The GK rat beta-cell: A prototype for the diseased human beta-cell in type 2 diabetes?

Autor: Portha, B., Lacraz, G., Kergoat, M., Homo-Delarche, F., Giroix, M.-H., Bailbé, D., Gangnerau, M.-N., Dolz, M., Tourrel-Cuzin, C., Movassat, J.

Publikováno v: In Molecular and Cellular Endocrinology 2009 297(1):73-85

The prediabetic period is characterized by islet microangiopathy in the Goto-Kakizaki rat, a spontaneous model of type 2 diabetes

Autor: Homo-Delarche, Françoise, Giroix, M.H., Lacraz, G., Calderari, Sophie, Cornut, M., Ehses, J.A., Schmidlin, F., Coulaud, J., Gangnerau, M.N., Serradas, P., Irminger, J.C.

Publikováno v: 44. EASD Annual Meeting of the European Association for the Study of Diabetes
44. EASD Annual Meeting of the European Association for the Study of Diabetes, Sep 2008, Rome, Italy. Springer, Diabetologia, 51 (S1), 588 p., 2008, 44th EASD Annual Meeting of the European Association for the Study of Diabetes

International audience; Endothelial signals are essential during pancreas development. Goto-Kakizaki (GK) rats have a 70% decrease in β-cell mass at E18, while it is similar at E13 to that of Wistar control rats. Because adult diabetic GK rats are h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e015c61f739ea7662ec6753cb9e1c6ca
https://hal.inrae.fr/hal-02755329

P255 A PATHOGENIC ROLE FOR IL-15 IN FATTY LIVER DISEASE

Autor: Cepero-Donates, Y., Lacraz, G., Mayhue, M., Ramanathan, S., Ilangumaran, S.

Publikováno v: In Journal of Hepatology April 2014 60(1) Supplement:S150-S150

Defective functional β-cell mass and Type 2 diabetes in the Goto--Kakizaki rat model.

Autor: Portha, Bernard, Lacraz, G., Dolz, M., Homo-Delarche, F., Giroix, M.-H., Movassat, J.

Publikováno v: Expert Review of Endocrinology & Metabolism; Nov2007, Vol. 2 Issue 6, p785-795, 11p, 1 Color Photograph, 2 Diagrams, 3 Graphs

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