Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laetitia Fioraso-Cartier"'
Autor:
Cedric Merlot, Sumio Watanabe, Tomonori Aoyama, Sophie Molango, David A. Brenner, Yong-Han Paik, Francesca Gaggini, Cedric Szyndralewiez, Laetitia Fioraso-Cartier, Freddy Heitz, Benoît Laleu, Patrick Page
Publikováno v:
Hepatology. 56:2316-2327
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) generates reactive oxygen species (ROS) in hepatic stellate cells (HSCs) during liver fibrosis. In response to fibrogenic agonists, such as angiotensin II (Ang II), the NOX1 components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c219bb45ff3e7839d8d50426dab9a2
https://doi.org/10.1002/hep.25938
https://doi.org/10.1002/hep.25938
Autor:
Angelo Gradia, Benoît Laleu, Laurène Cagnon, Mike Orchard, Sophie Houngninou-Molango, Guillaume Duboux, Freddy Heitz, Francesca Gaggini, Cedric Merlot, Patrick Page, Cedric Szyndralewiez, Laetitia Fioraso-Cartier
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:6989-6999
Pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives are new chemical entities with good and attractive druglikeness properties. A series of pyrazolo-pyrido-diazepine dione analogs demonstrated to be particularly amenable to lead optim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aee95a8c2207124860562df787e0e1a
https://doi.org/10.1016/j.bmc.2011.10.016
https://doi.org/10.1016/j.bmc.2011.10.016
Autor:
Guillaume Duboux, Sophie Houngninou-Molango, Cedric Merlot, Francesca Gaggini, Angelo Gradia, Patrick Page, Laetitia Fioraso-Cartier, Freddy Heitz, Benoît Laleu, Laurène Cagnon, Mike Orchard, Cedric Szyndralewiez
Publikováno v:
Journal of Medicinal Chemistry. 53:7715-7730
We describe the design, synthesis, and optimization of first-in-class series of inhibitors of NADPH oxidase isoform 4 (Nox4), an enzyme implicated in several pathologies, in particular idiopathic pulmonary fibrosis, a life-threatening and orphan dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477b650619687dec97bd074530449382
https://doi.org/10.1021/jm100773e
https://doi.org/10.1021/jm100773e
Autor:
Zahia Mahiout, Laetitia Fioraso-Cartier, Tamara Seredenina, Gianpaolo Chiriano, Karl-Heinz Krause, Zeynab Nayernia, Leonardo Scapozza, Olivier Plastre, Vincent Jaquet, Aleksandra Filippova
Publikováno v:
Free Radical Biology and Medicine, Vol. 86 (2015) pp. 239-249
NADPH oxidases (NOXs) constitute a family of enzymes generating reactive oxygen species (ROS) and are increasingly recognized as interesting drug targets. Here we investigated the effects of 10 phenothiazine compounds on NOX activity using an extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a3eee886a7944a64e3c9a58a7198ec
https://pubmed.ncbi.nlm.nih.gov/26013584
https://pubmed.ncbi.nlm.nih.gov/26013584
Autor:
Yvonne Westermaier, Leonardo Scapozza, William M. Nauseef, Julien Marcoux, Karl-Heinz Krause, Sally McCormick, Karen Bedard, Remo Perozzo, Becky A. Diebold, Kevin G. Leidal, Vincent Jaquet, Laetitia Fioraso-Cartier, Olivier Plastre, Eric Forest, Franck Fieschi
Publikováno v:
British Journal of Pharmacology, Vol. 164, No 2b (2011) pp. 507-20
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2011, 164 (2b), pp.507-520. ⟨10.1111/j.1476-5381.2011.01439.x⟩
British Journal of Pharmacology, 2011, 164 (2b), pp.507-520. ⟨10.1111/j.1476-5381.2011.01439.x⟩
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2011, 164 (2b), pp.507-520. ⟨10.1111/j.1476-5381.2011.01439.x⟩
British Journal of Pharmacology, 2011, 164 (2b), pp.507-520. ⟨10.1111/j.1476-5381.2011.01439.x⟩
International audience; BACKGROUND Celastrol is one of several bioactive compounds extracted from the medicinal plant Tripterygium wilfordii. Celastrol is used to treat inflammatory conditions, and shows benefits in models of neurodegenerative diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e10874075658d656a4bfec648fe107
https://pubmed.ncbi.nlm.nih.gov/21501142
https://pubmed.ncbi.nlm.nih.gov/21501142
Autor:
Tamara Seredenina, Roland Stocker, Laetitia Fioraso-Cartier, Olivier Basset, Stefania Schiavone, Karl-Heinz Krause, Zahia Mahiout, Vincent Jaquet, Olivier Plastre, Ghassan J. Maghzal, Zeynab-Mitra Nayernia
Publikováno v:
Free Radical Biology and Medicine. 65:S14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5354aa59cbc324bb2ec01711827e8b
https://doi.org/10.1016/j.freeradbiomed.2013.08.137
https://doi.org/10.1016/j.freeradbiomed.2013.08.137