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Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-Lelièvre, Anne
Figure S5. Expression of ETV4 in MMT-shMMP13-repressing cells. a Relative ETV4 mRNA expression in the MMT-ETV4 + shCtrl and MMT-ETV4 + shMMP13 cells determined by real-time PCR and normalized to cyclophilin A levels. mRNA expression in MMT-Ctrl + shC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a0ae06c198bdea49e2762994f0894e
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-Lelièvre, Anne
Figure S4. Expression of MMP13 in MMT cells overexpressing or repressing MMP13. a and b Relative MMP13 mRNA expression in the MMT-Ctrl and MMT-MMP13 (a) or MMT-shCtrl and MMT-shMMP13 cells (b) determined by real-time PCR and normalized to cyclophilin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ab38f70d4d3fd9766f1fbfa3d42719
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, BièChe, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-LelièVre, Anne
Figure S3. ChIP experiment for ETV4 and MMP13 in MMT and TAC cells. PCR detection of the MMP13 promoter region after ETV4 immunoprecipitation in MMT-ETV4 (left panel) and TAC-ETV4 (right panel). Primers allowing the amplification of the proximal MMP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27355ba3c8de2f3133db1f08a429623a
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, BièChe, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-LelièVre, Anne
Table S1. Pathological and clinical characteristics of patients in relation to metastasis-free survival (MFS). (PDF 33 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c07ceeee6443f3707ddfddc3d1f2ee6
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, BièChe, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-LelièVre, Anne
Table S2. Multivariate Cox proportional hazards analysis of MFS for MMP13 and ETV4 expression levels in the series of 456 breast tumors. (PDF 42 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48101e34608de08a296b7b299a66edba
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-Lelièvre, Anne
Figure S6. The repression of MMP13 reduces the anchorage-independent growth capacity of MMT-ETV4-overexpressing cells. a Relative MMP13 mRNA expression in the transiently transfected MMT-siCtrl and MMT-siMMP13 cells determined by real-time PCR and no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b265b9f5f84733a9b97d61fcc2da010b
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, BièChe, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-LelièVre, Anne
Figure S2. ETS and AP-1 binding sites are highly conserved among mouse, human, and rabbit. Nucleotide sequence comparison of mouse, human, and rat proximal MMP13 promoters. Shaded boxes indicate the conserved ETS and AP-1 binding site sequences. (PDF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a9728bfdb5d1469a0477f63929f5b0
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, De Launoit, Yvan, Tulasne, David, Chotteau-Lelièvre, Anne
Publikováno v:
Breast Cancer Research
Breast Cancer Research, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20, ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, Vol 20, Iss 1, Pp 1-18 (2018)
Breast Cancer Research : BCR
Breast Cancer Research, BioMed Central, 2018, 20 (1), ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20, ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, Vol 20, Iss 1, Pp 1-18 (2018)
Breast Cancer Research : BCR
Breast Cancer Research, BioMed Central, 2018, 20 (1), ⟨10.1186/s13058-018-0992-0⟩
Background The ETS transcription factor ETV4 is involved in the main steps of organogenesis and is also a significant mediator of tumorigenesis and metastasis, such as in breast cancer. Indeed, ETV4 is overexpressed in breast tumors and is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1bdbc6fa24e5fe30ccd6083e8937deb
https://hal.science/hal-02391607
https://hal.science/hal-02391607
Autor:
Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, Launoit, Yvan De, Tulasne, David, Chotteau-Lelièvre, Anne
Figure S1. Validation of the overexpression of ETV4 and MMP13 in MCF10A cells. a and b Relative ETV4 mRNA (a) and MMP13 mRNA (b) expression in the MCF10A-Ctrl and MCF10A-ETV4 cells determined by real-time PCR and normalized to cyclophilin A levels. m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb5b85267de1922a1abf3547659a436