Zobrazeno 1 - 10
of 138
pro vyhledávání: '"LaDeana W Hillier"'
Autor:
Reuben M Buckley, Brian W Davis, Wesley A Brashear, Fabiana H G Farias, Kei Kuroki, Tina Graves, LaDeana W Hillier, Milinn Kremitzki, Gang Li, Rondo P Middleton, Patrick Minx, Chad Tomlinson, Leslie A Lyons, William J Murphy, Wesley C Warren
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1008926 (2020)
The domestic cat (Felis catus) numbers over 94 million in the USA alone, occupies households as a companion animal, and, like humans, suffers from cancer and common and rare diseases. However, genome-wide sequence variant information is limited for t
Externí odkaz:
https://doaj.org/article/f66873bec5b54e57a16b45a9e350d059
Autor:
W Clay Spencer, Rebecca McWhirter, Tyne Miller, Pnina Strasbourger, Owen Thompson, LaDeana W Hillier, Robert H Waterston, David M Miller
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112102 (2014)
The simple and well-described structure of the C. elegans nervous system offers an unprecedented opportunity to identify the genetic programs that define the connectivity and function of individual neurons and their circuits. A correspondingly precis
Externí odkaz:
https://doaj.org/article/33da9be713da4733ac6ab9fe7555e361
Autor:
Ilka Engelmann, Aurélien Griffon, Laurent Tichit, Frédéric Montañana-Sanchis, Guilin Wang, Valerie Reinke, Robert H Waterston, LaDeana W Hillier, Jonathan J Ewbank
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19055 (2011)
While Caenorhabditis elegans specifically responds to infection by the up-regulation of certain genes, distinct pathogens trigger the expression of a common set of genes. We applied new methods to conduct a comprehensive and comparative study of the
Externí odkaz:
https://doaj.org/article/c4bab35170d0412eaed3e10815406f23
Autor:
Mei Zhong, Wei Niu, Zhi John Lu, Mihail Sarov, John I Murray, Judith Janette, Debasish Raha, Karyn L Sheaffer, Hugo Y K Lam, Elicia Preston, Cindie Slightham, LaDeana W Hillier, Trisha Brock, Ashish Agarwal, Raymond Auerbach, Anthony A Hyman, Mark Gerstein, Susan E Mango, Stuart K Kim, Robert H Waterston, Valerie Reinke, Michael Snyder
Publikováno v:
PLoS Genetics, Vol 6, Iss 2, p e1000848 (2010)
Transcription factors are key components of regulatory networks that control development, as well as the response to environmental stimuli. We have established an experimental pipeline in Caenorhabditis elegans that permits global identification of t
Externí odkaz:
https://doaj.org/article/3935b829c33d42ab895b0ebada48e8f7
Autor:
Deanna M Church, Leo Goodstadt, Ladeana W Hillier, Michael C Zody, Steve Goldstein, Xinwe She, Carol J Bult, Richa Agarwala, Joshua L Cherry, Michael DiCuccio, Wratko Hlavina, Yuri Kapustin, Peter Meric, Donna Maglott, Zoë Birtle, Ana C Marques, Tina Graves, Shiguo Zhou, Brian Teague, Konstantinos Potamousis, Christopher Churas, Michael Place, Jill Herschleb, Ron Runnheim, Daniel Forrest, James Amos-Landgraf, David C Schwartz, Ze Cheng, Kerstin Lindblad-Toh, Evan E Eichler, Chris P Ponting, Mouse Genome Sequencing Consortium
Publikováno v:
PLoS Biology, Vol 7, Iss 5, p e1000112 (2009)
The mouse (Mus musculus) is the premier animal model for understanding human disease and development. Here we show that a comprehensive understanding of mouse biology is only possible with the availability of a finished, high-quality genome assembly.
