Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lacey B. Sell"'
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102852- (2024)
Summary: Many motor and neurodegenerative diseases affect the peripheral nervous system (PNS). The myelinated axons in the sciatic nerves offer valuable insights into the pathology of these diseases. Here, we present a protocol for isolating and proc
Externí odkaz:
https://doaj.org/article/974c146b90d3451ea803985ebeeaf7f0
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113274- (2023)
Summary: The Contactin-associated protein 1 (Cntnap1) mouse mutants fail to establish proper axonal domains in myelinated axons. Human CNTNAP1 mutations are linked to hypomyelinating neuropathy-3, which causes severe neurological deficits. To underst
Externí odkaz:
https://doaj.org/article/916ab549533a4fbf80001fac1188b6ef
Autor:
William Jerome Doyle, Lacey B. Sell, Christina C. Ramelow, Hannah M. Kohl, Kristina R. Hoffman, Jasleen K. Bains, Kevin D. Strawn, Theresa Hervin, Trevor O. Kirby, K Michael Gibson, Jean-Babtiste Roullet, Javier Ochoa-Repárez
Publikováno v:
The Journal of Immunology. 208:105.11-105.11
Multiple Sclerosis (MS) is an autoimmune disease that causes T-cells to attack and degrade the myelin sheath of neurons in the spinal cord and brain. Farnesol is synthesized by plants and mammals and has anti-inflammatory along with neuroprotective a
Autor:
Jasleen K. Bains, Lacey B. Sell, Trevor O. Kirby, William J. Doyle, Hannah M. Kohl, Jean-Baptiste Roullet, Kevin D. Strawn, Javier Ochoa-Repáraz, K. Michael Gibson, Christina C. Ramelow, Theresa Hevrin, Kristina Hoffman
Publikováno v:
Clin Immunol
Farnesol is a 15‑carbon organic isoprenol synthesized by plants and mammals with anti-oxidant, anti-inflammatory, and neuroprotective activities. We sought to determine whether farnesol treatment would result in protection against murine experiment
Autor:
Lacey B. Sell, Javier Ochoa-Repáraz
Publikováno v:
Emerging Drugs and Targets for Multiple Sclerosis ISBN: 9781788014502
The gut microbiome aids in immune, endocrine and neural system functions and development. A disruption in the homeostasis of normal intestinal microbiota, known as dysbiosis, can result in changes believed to lead to pathological pathways which may m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ac47dd94535d172a609d1ef4f8cf1a
https://doi.org/10.1039/9781788016070-00302
https://doi.org/10.1039/9781788016070-00302
Autor:
Lacey B Sell, Christina C. Ramelow, Kevin D. Strawn, Theresa Hevrin, Trevor O. Kirby, K. Michael Gibson, Jean-Baptiste Roullet, Javier Ochoa-Repáraz
Publikováno v:
The Journal of Immunology. 204:219.7-219.7
Many advancements in the understanding of multiple sclerosis (MS) have been made through the use of laboratory models. One commonly used model is experimental autoimmune encephalomyelitis (EAE), a mouse model characterized by central nervous system (
Autor:
Christina C Ramelow, Lacey B. Sell, Kevin D. Strawn, Theresa Hevrin, Trevor O. Kirby, K. Michael Gibson, Jean-Baptiste Roullet, Javier Ochoa-Repáraz
Publikováno v:
The Journal of Immunology. 204:160.14-160.14
Farnesol (FOL) is a naturally-produced 15-carbon organic acyclic sesquiterpene alcohol (isoprenol) that acts as a potent blocker of neuronal voltage-gated Ca2+ channels (L- and N-type) and is found in the human brain. FOL has potent anti-oxidant and