Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ladan Parhamifar"'
Autor:
Arjen Weller, Morten B. Hansen, Rodolphe Marie, Adam C. Hundahl, Casper Hempel, Paul J. Kempen, Henrik L. Frandsen, Ladan Parhamifar, Jannik B. Larsen, Thomas L. Andresen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Unsuccessful clinical translation of orally delivered biological drugs remains a challenge in pharmaceutical development and has been linked to insufficient mechanistic understanding of intestinal drug transport. Live cell imaging could provide such
Externí odkaz:
https://doaj.org/article/e425fcb8956a43f1a5293643c45fd42a
Publikováno v:
BioImpacts, Vol 3, Iss 1, Pp 1-4 (2013)
Unlike conventional antibodies, heavy chain only antibodies derived from camel contain a single variable domain (VHH) and two constant domains (CH2 and CH3). Cloned and isolated VHHs possess unique properties that enable them to excel conventional th
Externí odkaz:
https://doaj.org/article/6a2128123cb24bdf99d1affe48a2c4fb
Autor:
Sasan Nazemi, Mette Rahbek, Ladan Parhamifar, Seyed Moein Moghimi, Hamid Babamoradi, Foojan Mehrdana, Dan Arne Klærke, Christopher H Knight
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106809 (2014)
Milk secretion involves significant flux of water, driven largely by synthesis of lactose within the Golgi apparatus. It has not been determined whether this flux is simply a passive consequence of the osmotic potential between cytosol and Golgi, or
Externí odkaz:
https://doaj.org/article/959a8f32dd4a4be6885c67fbd6a9de8d
Autor:
Ladan Parhamifar, Wondossen Sime, Yuliana Yudina, Frederik Vilhardt, Matthias Mörgelin, Anita Sjölander
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14439 (2010)
BackgroundLeukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly through two different G-protein-c
Externí odkaz:
https://doaj.org/article/2593142dbc78474f9adb0162f902233c
Autor:
Rasmus Münter, Martin Bak, Esben Christensen, Paul J. Kempen, Jannik B. Larsen, Kasper Kristensen, Ladan Parhamifar, Thomas L. Andresen
Publikováno v:
Acta Biomaterialia. 144:96-108
Stimulation of monocytes with immunomodulating agents can harness the immune system to treat a long range of diseases, including cancers, infections and autoimmune diseases. To this end we aimed to develop a monocyte-targeting delivery platform based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efd93902ae3dc9d4952e219adeccd1f
https://doi.org/10.1016/j.actbio.2022.03.029
https://doi.org/10.1016/j.actbio.2022.03.029
Autor:
Camilla Stavnsbjerg, Esben Christensen, Rasmus Münter, Jonas R. Henriksen, Matthias Fach, Ladan Parhamifar, Camilla Christensen, Andreas Kjaer, Anders E. Hansen, Thomas L. Andresen
Publikováno v:
Stavnsbjerg, C, Christensen, E, Münter, R, Henriksen, J R, Fach, M, Parhamifar, L, Christensen, C, Kjaer, A, Hansen, A E & Andresen, T L 2022, ' Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists ', Journal of controlled release, vol. 342, pp. 337-344 . https://doi.org/10.1016/j.jconrel.2021.12.033
Systemic administration of toll-like receptor (TLR) agonists have demonstrated impressive preclinical results as an anti-cancer therapy due to their potent innate immune-stimulatory properties. The clinical advancement has, however, been hindered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617c818b4e1fea03f053b99581939a5c
https://doi.org/10.1016/j.jconrel.2021.12.033
https://doi.org/10.1016/j.jconrel.2021.12.033
Publikováno v:
Molecular Pharmaceutics. 16:2462-2469
Delivering peptides and proteins with intracellular function represents a promising avenue for therapeutics, but remains a challenge due to the selective permeability of the plasma membrane. The successful delivery of cytosolically active proteins wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79d18023d8ae57487ea64ab4aa2446e
https://doi.org/10.1021/acs.molpharmaceut.9b00070
https://doi.org/10.1021/acs.molpharmaceut.9b00070
Publikováno v:
Journal of Controlled Release. 244:24-29
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. It has been questioned as to whether polyplexes in the cytoplasm can reach the nuclear compartment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e92cde1787143182a3de8cd8483b65
https://doi.org/10.1016/j.jconrel.2016.11.008
https://doi.org/10.1016/j.jconrel.2016.11.008
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1943
Cellular toxicity and/or cell death entail complex mechanisms that require detailed evaluation for proper characterization. A detailed mechanistic assessment of cytotoxicity is essential for design and construction of more effective polycations for n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4c19d056bbb0dfa3d2596eecd9193857
https://pubmed.ncbi.nlm.nih.gov/30838623
https://pubmed.ncbi.nlm.nih.gov/30838623
Publikováno v:
Nanotechnology for Nucleic Acid Delivery ISBN: 9781493990917
Nanotechnology for Nucleic Acid Delivery ISBN: 9781627031394
Nanotechnology for Nucleic Acid Delivery ISBN: 9781627031394
Cellular toxicity and/or cell death entail complex mechanisms that require detailed evaluation for proper characterization. A detailed mechanistic assessment of cytotoxicity is essential for design and construction of more effective polycations for n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77166626f21dde5d417496eb7deff81e
https://doi.org/10.1007/978-1-4939-9092-4_18
https://doi.org/10.1007/978-1-4939-9092-4_18
