Selective activation of Gαob by an adenosine A 1 receptor agonist elicits analgesia without cardiorespiratory depression.

Autor: Wall MJ; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK. mark.wall@warwick.ac.uk., Hill E; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Huckstepp R; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Barkan K; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK., Deganutti G; Centre for Sport, Exercise and Life Sciences (CSELS), Faculty of Health and Life Sciences, Coventry University, Coventry, CV1 2DS, UK.; School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, UK., Leuenberger M; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012, Bern, Switzerland., Preti B; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012, Bern, Switzerland., Winfield I; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK., Carvalho S; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK., Suchankova A; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK., Wei H; NeuroSolutions Ltd, Coventry, UK., Safitri D; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK.; Pharmacology and Clinical Pharmacy Research Group, School of Pharmacy, Bandung Institute of Technology, Bandung, 40132, Indonesia., Huang X; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK., Imlach W; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Innovation Walk, Clayton, VIC, 3800, Australia., La Mache C; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Dean E; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Hume C; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Hayward S; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Oliver J; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Zhao FY; NeuroSolutions Ltd, Coventry, UK., Spanswick D; NeuroSolutions Ltd, Coventry, UK.; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Innovation Walk, Clayton, VIC, 3800, Australia.; Warwick Medical School, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK., Reynolds CA; