Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laetitia, Prival"'
Autor:
Mélissa Delanne-Cuménal, Sylvain Lamoine, Mathieu Meleine, Youssef Aissouni, Laetitia Prival, Mathilde Fereyrolles, Julie Barbier, Christine Cercy, Ludivine Boudieu, Julien Schopp, Michel Lazdunski, Alain Eschalier, Stéphane Lolignier, Jérôme Busserolles
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116887- (2024)
Background: The metastasis of tumors into bone tissue typically leads to intractable pain that is both very disabling and particularly difficult to manage. We investigated here whether riluzole could have beneficial effects for the treatment of prost
Externí odkaz:
https://doaj.org/article/fba694993c0445fda652c636373e8655
Autor:
David Balayssac, Jérôme Busserolles, Catherine Broto, Cristelle Dalbos, Laetitia Prival, Sylvain Lamoine, Damien Richard, Mercedes Quintana, Aurélia Herbet, Sandrine Hilairet, Yang Hu, Irena Loryan, Warren E. Glaab, Laura Micheli, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Olivier Perrault, Mohamed Slaoui
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115535- (2023)
Identifying compounds that are neurotoxic either toward the central or the peripheral nervous systems (CNS or PNS) would greatly benefit early stages of drug development by derisking liabilities and selecting safe compounds. Unfortunately, so far ass
Externí odkaz:
https://doaj.org/article/efd0b2fddcb7403794d7295e4d4dd042
The Constitutive Activity of Spinal 5-HT6 Receptors Contributes to Diabetic Neuropathic Pain in Rats
Autor:
Nazarine Mokhtar, Marcin Drop, Florian Jacquot, Sylvain Lamoine, Eric Chapuy, Laetitia Prival, Youssef Aissouni, Vittorio Canale, Frédéric Lamaty, Paweł Zajdel, Philippe Marin, Stéphane Doly, Christine Courteix
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 364 (2023)
Diabetic neuropathy is often associated with chronic pain. Serotonin type 6 (5-HT6) receptor ligands, particularly inverse agonists, have strong analgesic potential and may be new candidates for treating diabetic neuropathic pain and associated co-mo
Externí odkaz:
https://doaj.org/article/daf7a7ff471b454c903b013b316013ce
Autor:
Stéphane Lolignier, Caroline Bonnet, Christelle Gaudioso, Jacques Noël, Jérôme Ruel, Muriel Amsalem, Jérémy Ferrier, Lise Rodat-Despoix, Valentine Bouvier, Youssef Aissouni, Laetitia Prival, Eric Chapuy, Françoise Padilla, Alain Eschalier, Patrick Delmas, Jérôme Busserolles
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 1067-1078 (2015)
Cold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood. Here, we show that the voltage-gated Nav1.9 sodium channel
Externí odkaz:
https://doaj.org/article/b41660b502d941c294543319bb5331b1
Autor:
Laetitia Prival, Emmanuel Bourinet, Jérôme Busserolles, Vanessa Pereira, David Balayssac, Sylvain Lamoine, Alain Eschalier, Anne Pizzoccaro, Mélissa Cuménal, Stéphane Lolignier, Youssef Aissouni
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
Molecular Neurobiology, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
Molecular Neurobiology, Humana Press, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
Molecular Neurobiology, 2021, 58 (7), pp.3575-3587. ⟨10.1007/s12035-021-02361-6⟩
International audience; Peripheral neuropathy is the most frequent dose-limiting adverse effect of oxaliplatin. Acute pain symptoms that are induced or exacerbated by cold occur in almost all patients immediately following the first infusions. Eviden
Autor:
Dimitra, Gkika, Stéphane, Lolignier, Guillaume P, Grolez, Alexis, Bavencoffe, Georges, Shapovalov, Dmitri, Gordienko, Artem, Kondratskyi, Mathieu, Meleine, Laetitia, Prival, Eric, Chapuy, Monique, Etienne, Alain, Eschalier, Yaroslav, Shuba, Roman, Skryma, Jérôme, Busserolles, Natalia, Prevarskaya
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
FASEB Journal, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
FASEB Journal, 2020, 34 (6), pp.7483-7499. ⟨10.1096/fj.201902270R⟩
International audience; Recent studies have revealed gender differences in cold perception, and pointed to a possible direct action of testosterone (TST) on the cold-activated TRPM8 (Transient Receptor Potential Melastatin Member 8) channel. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a3720930f75b7ae7d1f35c0cb881acbc
https://hal.uca.fr/hal-03512394
https://hal.uca.fr/hal-03512394
Autor:
Jérôme Busserolles, Laura Poupon, Youssef Aissouni, Stéphane Lolignier, Nicolas Authier, David Balayssac, Nicolas Kerckhove, David André Barrière, Fabrice Giraudet, Damien Richard, Michel Lazdunski, Alain Eschalier, Mathieu Meleine, Sylvain Lamoine, Vanessa Pereira, Laetitia Prival
Publikováno v:
Neuropharmacology
Neuropharmacology, Elsevier, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
Neuropharmacology, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
Neuropharmacology, Elsevier, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
Neuropharmacology, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩
International audience; Neurotoxicity remains the most common adverse effect of oxaliplatin, limiting its clinical use. In the present study, we developed a mouse model of chronic oxaliplatin-induced neuropathy, which mimics both sensory and motor de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8180b728beaf66f765518896817c4cd0
https://hal.archives-ouvertes.fr/hal-02065469
https://hal.archives-ouvertes.fr/hal-02065469
Autor:
Delphine, Vivier, Ismail Ben, Soussia, Nuno, Rodrigues, Stéphane, Lolignier, Maïly, Devilliers, Franck C, Chatelain, Laetitia, Prival, Eric, Chapuy, Geoffrey, Bourdier, Khalil, Bennis, Florian, Lesage, Alain, Eschalier, Jérôme, Busserolles, Sylvie, Ducki
Publikováno v:
Journal of medicinal chemistry. 60(3)
The TWIK-related K
Autor:
Nuno Rodrigues, Jérôme Busserolles, Sylvie Ducki, Florian Lesage, Eric Chapuy, Delphine Vivier, Geoffrey Bourdier, Alain Eschalier, Maïly Devilliers, Laetitia Prival, Khalil Bennis, Franck C. Chatelain, Ismail Ben Soussia, Stéphane Lolignier
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60, pp.1076-1088. ⟨10.1021/acs.jmedchem.6b01285⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (3), pp.1076-1088. ⟨10.1021/acs.jmedchem.6b01285⟩
Journal of Medicinal Chemistry, 2017, 60 (3), pp.1076-1088. ⟨10.1021/acs.jmedchem.6b01285⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60, pp.1076-1088. ⟨10.1021/acs.jmedchem.6b01285⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (3), pp.1076-1088. ⟨10.1021/acs.jmedchem.6b01285⟩
Journal of Medicinal Chemistry, 2017, 60 (3), pp.1076-1088. ⟨10.1021/acs.jmedchem.6b01285⟩
International audience; The TWIK-related K+ channel, TREK-1, has recently emerged as an attractive therapeutic target for the development of a novel class of analgesic drugs, suggesting that activation of TREK-1 could result in pain inhibition. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3165b40a9b3240f83e187aa02b3f1398
https://hal.archives-ouvertes.fr/hal-01540830
https://hal.archives-ouvertes.fr/hal-01540830