Binding Mechanism between Acetylcholinesterase and Drugs Pazopanib and Lapatinib: Biochemical and Biophysical Studies.

Autor: Meira Menezes T; Fundamental Chemistry Department, Federal University of Pernambuco, Recife 50670-901, Brazil., Assis C; Department of Biochemistry and Physiology, Federal University of Pernambuco, Recife 50670-901, Brazil., Lacerda Cintra AJ; Department of Biochemistry and Physiology, Federal University of Pernambuco, Recife 50670-901, Brazil., Silva Dos Santos RC; Department of Education, Rural Federal University of Pernambuco, Recife 52171-900, Brazil., Martins do Vale WK; Department of Education, Rural Federal University of Pernambuco, Recife 52171-900, Brazil., Max Gomes Martins R; Post-Graduate in Biotechnology Multi-Institutional Program, PPGBIOTEC, Federal University of Amazonas, Manaus 69067-005, Brazil., de Souza Bezerra R; Department of Biochemistry and Physiology, Federal University of Pernambuco, Recife 50670-901, Brazil., Seabra GM; Department of Medicinal Chemistry, University of Florida, Gainesville, Florida 32610, United States., Li C; Department of Medicinal Chemistry, University of Florida, Gainesville, Florida 32610, United States., Neves JL; Fundamental Chemistry Department, Federal University of Pernambuco, Recife 50670-901, Brazil.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Dec 15; Vol. 12 (24), pp. 4500-4511. Date of Electronic Publication: 2021 Nov 22.