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pro vyhledávání: '"Lachlan Molony"'
Autor:
John Babiak, Nicole Risher, Marla Weetall, Diksha Kaushik, Shirley Yeh, Kylie O'Keefe, Valerie Northcutt, Ronald Kong, Young-Choon Moon, Ellen Welch, Lachlan Molony, Jiyuan Ma
Publikováno v:
Xenobiotica. 52:152-164
Emvododstat was identified as a potent inhibitor of dihydroorotate dehydrogenase and is now in clinical development for the treatment of acute myeloid leukaemia and COVID-19. The objective of this paper is to evaluate the metabolism, pharmacokinetics