Simultaneous MEKC-DAD and smart spectrophotometric assays of thiocolchicoside and etoricoxib in challenging concentration ratio mixtures

Autor: Kamal Miranda F., Elonsy Sohila M., Labib Hala F., Younis Sameh E.

Publikováno v: Reviews in Analytical Chemistry, Vol 41, Iss 1, Pp 137-145 (2022)

Potent muscle relaxant (thiocolchicoside, TCC) and nonsteroidal anti-inflammatory drug (etoricoxib, ETXB) fixed-dose combination is formulated at relatively high 1:15 and 1:7.5 ratios for TCC and ETXB, respectively. Since the minor component (TCC) ha

Externí odkaz: https://doaj.org/article/8935cf1025924bc98ad98f898e099ac9

Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones

Autor: Elzahhar, Perihan A., Alaaeddine, Rana, Ibrahim, Tamer M., Nassra, Rasha, Ismail, Azza, Chua, Benjamin S.K., Frkic, Rebecca L., Bruning, John B., Wallner, Nadja, Knape, Tilo, von Knethen, Andreas, Labib, Hala, El-Yazbi, Ahmed F., Belal, Ahmed S.F.

Publikováno v: In European Journal of Medicinal Chemistry 1 April 2019 167:562-582

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Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones.

Autor: Elzahhar PA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Alaaeddine RA; Department of Pharmacology and Toxicology, Faculty of Medicine and Medical Centre, American University of Beirut, Beirut, Lebanon., Nassra R; Department of Medical Biochemistry, Faculty of Medicine, Alexandria University, Alexandria, Egypt., Ismail A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Labib HF; Department of Pharmaceutical Chemistry, College of Pharmacy, Arab Academy of Science Technology and Maritime Transport, Alexandria, Egypt., Temraz MG; Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Belal ASF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., El-Yazbi AF; Department of Pharmacology and Toxicology, Faculty of Medicine and Medical Centre, American University of Beirut, Beirut, Lebanon.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, E gypt.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 669-684.