Enhanced Anti-Inflammatory Effect of the Combination of Lactiplantibacillus plantarum LS/07 with Methotrexate Compared to Their Monotherapies Studied in Experimental Arthritis

Autor: Katarína Pružinská, Lukáš Slovák, František Dráfi, Silvester Poništ, Ivo Juránek, Martin Chrastina, Karol Švík, Ladislav Strojný, Ľuboš Ambro, Katarína Bauerová

Publikováno v: Molecules, Vol 28, Iss 1, p 297 (2022)

The gut microbiome (GM) of rheumatic arthritis (RA) patients is often altered in composition and function. Moreover, methotrexate (MTX), one of the most frequently used disease-modifying antirheumatic drugs, is known to negatively affect GM compositi

Externí odkaz: https://doaj.org/article/7e61c86a08e2463688b67ee9b6c2e3a1

Enhanced Anti-Inflammatory Effect of the Combination of Lactiplantibacillus plantarum LS/07 with Methotrexate Compared to Their Monotherapies Studied in Experimental Arthritis.

Autor: Pružinská K; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.; Jessenius Faculty of Medicine in Martin, Comenius University, Malá Hora 4A, 03601 Martin, Slovakia., Slovák L; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia., Dráfi F; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia., Poništ S; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia., Juránek I; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia., Chrastina M; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.; Jessenius Faculty of Medicine in Martin, Comenius University, Malá Hora 4A, 03601 Martin, Slovakia., Švík K; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia., Strojný L; Center of Clinical and Preclinical Research, Faculty of Medicine, Pavol Jozef Šafárik University, Trieda SNP 1, 04011 Košice, Slovakia., Ambro Ľ; Center for Interdisciplinary Biosciences, Technology and Innovation Park, Pavol Jozef Šafárik University, Jesenná 5, 04001 Košice, Slovakia., Bauerová K; Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 30; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 30.