Zobrazeno 1 - 10
of 19
pro vyhledávání: '"LaNisha L Patterson"'
Autor:
Caitlan D Byerly, Shubhajit Mitra, LaNisha L Patterson, Nicholas A Pittner, Thangam S Velayutham, Slobodan Paessler, Veljko Veljkovic, Jere W McBride
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010345 (2022)
Ehrlichia chaffeensis (E. chaffeensis) has evolved eukaryotic ligand mimicry to repurpose multiple cellular signaling pathways for immune evasion. In this investigation, we demonstrate that TRP120 has a novel repetitive short linear motif (SLiM) that
Externí odkaz:
https://doaj.org/article/1533b26f8df74cd8bbd6ab17293179a9
Autor:
Jennifer Y Wang, Bing Zhu, LaNisha L Patterson, Madison R Rogan, Clayton E Kibler, Jere W McBride
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008541 (2020)
Ehrlichia chaffeensis (E. chaffeensis) exploits evolutionarily conserved Notch and Wnt host cell signaling pathways to downregulate innate immune host defenses and promote infection. The multifunctional E. chaffeensis TRP120 effector which has HECT E
Externí odkaz:
https://doaj.org/article/024642615fcb48e69c5f39f4214d8aa7
Autor:
Caitlan D. Byerly, Bing Zhu, Paityn A. Warwick, LaNisha L. Patterson, Nicholas A. Pittner, Jere W. McBride
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Ehrlichia chaffeensis: TRP120 is a multifunctional effector that acts as a ligand mimic to activate evolutionary conserved eukaryotic signaling pathways Notch, Wnt, Hedgehog and Hippo. In addition, TRP120 is also a HECT E3 ubiquitin ligase known to u
Externí odkaz:
https://doaj.org/article/74e86eb21971455da14b4ac9d6eb7ece
Autor:
Caitlan D. Byerly, LaNisha L. Patterson, Nicholas A. Pittner, Regina N. Solomon, Jignesh G. Patel, Madison R. Rogan, Jere W. McBride
Publikováno v:
bioRxiv
Ehrlichia chaffeensisTRP120 effector has evolved short linear motif (SLiM) ligand mimicry to repurpose multiple evolutionarily conserved cellular signaling pathways including Wnt, Notch and Hedgehog. In this investigation, we demonstrate thatE. chaff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911851649555262b3cce4d36393e01d5
https://europepmc.org/articles/PMC10028901/
https://europepmc.org/articles/PMC10028901/
Autor:
LaNisha L. Patterson, Caitlan D. Byerly, Regina Solomon, Nicholas Pittner, Duc Cuong Bui, Jignesh Patel, Jere W. McBride
Publikováno v:
bioRxiv
Ehrlichia chaffeensishas evolved multiple strategies to evade innate defenses of the mononuclear phagocyte. Recently, we reported theE. chaffeensisTRP120 effector functions as a Notch ligand mimetic and a ubiquitin ligase that degrades the nuclear tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bcaf41891942da607e7e5a6fc25ec6
https://doi.org/10.1101/2023.01.06.523066
https://doi.org/10.1101/2023.01.06.523066
Autor:
LaNisha L. Patterson, Thangam Sudha Velayutham, Caitlan D. Byerly, Duc Cuong Bui, Jignesh Patel, Veljko Veljkovic, Slobodan Paessler, Jere W. McBride
Publikováno v:
mBio. 13
Ehrlichia chaffeensis evades innate host defenses by reprogramming the mononuclear phagocyte through mechanisms that involve exploitation of multiple evolutionarily conserved cellular signaling pathways including Notch. This immune evasion strategy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8110bdcc70bb98349aaf9583bc1f4d7f
https://doi.org/10.1128/mbio.00076-22
https://doi.org/10.1128/mbio.00076-22
Autor:
Sankaranarayan Kannan, Mary E. Irwin, Shelley M. Herbrich, Tiewei Cheng, LaNisha L. Patterson, Marisa J. L. Aitken, Kapil Bhalla, M. James You, Marina Konopleva, Patrick A. Zweidler-McKay, Joya Chandra
Publikováno v:
Antioxidants; Volume 11; Issue 4; Pages: 717
Acute myeloid leukemia (AML) is a molecularly heterogenous hematological malignancy, with one of the most common mutations being internal tandem duplication (ITD) of the juxtamembrane domain of the fms-like tyrosine kinase receptor-3 (FLT3). Despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30a6cc113e26b693bea934c1014e7e3
https://pubmed.ncbi.nlm.nih.gov/35453402
https://pubmed.ncbi.nlm.nih.gov/35453402
Autor:
Tian Luo, Caitlan D. Byerly, Madison R. Rogan, Slobodan Paessler, Veljko Veljkovic, Jere W. McBride, Bethany R. Quade, LaNisha L. Patterson
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
mSphere
mSphere
Ehrlichia chaffeensis expresses the TRP120 multifunctional effector, which is known to play a role in phagocytic entry, on the surface of infectious dense-cored ehrlichiae, but a cognate host receptor has not been identified. We recently reported tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed368c522fe6adbbf51b4cb283945300
https://doi.org/10.1128/msphere.00216-21
https://doi.org/10.1128/msphere.00216-21
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Autophagy is a vital conserved degradative process that maintains cellular homeostasis by recycling or eliminating dysfunctional cellular organelles and proteins. More recently, autophagy has become a well-recognized host defense mechanism against in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3404beee0740c01106665f5b2165d866
https://www.frontiersin.org/articles/10.3389/fimmu.2021.642771/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.642771/full
Autor:
LaNisha L. Patterson, Clayton E. Kibler, Jennifer Y. Wang, Madison R. Rogan, Jere W. McBride, Bing Zhu
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008541 (2020)
PLoS Pathogens
PLoS Pathogens
Ehrlichia chaffeensis (E. chaffeensis) exploits evolutionarily conserved Notch and Wnt host cell signaling pathways to downregulate innate immune host defenses and promote infection. The multifunctional E. chaffeensis TRP120 effector which has HECT E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3064923be5c1134652490c3dbcd4cb
https://doaj.org/article/024642615fcb48e69c5f39f4214d8aa7
https://doaj.org/article/024642615fcb48e69c5f39f4214d8aa7