Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lachlan M. McDowall"'
Publikováno v:
HeartRhythm Case Reports
The management of malignancy with immunotherapy is a rapidly evolving field and immune checkpoint inhibitors (ICI) are being used and trialed in an increasing number of malignancies. Monoclonal antibodies that target programmed death-1 (PD-1) and cyt
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 299:R853-R861
The midbrain periaqueductal gray (PAG) mediates the physiological responses to a wide range of stressors. It consists of four longitudinal columns that have different anatomical connections and functional properties. Previous anatomical and behaviora
Publikováno v:
The Journal of Physiology. 587:5149-5162
Activation of neurons in the dorsomedial hypothalamus (DMH) evokes increases in mean arterial pressure (MAP), sympathetic activity, heart rate (HR) and respiratory activity. Results of previous studies suggest that the DMH-evoked increases in MAP and
Publikováno v:
Autonomic Neuroscience. 142:71-76
The dorsomedial hypothalamus (DMH) is an essential brain region for the integration of the physiological response to psychological stressors. The cardiovascular components of the response include increases in blood pressure, heart rate and the activi
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 293:R1728-R1735
Neurons within the dorsomedial hypothalamus (DMH) play a critical role in subserving the cardiovascular and neuroendocrine response to psychological stress. An increase in respiratory activity is also a characteristic feature of the physiological res
DIFFERENTIAL CONTROL OF CARDIAC AND SYMPATHETIC VASOMOTOR ACTIVITY FROM THE DORSOMEDIAL HYPOTHALAMUS
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 33:1265-1268
1. The dorsomedial hypothalamus (DMH) plays a crucial role in mediating the cardiovascular responses to different stressors, including acute psychological stress and cold stress. Activation of neurons in the DMH evokes increases in arterial pressure
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H2003-H2007
The logistic sigmoid function curve provides an accurate description of the baroreflex input-output relationship and is the most commonly used equation for this purpose. The threshold (Thr) and saturation (Sat) values for the baroreflex are commonly
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 290:R1020-R1026
Neurons within the dorsomedial hypothalamic nucleus (DMH) and perifornical area (PeF), which lie within the classic hypothalamic defense area, subserve the cardiovascular response to psychological stress. Previous studies have shown that electrical s
Autor:
Lachlan M. McDowall, M. J. Sheriff, Roger A. L. Dampney, Suzanne Killinger, Jouji Horiuchi, Peter S. P. Tan
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 32:419-425
1. The long-term level of arterial pressure is dependent on the relationship between arterial pressure and the urinary output of salt and water, which, in turn, is affected by a number of factors, including renal sympathetic nerve activity (RSNA). In
Publikováno v:
The European journal of neuroscience. 39(9)
Psychological stress evokes increases in sympathetic activity and blood pressure, which are due at least in part to an upward resetting of the baroreceptor-sympathetic reflex. In this study we determined whether sympathetic premotor neurons in the ro