Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Lacey R McNally"'
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 9, p e1003231 (2013)
A clear contradiction exists between cytotoxic in-vitro studies demonstrating effectiveness of Gemcitabine to curtail pancreatic cancer and in-vivo studies failing to show Gemcitabine as an effective treatment. The outcome of chemotherapy in metastat
Externí odkaz:
https://doaj.org/article/f7cf1236a17e4ce5b4e9dccba496877c
Autor:
Zheng Han, William M. MacCuaig, Metin N. Gurcan, Juan Claros-Sorto, Tabitha Garwe, Christina Henson, Jennifer Holter-Chakrabarty, Bethany Hannafon, Vishal Chandra, Elizabeth Wellberg, Lacey R. McNally
Publikováno v:
Photoacoustics, Vol 32, Iss , Pp 100531- (2023)
Clinical tools for measuring tumor vascular hemodynamics, such as dynamic contrast-enhanced MRI, are clinically important to assess tumor properties. Here we explored the use of multispectral optoacoustic tomography (MSOT), which has a high spatial a
Externí odkaz:
https://doaj.org/article/ad26c02137cb4a2584c37990fbc63ffb
Autor:
Matthew D. Laramie, Benjamin L. Fouts, William M. MacCuaig, Emmanuel Buabeng, Meredith A. Jones, Priyabrata Mukherjee, Bahareh Behkam, Lacey R. McNally, Maged Henary
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Optoacoustic imaging is a new biomedical imaging technology with clear benefits over traditional optical imaging and ultrasound. While the imaging technology has improved since its initial development, the creation of dedicated contrast agen
Externí odkaz:
https://doaj.org/article/a1050fb86c204867a017ee7d6fe47964
Publikováno v:
Advanced Intelligent Systems, Vol 4, Iss 3, Pp n/a-n/a (2022)
Bacteria‐mediated drug delivery systems comprising nanotherapeutics conjugated onto bacteria synergistically augment the efficacy of both therapeutic modalities in cancer therapy. Nanocarriers preserve therapeutics’ bioavailability and reduce sys
Externí odkaz:
https://doaj.org/article/021263c194fd45f38144898bdaabca00
Publikováno v:
Photoacoustics, Vol 13, Iss , Pp 46-52 (2019)
While particle carriers have potential to revolutionize disease treatment, using these carriers requires knowledge of spatial and temporal biodistribution. The goal of this study was to track orally administered particle uptake and trafficking throug
Externí odkaz:
https://doaj.org/article/a23e8f26202e413384e12728924ce588
Autor:
Zhijun Zhou, Junxia Zhang, Chao Xu, Jingxuan Yang, Yuqing Zhang, Mingyang Liu, Xiuhui Shi, Xiaoping Li, Hanxiang Zhan, Wei Chen, Lacey R. McNally, Kar-Ming Fung, Wenyi Luo, Courtney W. Houchen, Yulong He, Changhua Zhang, Min Li
Publikováno v:
EBioMedicine, Vol 65, Iss , Pp 103271- (2021)
Background: N6-methyladenosine (m6A) is the most abundant mRNA modification. Whether m6A regulators can determine tumor aggressiveness and risk of immune evasion in pancreatic ductal adenocarcinoma (PDAC) remains unknown. Methods: An integrated model
Externí odkaz:
https://doaj.org/article/45f0db65785742de978653edca4a8884
Autor:
Ted G. Xiao, Jared A. Weis, F. Scott Gayzik, Alexandra Thomas, Akiko Chiba, Metin N. Gurcan, Umit Topaloglu, Abhilash Samykutty, Lacey R. McNally
Publikováno v:
Photoacoustics, Vol 11, Iss , Pp 28-35 (2018)
Examining the dynamics of an agent in the tumor microenvironment can offer critical insights to the influx rate and accumulation of the agent. Intratumoral kinetic characterization in the in vivo setting can further elicudate distribution patterns an
Externí odkaz:
https://doaj.org/article/ccb21c3213e045faa54cb4da544f1d56
Autor:
Clinton W. Hupple, Stefan Morscher, Neal C. Burton, Mark D. Pagel, Lacey R. McNally, Julio Cárdenas-Rodríguez
Publikováno v:
Photoacoustics, Vol 10, Iss , Pp 54-64 (2018)
MultiSpectral Optoacoustic Tomography (MSOT) is an emerging imaging technology that allows for data acquisition at high spatial and temporal resolution. These imaging characteristics are advantageous for Dynamic Contrast Enhanced (DCE) imaging that c
Externí odkaz:
https://doaj.org/article/cc3081c9f6b44b70b94e5d3d582bc53a
Autor:
Abhilash Samykutty, Karl N. Thomas, Molly McNally, Jordan Hagood, Akiko Chiba, Alexandra Thomas, Libby McWilliams, Bahareh Behkam, Ying Zhan, McAlister Council-Troche, Juan C. Claros-Sorto, Christina Henson, Tabitha Garwe, Zoona Sarwar, William E. Grizzle, Lacey R. McNally
Publikováno v:
Radiol Imaging Cancer
PURPOSE: To develop optoacoustic, spectrally distinct, actively targeted gold nanoparticle–based near-infrared probes (trastuzumab [TRA], TRA-Aurelia-1, and TRA-Aurelia-2) that can be individually identifiable at multispectral optoacoustic tomograp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5598c7dd6f1e38d5793cd95f10024f18
https://doi.org/10.1148/rycan.220180
https://doi.org/10.1148/rycan.220180
Autor:
Meredith A. Jones, William M. MacCuaig, Alex N. Frickenstein, Seda Camalan, Metin N. Gurcan, Jennifer Holter-Chakrabarty, Katherine T. Morris, Molly W. McNally, Kristina K. Booth, Steven Carter, William E. Grizzle, Lacey R. McNally
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 152 (2021)
Inflammatory diseases include a wide variety of highly prevalent conditions with high mortality rates in severe cases ranging from cardiovascular disease, to rheumatoid arthritis, to chronic obstructive pulmonary disease, to graft vs. host disease, t
Externí odkaz:
https://doaj.org/article/dff897f0ec9b46468782c43c0676215e