Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Laasya, Samhita"'
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008654 (2020)
Mistranslation is typically deleterious for cells, although specific mistranslated proteins can confer a short-term benefit in a particular environment. However, given its large overall cost, the prevalence of high global mistranslation rates remains
Externí odkaz:
https://doaj.org/article/06118c46c19f4cc7b5dca9e188778c60
Autor:
Laasya Samhita
Publikováno v:
Journal of biosciences. 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c86780ce92bd5aeaee594f68180dbd
https://pubmed.ncbi.nlm.nih.gov/36222163
https://pubmed.ncbi.nlm.nih.gov/36222163
Autor:
Laasya Samhita
The notion that there is a one to one mapping from genotype to phenotype was overturned a long time ago. Along with genotype and environment, ‘non-genetic changes’ orchestrated by altered RNA and protein molecules also guide the development of ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3a0100baa48b8078bee7615cdb698b
Publikováno v:
Journal of bacteriology. 201(15)
Occasionally, ribosomes stall on mRNAs prior to the completion of the polypeptide chain. In Escherichia coli and other eubacteria, tmRNA-mediated trans-translation is a major mechanism that recycles the stalled ribosomes. The tmRNA possesses a tRNA-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b109577155d7bdc8ad4d03c79c41036
https://pubmed.ncbi.nlm.nih.gov/21602351
https://pubmed.ncbi.nlm.nih.gov/21602351
Mistranslation is typically deleterious, but can sometimes be beneficial. Although a specific mistranslated protein can confer a short-term benefit in a particular environment, the prevalence of high global mistranslation rates remains puzzling given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a61320c85dc9a3fcaf640999b847b28
Publikováno v:
Journal of Bacteriology. 195:4202-4209
In all domains of life, initiator tRNA functions exclusively at the first step of protein synthesis while elongator tRNAs extend the polypeptide chain. Unique features of initiator tRNA enable it to preferentially bind the ribosomal P site and initia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ac521c51890a9d895790c88961a93b
https://doi.org/10.1128/jb.00637-13
https://doi.org/10.1128/jb.00637-13
Autor:
Umesh Varshney, Laasya Samhita
Publikováno v:
Resonance. 15:526-537
The 2009 Nobel Prize in Chemistry was awarded jointly to Venkatraman Ramakrishnan, Thomas Steitz and Ada Yonath “for studies on the structure and function of the ribosome”. The ribosome is a massive molecular machine comprising proteins and RNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddacce939fe15760629a924c92f5687
https://doi.org/10.1007/s12045-010-0059-8
https://doi.org/10.1007/s12045-010-0059-8
Autor:
Laasya Samhita
Publikováno v:
Resonance. 15:434-440
The Handicap Principle is an idea proposed by the husband and wife scientist team of Amotz and Avishag Zahavi from Israel in the 1970’s. It is among the most innovative ideas of the 20th century in the field of behavioural biology and attempts to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6afcdb0690a1e5b554ef2c57ffac3e8c
https://doi.org/10.1007/s12045-010-0070-0
https://doi.org/10.1007/s12045-010-0070-0
Publikováno v:
Tuberculosis. 89:453-464
The translation elongation factor G (EFG) is encoded by the fusA gene. Several bacteria possess a second fusA-like locus, fusA2 which encodes EFG2. A comparison of EFG and EFG2 from various bacteria reveals that EFG2 preserves domain organization and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e934a5989c4afb740a7c3007089815
https://doi.org/10.1016/j.tube.2009.06.003
https://doi.org/10.1016/j.tube.2009.06.003
Publikováno v:
IndraStra Global.
Multiple copies of a gene require enhanced investment on the part of the cell and, as such, call for an explanation. The observation that Escherichia coli has four copies of initiator tRNA (tRNA i ) genes, encoding a special tRNA (tRNA fMet ) require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea2c6afab74bbddb1b208bca9d67a0c
https://igi.indrastra.com/items/show/190126
https://igi.indrastra.com/items/show/190126