Mitochondrial Pyruvate Carrier Inhibition Attenuates Hepatic Stellate Cell Activation and Liver Injury in a Mouse Model of Metabolic Dysfunction-associated Steatotic Liver Disease.

Autor: Habibi M; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis., Ferguson D; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis., Eichler SJ; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis., Chan MM; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis., LaPoint A; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis., Shew TM; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis., He M; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis., Lutkewitte AJ; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis., Schilling JD; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis., Cho KY; Department of Chemistry, Siteman Cancer Center, Center for Metabolomics and Isotope Tracing, Washington University in St. Louis, MO 63110 USA., Patti GJ; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis.; Department of Chemistry, Siteman Cancer Center, Center for Metabolomics and Isotope Tracing, Washington University in St. Louis, MO 63110 USA., Finck BN; Department of Medicine, Center for Human Nutrition, Washington University in St. Louis.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 25. Date of Electronic Publication: 2023 Aug 25.