Zobrazeno 1 - 10
of 1 343
pro vyhledávání: '"Lacey E"'
Autor:
Lacey E. Hankin, Chad T. Anderson
Publikováno v:
Forests, Vol 15, Iss 7, p 1190 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/f75144291fc946f5ba8557e8e4065abd
Autor:
Emel Alkim, Heidi Dowst, Julie DiCarlo, Lacey E. Dobrolecki, Anadulce Hernández-Herrera, David A. Hormuth, Yuxing Liao, Apollo McOwiti, Robia Pautler, Mothaffar Rimawi, Ashley Roark, Ramakrishnan Rajaram Srinivasan, Jack Virostko, Bing Zhang, Fei Zheng, Daniel L. Rubin, Thomas E. Yankeelov, Michael T. Lewis
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 810-828 (2023)
Co-clinical trials are the concurrent or sequential evaluation of therapeutics in both patients clinically and patient-derived xenografts (PDX) pre-clinically, in a manner designed to match the pharmacokinetics and pharmacodynamics of the agent(s) us
Externí odkaz:
https://doaj.org/article/e0d87f8b7a8e4f92951123a867d724ef
Autor:
Donna M. Peehl, Cristian T. Badea, Thomas L. Chenevert, Heike E. Daldrup-Link, Li Ding, Lacey E. Dobrolecki, A. McGarry Houghton, Paul E. Kinahan, John Kurhanewicz, Michael T. Lewis, Shunqiang Li, Gary D. Luker, Cynthia X. Ma, H. Charles Manning, Yvonne M. Mowery, Peter J. O'Dwyer, Robia G. Pautler, Mark A. Rosen, Raheleh Roudi, Brian D. Ross, Kooresh I. Shoghi, Renuka Sriram, Moshe Talpaz, Richard L. Wahl, Rong Zhou
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 657-680 (2023)
The availability of high-fidelity animal models for oncology research has grown enormously in recent years, enabling preclinical studies relevant to prevention, diagnosis, and treatment of cancer to be undertaken. This has led to increased opportunit
Externí odkaz:
https://doaj.org/article/315dd791b13b4c40966ef7abc8d61d4c
Autor:
Oscar D Murillo, Varduhi Petrosyan, Emily L LaPlante, Lacey E Dobrolecki, Michael T Lewis, Aleksandar Milosavljevic
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011365 (2023)
Proper characterization of cancer cell states within the tumor microenvironment is a key to accurately identifying matching experimental models and the development of precision therapies. To reconstruct this information from bulk RNA-seq profiles, we
Externí odkaz:
https://doaj.org/article/006f994a827e452db20048595c03626a
Autor:
Varduhi Petrosyan, Lacey E. Dobrolecki, Emily L. LaPlante, Ramakrishnan Rajaram Srinivasan, Matthew H. Bailey, Alana L. Welm, Bryan E. Welm, Michael T. Lewis, Aleksandar Milosavljevic
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-5 (2022)
Abstract TNBC is a heterogeneous subtype of breast cancer, and only a subset of TNBC can be established as PDXs. Here, we show that there is an engraftment bias toward TNBC with low levels of immune cell infiltration. Additionally, TNBC that failed t
Externí odkaz:
https://doaj.org/article/df1189d5619f478396baf68cd383f8f1
RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer
Autor:
Marina Ciscar, Eva M Trinidad, Gema Perez‐Chacon, Mansour Alsaleem, Maria Jimenez, Maria J Jimenez‐Santos, Hector Perez‐Montoyo, Adrian Sanz‐Moreno, Andrea Vethencourt, Michael Toss, Anna Petit, Maria T Soler‐Monso, Victor Lopez, Jorge Gomez‐Miragaya, Clara Gomez‐Aleza, Lacey E Dobrolecki, Michael T Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela‐Fandino, Fatima Al‐Shahrour, Antonio Martinez‐Aranda, Angels Sierra, Andrew R Green, Emad Rakha, Eva Gonzalez‐Suarez
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract Despite strong preclinical data, the therapeutic benefit of the RANKL inhibitor, denosumab, in breast cancer patients, beyond the bone, is unclear. Aiming to select patients who may benefit from denosumab, we hereby analyzed RANK and RANKL p
Externí odkaz:
https://doaj.org/article/1a7e932a6a184ce6a384d4a58e43a0be
Publikováno v:
International Journal of Child Care and Education Policy, Vol 16, Iss 1, Pp 1-22 (2022)
Abstract This study examines how policy directives and recommendations implemented during a massive universal Pre-Kindergarten expansion in New York City has impacted teachers’ professional identity. We adapted the critical ecologies of the early c
Externí odkaz:
https://doaj.org/article/d50ce5f16afe4342a7c7787bdd07cf09
Autor:
Varduhi Petrosyan, Lacey E. Dobrolecki, Lillian Thistlethwaite, Alaina N. Lewis, Christina Sallas, Ramakrishnan R. Srinivasan, Jonathan T. Lei, Vladimir Kovacevic, Predrag Obradovic, Matthew J. Ellis, C. Kent Osborne, Mothaffar F. Rimawi, Anne Pavlick, Maryam Nemati Shafaee, Heidi Dowst, Antrix Jain, Alexander B. Saltzman, Anna Malovannaya, Elisabetta Marangoni, Alana L. Welm, Bryan E. Welm, Shunqiang Li, Gerburg M. Wulf, Olmo Sonzogni, Chen Huang, Suhas Vasaikar, Susan G. Hilsenbeck, Bing Zhang, Aleksandar Milosavljevic, Michael T. Lewis
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105799- (2023)
Summary: Although systemic chemotherapy remains the standard of care for TNBC, even combination chemotherapy is often ineffective. The identification of biomarkers for differential chemotherapy response would allow for the selection of responsive pat
Externí odkaz:
https://doaj.org/article/2b0f86504c374089a6c4e5c09a09e1cb
Publikováno v:
Education Sciences, Vol 13, Iss 5, p 442 (2023)
High-quality principal internships are defined, in part, by support from high-quality principal mentors. We traced the development and quality of principal mentor–intern relationships during an academic school year and found that mentors played a s
Externí odkaz:
https://doaj.org/article/6e5b112e46a84c1386d3c49c59a3e79c
Autor:
Lacey E. Hankin, Chad T. Anderson
Publikováno v:
Forests, Vol 13, Iss 9, p 1512 (2022)
Understanding the patterns and underlying drivers of forest structure is critical for managing landscape processes and multiple resource management. Merging several landscape-scale datasets, including long-term fire histories, airborne LiDAR, and dow
Externí odkaz:
https://doaj.org/article/838b508f999047b885633f730fc1a5af