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pro vyhledávání: '"Lacy Butler"'
Autor:
James Hepler, Chaokun Li, Manisha Kapoor, Lacy Butler, Yongchang Chang, Max Marty, Ivan Smirnov, Mitsitoshi Nakada, Anna Joy, Acacia Crouch, Joseph Georges, Burt G. Feuerstein
Publikováno v:
Journal of neuro-oncology, vol 130, iss 1
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node in the pathway, has 3 isoforms, AKT1, AKT2 and AKT3. Here we investigate their role in GBM. We find each activated, ser473