p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

Autor: Svensson K; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA., LaBarge SA; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA., Sathe A; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA., Martins VF; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA.; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, CA, USA., Tahvilian S; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA., Cunliffe JM; Department of Biochemistry and Molecular Biology, School of Medicine, Oregon Health and Science University, Portland, OR, USA., Sasik R; Center for Computational Biology and Bioinformatics, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Mahata SK; VA San Diego Healthcare System, San Diego, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA., Meyer GA; Program in Physical Therapy and Departments of Neurology, Biomedical Engineering and Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO, USA., Philp A; Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia., David LL; Department of Biochemistry and Molecular Biology, School of Medicine, Oregon Health and Science University, Portland, OR, USA., Ward SR; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA.; Department of Radiology, University of California San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA., McCurdy CE; Department of Human Physiology, University of Oregon, Eugene, OR, USA., Aslan JE; Department of Biochemistry and Molecular Biology, School of Medicine, Oregon Health and Science University, Portland, OR, USA.; Knight Cardiovascular Institute, School of Medicine, Oregon Health and Science University, Portland, OR, USA.; Department of Biomedical Engineering, School of Medicine, Oregon Health and Science University, Portland, OR, USA., Schenk S; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA.; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, CA, USA.

Publikováno v: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2020 Apr; Vol. 11 (2), pp. 464-477. Date of Electronic Publication: 2020 Jan 03.

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

Autor: Martins VF; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California.; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, California., Dent JR; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California., Svensson K; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California., Tahvilian S; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California., Begur M; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California., Lakkaraju S; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California., Buckner EH; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California., LaBarge SA; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California., Hetrick B; Department of Human Physiology, University of Oregon , Eugene, Oregon., McCurdy CE; Department of Human Physiology, University of Oregon , Eugene, Oregon., Schenk S; Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, California.; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, California.

Publikováno v: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2019 Jun 01; Vol. 316 (6), pp. E1024-E1035. Date of Electronic Publication: 2019 Mar 19.

Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation.

Autor: Dent JR; School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, UK., Martins VF; Department of Orthopaedic Surgery, University of California, La Jolla, San Diego, CA, USA; Biomedical Sciences Graduate Program, University of California, La Jolla, San Diego, CA, USA., Svensson K; Department of Orthopaedic Surgery, University of California, La Jolla, San Diego, CA, USA., LaBarge SA; Department of Orthopaedic Surgery, University of California, La Jolla, San Diego, CA, USA., Schlenk NC; Department of Orthopaedic Surgery, University of California, La Jolla, San Diego, CA, USA., Esparza MC; Department of Orthopaedic Surgery, University of California, La Jolla, San Diego, CA, USA., Buckner EH; Department of Orthopaedic Surgery, University of California, La Jolla, San Diego, CA, USA., Meyer GA; Program in Physical Therapy, Washington University School of Medicine, St Louis, MO, USA., Hamilton DL; School of Sport, Stirling University, Stirling, UK., Schenk S; Department of Orthopaedic Surgery, University of California, La Jolla, San Diego, CA, USA; Biomedical Sciences Graduate Program, University of California, La Jolla, San Diego, CA, USA. Electronic address: sschenk@ucsd.edu., Philp A; School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, UK. Electronic address: a.philp@bham.ac.uk.

Publikováno v: Molecular metabolism [Mol Metab] 2017 Dec; Vol. 6 (12), pp. 1574-1584. Date of Electronic Publication: 2017 Oct 16.

p300 is not required for metabolic adaptation to endurance exercise training.

Autor: LaBarge SA; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Migdal CW; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Buckner EH; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Okuno H; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Gertsman I; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Stocks B; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Barshop BA; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Nalbandian SR; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Philp A; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., McCurdy CE; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA., Schenk S; Department of Orthopaedic Surgery and Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA; School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Edgbaston, United Kingdom; and Department of Human Physiology, University of Oregon, Eugene, Oregon, USA sschenk@ucsd.edu.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2016 Apr; Vol. 30 (4), pp. 1623-33. Date of Electronic Publication: 2015 Dec 28.