Výsledky vyhledávání - "Ladam, Franck"

Dissertation/ Thesis

Etude du rôle du facteur de transcription Pea3 pendant la morphogenèse et la tumorigenèse mammaires : caractérisation de ses propriétés pro-morphogènes et pro-tumorigènes : étude des mécanismes moléculaires associés

Autor: Ladam, Franck

Les Facteurs de transcription du groupe PEA3 (Pea3, Erm et Er81) font partie de la famille d’oncogènes ETS. Leur expression est souvent observée lors de la mise en place des organes par morphogenèse de branchement tels que les poumons ou encore

Externí odkaz: http://www.theses.fr/2010LIL2S031/document

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Akademický článek

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Additional file 7: of ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-Lelièvre, Anne

Figure S5. Expression of ETV4 in MMT-shMMP13-repressing cells. a Relative ETV4 mRNA expression in the MMT-ETV4 + shCtrl and MMT-ETV4 + shMMP13 cells determined by real-time PCR and normalized to cyclophilin A levels. mRNA expression in MMT-Ctrl + shC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a0ae06c198bdea49e2762994f0894e

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Additional file 6: of ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-Lelièvre, Anne

Figure S4. Expression of MMP13 in MMT cells overexpressing or repressing MMP13. a and b Relative MMP13 mRNA expression in the MMT-Ctrl and MMT-MMP13 (a) or MMT-shCtrl and MMT-shMMP13 cells (b) determined by real-time PCR and normalized to cyclophilin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ab38f70d4d3fd9766f1fbfa3d42719

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Additional file 5: of ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, BiĂ¨Che, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-LeliĂ¨Vre, Anne

Figure S3. ChIP experiment for ETV4 and MMP13 in MMT and TAC cells. PCR detection of the MMP13 promoter region after ETV4 immunoprecipitation in MMT-ETV4 (left panel) and TAC-ETV4 (right panel). Primers allowing the amplification of the proximal MMP1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27355ba3c8de2f3133db1f08a429623a

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Additional file 8: of ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-Lelièvre, Anne

Figure S6. The repression of MMP13 reduces the anchorage-independent growth capacity of MMT-ETV4-overexpressing cells. a Relative MMP13 mRNA expression in the transiently transfected MMT-siCtrl and MMT-siMMP13 cells determined by real-time PCR and no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b265b9f5f84733a9b97d61fcc2da010b

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Additional file 4: of ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, BiĂ¨Che, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-LeliĂ¨Vre, Anne

Figure S2. ETS and AP-1 binding sites are highly conserved among mouse, human, and rabbit. Nucleotide sequence comparison of mouse, human, and rat proximal MMP13 promoters. Shaded boxes indicate the conserved ETS and AP-1 binding site sequences. (PDF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a9728bfdb5d1469a0477f63929f5b0

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ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, De Launoit, Yvan, Tulasne, David, Chotteau-Lelièvre, Anne

Publikováno v: Breast Cancer Research
Breast Cancer Research, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20, ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, Vol 20, Iss 1, Pp 1-18 (2018)
Breast Cancer Research : BCR
Breast Cancer Research, BioMed Central, 2018, 20 (1), ⟨10.1186/s13058-018-0992-0⟩

Background The ETS transcription factor ETV4 is involved in the main steps of organogenesis and is also a significant mediator of tumorigenesis and metastasis, such as in breast cancer. Indeed, ETV4 is overexpressed in breast tumors and is associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1bdbc6fa24e5fe30ccd6083e8937deb
https://hal.science/hal-02391607

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