Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lachlan P.G. Wheeler"'
Autor:
Alysia Fogliani, Imke G. J. Houwers, Lachlan P.G. Wheeler, Jun Han Yoon, Danii Baron-Heeris, Emmanuel A. Akinpelu, Emma Duce, Bernadette T. Majda, Sreya Santhakumar, Tylie M. Wiseman, Alan R. Harvey, Sarah J. Lovett, Brooke Fehily, Stuart I. Hodgetts, Margaret A. Pollett
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) in motor-related regions of the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d23e6ba33a3df602fb854de36c14706
https://doaj.org/article/1a8b0e65624940cbb9fcbfda79c855ba
https://doaj.org/article/1a8b0e65624940cbb9fcbfda79c855ba
Autor:
Chrisna J. LeVaillant, Greg Cozens, Jennifer Rodger, Anil Sharma, Lachlan P.G. Wheeler, Alan R. Harvey, Jill Muhling, Mats Hellström
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Use of viral vectors to deliver therapeutic genes to the central nervous system holds promise for the treatment of neurodegenerative diseases and neurotrauma. Adeno-associated viral (AAV) vectors encoding brain-derived neurotrophic factor (BDNF) or c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7127fd3f67f54f11b5801a083494e9d8
http://www.sciencedirect.com/science/article/pii/S2329050117300360
http://www.sciencedirect.com/science/article/pii/S2329050117300360
Autor:
Sarah J. Lovett, Bernadette T. Majda, Stuart I. Hodgetts, Alan R. Harvey, Jun H. Yoon, Lachlan P.G. Wheeler
Publikováno v:
Brain research. 1619
A variety of neurotrophic factors have been used in attempts to improve morphological and behavioural outcomes after experimental spinal cord injury (SCI). Here we review many of these factors, their cellular targets, and their therapeutic impact on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec0d6705fad7586928cadfde65f2ecd
https://pubmed.ncbi.nlm.nih.gov/25451132
https://pubmed.ncbi.nlm.nih.gov/25451132
Autor:
Lachlan P.G. Wheeler, Marcus K. Giacci, Robert Vink, Melinda Fitzgerald, Riccardo Natoli, Bernadette T. Majda, Corinna van den Heuvel, Elizabeth Harford-Wright, Jan Provis, Emma J. Dishington, Alan R. Harvey, Sarah A. Dunlop, Emma Thornton, Sarah J. Lovett, Stuart I. Hodgetts, Nathan S. Hart, Carole A. Bartlett, Anna V. Leonard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 8, p e104565 (2014)
PLoS ONE, Vol 9, Iss 8, p e104565 (2014)
Red/near-infrared irradiation therapy (R/NIR-IT) delivered by laser or light-emitting diode (LED) has improved functional outcomes in a range of CNS injuries. However, translation of R/NIR-IT to the clinic for treatment of neurotrauma has been hamper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967faf195afa68c0e85887c15367ad1d
http://europepmc.org/articles/PMC4126771
http://europepmc.org/articles/PMC4126771
Autor:
Chrisna J. LeVaillant, Greg Cozens, Alan R. Harvey, Marisa Ryan, Jennifer Rodger, Lachlan P.G. Wheeler, Anne S. Kramer, Colette Moses, Margaret A. Pollett, Anil Sharma
Publikováno v:
eNeuro
Similar to neurons in the peripheral nervous system, immature CNS-derived RGCs become dependent on target-derived neurotrophic support as their axons reach termination sites in the brain. To study the factors that influence this developmental transit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd294d899cf34371f34c1af29cf5bbdc
https://doi.org/10.1523/eneuro.0044-14.2015
https://doi.org/10.1523/eneuro.0044-14.2015