Výsledky vyhledávání - "Laetitia Florenceau"

Akademický článek

Overexpression of meloe gene in melanomas is controlled both by specific transcription factors and hypomethylation.

Autor: Mathilde Bobinet, Virginie Vignard, Laetitia Florenceau, Francois Lang, Nathalie Labarriere, Agnès Moreau-Aubry

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e75421 (2013)

The melanoma antigens MELOE-1 and MELOE-2 are encoded by a messenger, called meloe, overexpressed in melanomas compared with other tumour cell types and healthy tissues. They are both able to elicit melanoma-specific T cell responses in melanoma pati

Externí odkaz: https://doaj.org/article/c77bf5b22fde4f0db0263c27d22b9484

Zobrazit plný text záznamu

Akademický článek

The melanoma antigens MELOE-1 and MELOE-2 are translated from a bona fide polycistronic mRNA containing functional IRES sequences.

Autor: Delphine Carbonnelle, Virginie Vignard, Delphine Sehedic, Agnes Moreau-Aubry, Laetitia Florenceau, Maud Charpentier, Wolfgang Mikulits, Nathalie Labarriere, François Lang

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e75233 (2013)

Our previous studies on melanoma antigens identified two new polypeptides, named MELOE-1 and MELOE-2, that are involved in immunosurveillance. Intriguingly, these antigens are coded by distinct open reading frames (ORF) of the meloe mRNA which is sig

Externí odkaz: https://doaj.org/article/1d1db63783204ef6b03048f3b617beab

Zobrazit plný text záznamu

Viral and tumor antigen-specific CD8 T-cell responses in Merkel cell carcinoma

Autor: Nathalie Labarrière, Pauline Gaboriaud, Laetitia Florenceau, Virginie Vignard, Delphine Fradin, Astrid Blom, Mahtab Samimi, Thibault Kervarrec, Houssem Benlalam, Pascal Aumond, Nadine Gervois, Antoine Touzé

Publikováno v: Cellular Immunology
Cellular Immunology, Elsevier, 2019, 344, pp.103961. ⟨10.1016/j.cellimm.2019.103961⟩
Cellular Immunology, 2019, 344, 8 p. ⟨10.1016/j.cellimm.2019.103961⟩
Cellular Immunology, Elsevier, 2019, 344, 8 p. ⟨10.1016/j.cellimm.2019.103961⟩

International audience; Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous cancer, which is immunogenic, regardless of the presence of MCPyV (80% of cases). The identification of MCC-specific epitopes recognized by CD8 T cells is crucial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ed1bfb8227c1926138b3166bda344e
https://www.hal.inserm.fr/inserm-02284748/file/1-s2.0-S0008874919302266-main.pdf

Zobrazit plný text záznamu

Cancer vaccines: designing artificial synthetic long peptides to improve presentation of class I and class II T cell epitopes by dendritic cells

Autor: Léa Paolini, Olivier Adotevi, Maud Charpentier, E Dupel, Agnès Fortun, Emilie Dupré, Catherine Rabu, Nathalie Labarrière, Céline Beauvillain, L. Rangan, Jean-Baptiste Latouche, François Lang, Laetitia Florenceau

Publikováno v: OncoImmunology
OncoImmunology, Taylor & Francis, 2019, 8 (4), pp.e1560919. ⟨10.1080/2162402X.2018.1560919⟩
OncoImmunology, Taylor & Francis, 2019, pp.e1560919-2. ⟨10.1080/2162402x.2018.1560919⟩
Oncoimmunology
OncoImmunology, Vol 8, Iss 4 (2019)
OncoImmunology, 2019, pp.e1560919-2. ⟨10.1080/2162402x.2018.1560919⟩

International audience; There is now a consensus that efficient peptide vaccination against cancer requires that peptides should (i) be exclusively presented by professional APC and (ii) stimulate both CD4 and CD8-specific T cell responses. To this a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd5c6d1e4eb958168d0931139ddca4f
https://hal.archives-ouvertes.fr/hal-02131764/document

Zobrazit plný text záznamu

IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens

Autor: Delphine Carbonnelle, Michel Krempf, Nathalie Labarrière, François Lang, Maud Charpentier, Laetitia Florenceau, Agnès Fortun, Mikaël Croyal, Catherine Rabu

