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The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance.

Autor: Sanese, Paola, De Marco, Katia, Lepore Signorile, Martina, La Rocca, Francesca, Forte, Giovanna, Latrofa, Marialaura, Fasano, Candida, Disciglio, Vittoria, Di Nicola, Elisabetta, Pantaleo, Antonino, Bianco, Giusy, Spilotro, Vito, Ferroni, Claudia, Tubertini, Matilde, Labarile, Nicoletta, De Marinis, Lucia, Armentano, Raffaele, Gigante, Gianluigi, Lantone, Valerio, Lantone, Giuliano

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966); 5/30/2024, Vol. 43, p1-23, 23p

Downregulation of γ-Catenin by miR-195-5p Inhibits Colon Cancer Progression, Regulating Desmosome Function.

Autor: Piccinno E; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy., Scalavino V; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy., Labarile N; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy., Bianco G; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy., Savino MT; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy., Armentano R; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy., Giannelli G; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy., Serino G; National Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 29; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 29.