Phase IIa, randomised, double-blind study of GSK3389404 in patients with chronic hepatitis B on stable nucleos(t)ide therapy.

Autor: Yuen MF; Department of Medicine and State Key Laboratory of Liver Research, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. Electronic address: mfyuen@hku.hk., Heo J; Department of Internal Medicine, College of Medicine, Pusan National University, and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea., Kumada H; Department of Hepatology, Toranomon Hospital Kajigaya, Kanagawa, Japan., Suzuki F; Department of Hepatology, Toranomon Hospital Kajigaya, Kanagawa, Japan., Suzuki Y; Department of Hepatology, Toranomon Hospital, Tokyo, Japan., Xie Q; Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Jia J; Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China., Karino Y; Department of Hepatology, Hokkaido P.W.F.a.C. Sapporo-Kosei General Hospital, Hokkaido, Japan., Hou J; Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China., Chayama K; Collaborative Research Laboratory of Medical Innovation, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Imamura M; Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Lao-Tan JY; Gastroenterology, Cebu Doctors University Hospital, Cebu, Philippines., Lim SG; Division of Gastroenterology & Hepatology, Department of Medicine, National University Health System, Singapore., Tanaka Y; Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Xie W; Center of Liver Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China., Yoon JH; Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea., Duan Z; Artifical Liver Center, Beijing Youan Hospital, Capital Medical University, Beijing, China., Kurosaki M; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan., Park SJ; Department of Gastroenterology and Hepatology, Inje University Busan Paik Hospital, Busan, Republic of Korea., Labio ME; Section of Gastroenterology and Hepatology, Department of Medicine, Makati Medical Center, Makati, Philippines., Kumar R; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore., Kweon YO; Division of Gastroenterology and Hepatology, Kyungpook National University Hospital, Daegu, Republic of Korea., Yim HJ; Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea., Tao Y; R&D Projects Clinical Platforms and Sciences, GSK, Collegeville, PA, USA., Cremer J; Hepatology GI Clinical Sciences, GSK, NC, USA., Elston R; Hepatology GI Clinical Sciences, GSK, Hertfordshire, UK., Davies M; Global Safety, GSK, Brentford, UK., Baptiste-Brown S; R&D Global Medical Affairs, GSK, PA, USA., Han K; Clinical Pharmacology Modeling & Simulation, GSK, PA, USA., Campbell FM; Hepatology GI Clinical Sciences, GSK, Hertfordshire, UK., Paff M; Medicine Development Leaders, GSK, PA, USA., Theodore D; Hepatology GI Clinical Sciences, GSK, NC, USA.

Publikováno v: Journal of hepatology [J Hepatol] 2022 Oct; Vol. 77 (4), pp. 967-977. Date of Electronic Publication: 2022 Jun 15.