Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ladislav Habala"'
Autor:
Bianka Oboňová, Jindra Valentová, Miroslava Litecká, Ľudmila Pašková, Jana Hricovíniová, Andrea Bilková, František Bilka, Branislav Horváth, Ladislav Habala
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9166 (2024)
Several novel copper (II) complexes of reduced Schiff bases containing fluoride substituents were prepared and structurally characterized by single-crystal X-ray diffraction. The complexes exhibited diverse structures, with the central atom in distor
Externí odkaz:
https://doaj.org/article/c2992103ead448aeb3bd1755ad9c6ea8
Autor:
Bianka Oboňová, Ladislav Habala, Miroslava Litecká, Peter Herich, Andrea Bilková, František Bilka, Branislav Horváth
Publikováno v:
Life, Vol 13, Iss 7, p 1516 (2023)
A series of Schiff base ligands obtained by the condensation of trans-cyclohexane-1,2-diamine and fluorinated benzaldehydes were prepared, followed by their reduction with NaBH4. The reduced ligands were employed in the synthesis of zinc complexes of
Externí odkaz:
https://doaj.org/article/769c9486669745c8befdc664f0958a2f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5679 (2023)
Life is chiral, as its constituents consist, to a large degree, of optically active molecules, be they macromolecules (proteins, nucleic acids) or small biomolecules. Hence, these molecules interact disparately with different enantiomers of chiral co
Externí odkaz:
https://doaj.org/article/5bddac33c4c548ca8391c954ece7f07c
Publikováno v:
Molecules, Vol 25, Iss 12, p 2738 (2020)
Thanks to the progress made in chemical technology (particularly in the methodologies of stereoselective syntheses and analyses) along with regulatory measures, the number of new chiral drugs registered in the form of pure enantiomers has increased o
Externí odkaz:
https://doaj.org/article/53ad66c1e024488099e8527026e7398d
Publikováno v:
Applied Sciences, Vol 9, Iss 4, p 625 (2019)
The present survey concentrates on pharmacodynamics and pharmacokinetics of selected β-adrenergic blockers from the point of view of their stereochemistry. It could be shown that the activity in the arylaminoethanol and aryloxyaminopropanol group of
Externí odkaz:
https://doaj.org/article/b42893f963524d7f861bafb904351146
Autor:
Ladislav Habala, Samuel Varényi, Andrea Bilková, Peter Herich, Jindra Valentová, Jozef Kožíšek, Ferdinand Devínsky
Publikováno v:
Molecules, Vol 21, Iss 12, p 1742 (2016)
In order to evaluate the influence of substitution on biological properties of Schiff bases and their metal complexes, a series of differently substituted fluorine-containing Schiff bases starting from the drug isoniazid (isonicotinylhydrazide) were
Externí odkaz:
https://doaj.org/article/dcaee1dfbd31471698a03d3448292e37
Autor:
Horváth, Bianka Oboňová, Ladislav Habala, Miroslava Litecká, Peter Herich, Andrea Bilková, František Bilka, Branislav
Publikováno v:
Life; Volume 13; Issue 7; Pages: 1516
A series of Schiff base ligands obtained by the condensation of trans-cyclohexane-1,2-diamine and fluorinated benzaldehydes were prepared, followed by their reduction with NaBH4. The reduced ligands were employed in the synthesis of zinc complexes of
Publikováno v:
European Pharmaceutical Journal, Vol 67, Iss 2, Pp 34-44 (2021)
A homologous series of (3-alkoxymethyl-4-hydroxyphenyl)propan-1-ones was prepared by the reaction of (3-chloromethyl-4-hydroxyphenyl)propan-1-ones with the corresponding alcohols (methanol – decan-1-ol, propan-2-ol, 2-methylpropan-1-ol, 3-methylbut
Publikováno v:
European Pharmaceutical Journal, Vol 68, Iss 1, Pp 46-53 (2021)
Carboxylato-type transition metal complexes with agaric acid, a bioactive natural compound derived from citric acid, were prepared, and tested in vitro for their antimicrobial activity and cytotoxicity. The products as well as agaric acid itself are
Publikováno v:
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 70(1)
Since the advent of nitric oxide, diethyl ether, chloroform and cyclopropane, the greatest advancement in the area of general inhalational anesthetics has been achieved by the introduction of fluorinated anesthetics and the relevant chiral techniques