor:
Laetitia Hellaudais, Muriel Golzio, Jean-Michel Escoffre, Daniel Drocourt, Gérard Tiraby, Arnaud Debin, Jean-Paul Reynes, Justin Teissié
Publikováno v:
Technology in Cancer Research and Treatment
Technology in Cancer Research and Treatment, 2008, 7 (2), pp.109-116. ⟨10.1177/153303460800700203⟩
Technology in Cancer Research and Treatment, Adenine Press, 2008, 7 (2), pp.109-116. ⟨10.1177/153303460800700203⟩
Technology in Cancer Research and Treatment, 2008, 7 (2), pp.109-116. ⟨10.1177/153303460800700203⟩
Technology in Cancer Research and Treatment, Adenine Press, 2008, 7 (2), pp.109-116. ⟨10.1177/153303460800700203⟩
RNA interference appears as a promising tool for therapeutic gene silencing. A key limit is the delivery of the siRNA. A safe approach is to use a physical method such as in vivo electropulsation with contact electrodes. Getting a long lived silencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e32c154a1fffc4834d116c2e3c3626e
https://www.hal.inserm.fr/inserm-02439064
https://www.hal.inserm.fr/inserm-02439064