Externí odkaz:
https://doaj.org/article/a202294c2cc6477980c4641703f4b0a7
Autor:
David J Begun, Alisha K Holloway, Kristian Stevens, Ladeana W Hillier, Yu-Ping Poh, Matthew W Hahn, Phillip M Nista, Corbin D Jones, Andrew D Kern, Colin N Dewey, Lior Pachter, Eugene Myers, Charles H Langley
Publikováno v:
PLoS Biology, Vol 5, Iss 11, p e310 (2007)
The population genetic perspective is that the processes shaping genomic variation can be revealed only through simultaneous investigation of sequence polymorphism and divergence within and between closely related species. Here we present a populatio
Externí odkaz:
https://doaj.org/article/6b804cd42a204968b1a74d54a4da1c4d
Autor:
LaDeana W Hillier, Raymond D Miller, Scott E Baird, Asif Chinwalla, Lucinda A Fulton, Daniel C Koboldt, Robert H Waterston
Publikováno v:
PLoS Biology, Vol 5, Iss 7, p e167 (2007)
To determine whether the distinctive features of Caenorhabditis elegans chromosomal organization are shared with the C. briggsae genome, we constructed a single nucleotide polymorphism-based genetic map to order and orient the whole genome shotgun as
Externí odkaz:
https://doaj.org/article/4a9fc8e6c0b94e84b49bd469afed13f4
Autor:
José M Ranz, Damien Maurin, Yuk S Chan, Marcin von Grotthuss, LaDeana W Hillier, John Roote, Michael Ashburner, Casey M Bergman
Publikováno v:
PLoS Biology, Vol 5, Iss 6, p e152 (2007)
That closely related species often differ by chromosomal inversions was discovered by Sturtevant and Plunkett in 1926. Our knowledge of how these inversions originate is still very limited, although a prevailing view is that they are facilitated by e
Externí odkaz:
https://doaj.org/article/e66ca74ac0ca4024b48d8b760c7659d8
Autor:
Lincoln D Stein, Zhirong Bao, Darin Blasiar, Thomas Blumenthal, Michael R Brent, Nansheng Chen, Asif Chinwalla, Laura Clarke, Chris Clee, Avril Coghlan, Alan Coulson, Peter D'Eustachio, David H A Fitch, Lucinda A Fulton, Robert E Fulton, Sam Griffiths-Jones, Todd W Harris, LaDeana W Hillier, Ravi Kamath, Patricia E Kuwabara, Elaine R Mardis, Marco A Marra, Tracie L Miner, Patrick Minx, James C Mullikin, Robert W Plumb, Jane Rogers, Jacqueline E Schein, Marc Sohrmann, John Spieth, Jason E Stajich, C Wei, David Willey, Richard K Wilson, Richard Durbin, Robert H Waterston
Publikováno v:
PLoS Biology, Vol 1, Iss 2, p E45 (2003)
The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a common ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. They have the same chromosome number and genome sizes, and they occupy th
Externí odkaz:
https://doaj.org/article/103ed0f984d9479e8740763c1a2676dc
Autor:
Melanie Sorensen, Yafei Mao, Sofie R. Salama, Claudia Rita Catacchio, Andy Wing Chun Pang, Françoise Thibaud-Nissen, Carl Baker, LaDeana W. Hillier, Ruiyang Li, Arvis Sulovari, Philip C. Dishuck, PingHsun Hsieh, Katherine M. Munson, Ludovica Mercuri, Jason D Fernandes, Jessica M. Storer, Joyce V. Lee, Benedict Paten, Mark A. Batzer, Peter A. Audano, David Porubsky, Tzu-Hsueh Huang, Jason G. Underwood, Evan E. Eichler, Jinna Hoffman, William T. Harvey, Kendra Hoekzema, Jerilyn A. Walker, Ian T. Fiddes, David Gordon, Marina Haukness, Alex Hastie, Alexandra P. Lewis, Francesca Antonacci, Mario Ventura, Shwetha C. Murali, Francesco Montinaro, Ilaria Piccolo, Mark Diekhans
Publikováno v:
Nature
The divergence of chimpanzee and bonobo provides one of the few examples of recent hominid speciation1,2. Here we describe a fully annotated, high-quality bonobo genome assembly, which was constructed without guidance from reference genomes by applyi