Výsledky vyhledávání - "Ladina Keller"

Akademický článek

Performance of the Kato-Katz method and real time polymerase chain reaction for the diagnosis of soil-transmitted helminthiasis in the framework of a randomised controlled trial: treatment efficacy and day-to-day variation

Autor: Ladina Keller, Chandni Patel, Sophie Welsche, Tobias Schindler, Eveline Hürlimann, Jennifer Keiser

Publikováno v: Parasites & Vectors, Vol 13, Iss 1, Pp 1-12 (2020)

Abstract Background Accurate, scalable and sensitive diagnostic tools are crucial in determining prevalence of soil-transmitted helminths (STH), assessing infection intensities and monitoring treatment efficacy. However, assessments on treatment effi

Externí odkaz: https://doaj.org/article/6b218f79df4b4f939d9ae40664b03fc3

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Akademický článek

Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with Trichuris trichiura: a randomized controlled trial protocol [version 2; peer review: 2 approved]

Autor: Sophie Welsche, Emmanuel C. Mrimi, Ladina Keller, Eveline Hürlimann, Daniela Hofmann, Jan Hattendorf, Said M. Ali, Jennifer Keiser

Publikováno v: Gates Open Research, Vol 5 (2021)

Background: Infections with soil-transmitted helminths (STHs) predominantly affect impoverished populations in tropical environments. The periodic administration of single dose benzimidazoles (i.e., albendazole, mebendazole) to at-risk individuals in

Externí odkaz: https://doaj.org/article/c3c346ae1f04449d8c2a1dc16f44fcbd

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Akademický článek

Long-term outcomes of ivermectin-albendazole versus albendazole alone against soil-transmitted helminths: Results from randomized controlled trials in Lao PDR and Pemba Island, Tanzania.

Autor: Ladina Keller, Sophie Welsche, Chandni Patel, Somphou Sayasone, Said M Ali, Shaali M Ame, Jan Hattendorf, Eveline Hürlimann, Jennifer Keiser

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009561 (2021)

BackgroundPreventive chemotherapy is the cornerstone of soil-transmitted helminth (STH) control. Long-term outcomes and adequate treatment frequency of the recently recommended albendazole-ivermectin have not been studied to date.Methodology/principa

Externí odkaz: https://doaj.org/article/9948b53cfdaf43ab99d3536859277200

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Akademický článek

Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with Trichuris trichiura: study protocol for a multi-country randomized controlled double-blind trial

Autor: Chandni Patel, Eveline Hürlimann, Ladina Keller, Jan Hattendorf, Somphou Sayasone, Said M Ali, Shaali M Ame, Jean T Coulibaly, Jennifer Keiser

Publikováno v: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-10 (2019)

Abstract Background Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended control strategy. Never

Externí odkaz: https://doaj.org/article/3f220e13cc69495ea185a1772b85168c

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Akademický článek

Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a case-control substudy conducted in Côte d'Ivoire, Lao PDR and Pemba Island, Tanzania

Autor: Chandni Patel, Ladina Keller, Sophie Welsche, Jan Hattendorf, Somphou Sayasone, Said M. Ali, Shaali M. Ame, Jean Tenena Coulibaly, Eveline Hürlimann, Jennifer Keiser

Publikováno v: EClinicalMedicine, Vol 32, Iss , Pp 100724- (2021)

Background: Infections with soil-transmitted helminths (STHs) may result in chronic inflammatory disorders affecting the human host. The objective of this study was to evaluate Fecal Calprotectin (FC) and Fecal Occult Blood (FOB) in individuals infec

Externí odkaz: https://doaj.org/article/2f96112d46f845b889052a5b45ff7999

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Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with Trichuris trichiura: a randomized controlled trial protocol

Autor: Daniela Hofmann, Eveline Hürlimann, Sophie Welsche, Jan Hattendorf, Jennifer Keiser, Said M. Ali, Ladina Keller, Emmanuel C Mrimi

Publikováno v: Gates Open Research

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b70f96ad55bd0f8681fc81489f2bd8
http://europepmc.org/articles/PMC8488464

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Long-term outcomes of ivermectin-albendazole versus albendazole alone against soil-transmitted helminths: Results from randomized controlled trials in Lao PDR and Pemba Island, Tanzania

Autor: Said M. Ali, Chandni Patel, Sophie Welsche, Ladina Keller, Jan Hattendorf, Eveline Hürlimann, Somphou Sayasone, Shaali M. Ame, Jennifer Keiser

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009561 (2021)

Background Preventive chemotherapy is the cornerstone of soil-transmitted helminth (STH) control. Long-term outcomes and adequate treatment frequency of the recently recommended albendazole-ivermectin have not been studied to date. Methodology/princi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bded6226c9274a9b7b7e9f9979fcdd5f
http://europepmc.org/articles/PMC8277064

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Autor: Jennifer Keiser, Jean T. Coulibaly, Said M. Ali, Somphou Sayasone, Jan Hattendorf, Eveline Hürlimann, Chandni Patel, Shaali M. Ame, Ladina Keller

Publikováno v: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Infectious Diseases

Background Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended control strategy. Nevertheless,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd5e20c3bad5be92390896bac471c9f
http://link.springer.com/article/10.1186/s12879-019-3882-x

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Efficacy and safety of co-administered ivermectin and albendazole in school-aged children and adults infected with Trichuris trichiura in Côte d'Ivoire, Laos, and Pemba Island, Tanzania: a double-blind, parallel-group, phase 3, randomised controlled trial

Autor: Said M. Ali, Eveline Hürlimann, Shaali M. Ame, Jan Hattendorf, Jennifer Keiser, Jean T. Coulibaly, Somphou Sayasone, Ladina Keller, Sophie Welsche, Chandni Patel

Publikováno v: The Lancet. Infectious diseases. 22(1)

BACKGROUND: Preventive chemotherapy with albendazole or mebendazole remains one of the cornerstones of soil-transmitted helminth control. However, these drugs are less effective against Trichuris trichiura. Combined ivermectin-albendazole is a promis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ff85058823498a440516ff92ee3314
https://pubmed.ncbi.nlm.nih.gov/34856182

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Insights gained from conducting a randomised controlled trial on Ivermectin-Albendazole against Trichuris trichiura in Côte d'Ivoire, Lao PDR and Pemba Island

Autor: Ladina, Keller, Eveline, Hürlimann, Chandni, Patel, Sophie, Welsche, Somphou, Sayasone, Said M, Ali, Shaali M, Ame, Jean Tenena, Coulibaly, Jennifer, Keiser

Publikováno v: Advances in parasitology. 111

There is only limited scientific literature on trial methodology, trial procedures and mitigation strategies to overcome challenges faced during clinical research taking place in resource constrained healthcare environments. Organisational, cultural,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3267ca6d2caa960814aef5e816be20cd
https://pubmed.ncbi.nlm.nih.gov/33482976

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