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2016, 7, ⟨10.18632/oncotarget.10923⟩
Oncotarget, Impact journals, 2016, 7 (37), pp.59704-59713. ⟨10.18632/oncotarget.10923⟩
Oncotarget, 2016, 7 (37), pp.59704-59713. ⟨10.18632/oncotarget.10923⟩
Oncotarget 37 (7), 59704-59713. (2016)

// Maud Charpentier 1 , Mikael Croyal 2, 3 , Delphine Carbonnelle 1 , Agnes Fortun 1 , Laetitia Florenceau 1, 4 , Catherine Rabu 1 , Michel Krempf 2, 3, 4 , Nathalie Labarriere 1, 4 , Francois Lang 1 1 CRCNA, INSERM, CNRS, Universite d’Angers, Univ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ab9674eccd8ff434f2cde6fbace64f
https://www.hal.inserm.fr/inserm-01409602

Zobrazit plný text záznamu

A lineage-specific methylation pattern controls the transcription of the polycistronic mRNA coding MELOE melanoma antigens

Autor: Laetitia Florenceau, Nathalie Labarrière, Benjamin Chalopin, Delphine Fradin, Agnès Moreau-Aubry

Publikováno v: Melanoma Research
Melanoma Research, 2015, ⟨10.1097/CMR.0000000000000167⟩
Melanoma Research, Lippincott, Williams & Wilkins, 2015, ⟨10.1097/CMR.0000000000000167⟩

International audience; We recently characterized two melanoma antigens MELOE-1 and MELOE-2 derived from a polycistronic RNA overexpressed in the melanocytic lineage. This transcription profile was because of hypomethylation of the meloe proximal pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f79a6b312d8de5f614e8d4efd3d2d3
https://www.hal.inserm.fr/inserm-01280880/document

Zobrazit plný text záznamu

PD-1 expression conditions T cell avidity within an antigen-specific repertoire

Autor: Sylvain Simon, François Lang, Laetitia Florenceau, Brigitte Dréno, Nathalie Labarrière, Virginie Vignard, Amir Khammari

Publikováno v: OncoImmunology
OncoImmunology, Taylor & Francis, 2015, ⟨10.1080/2162402X.2015.1104448⟩
OncoImmunology, 2015, ⟨10.1080/2162402X.2015.1104448⟩
Oncoimmunology

Despite its negative regulatory role on tumor-specific T cells, Programmed cell death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In cancer, PD-1 blockade partially reverses T cell dysfunction allowing the amplification of tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1bad092142b919334d7ab1199bd636
https://www.hal.inserm.fr/inserm-01280886/document

Zobrazit plný text záznamu

Soluble HLA-I/Peptide Monomers Mediate Antigen-Specific CD8 T Cell Activation through Passive Peptide Exchange with Cell-Bound HLA-I Molecules

Autor: Mathilde Allard, Laetitia Florenceau, Karine Bernardeau, Klara Echasserieau, Nadine Gervois, Romain Oger, François Lang, Nathalie Labarrière, Houssem Benlalam

Publikováno v: Journal of Immunology
Journal of Immunology, 2014, 192 (11), pp.5090-5097. ⟨10.4049/jimmunol.1303226⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2014, 192 (11), pp.5090-5097. ⟨10.4049/jimmunol.1303226⟩

Accumulating evidence that serum levels of soluble class I HLA molecules (sHLA-I) can, under various pathological conditions, correlate with disease stage and/or patient survival, has stimulated interest in defining whether sHLA-I can exert immunolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babe8ffa2f03b6899be4a4454720c013
https://www.hal.inserm.fr/inserm-02481105/document

Zobrazit plný text záznamu

The Melanoma Antigens MELOE-1 and MELOE-2 Are Translated from a Bona Fide Polycistronic mRNA Containing Functional IRES Sequences

Autor: Wolfgang Mikulits, Laetitia Florenceau, Agnès Moreau-Aubry, Nathalie Labarrière, Delphine Carbonnelle, Maud Charpentier, François Lang, Delphine Sehedic, Virginie Vignard

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (9), pp.e75233. ⟨10.1371/journal.pone.0075233⟩
PLoS ONE, Vol 8, Iss 9, p e75233 (2013)
PLoS ONE, 2013, 8 (9), pp.e75233. ⟨10.1371/journal.pone.0075233⟩

International audience; Our previous studies on melanoma antigens identified two new polypeptides, named MELOE-1 and MELOE-2, that are involved in immunosurveillance. Intriguingly, these antigens are coded by distinct open reading frames (ORF) of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0cf9d504021358654030934bd9e6bc
https://www.hal.inserm.fr/inserm-01726993

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání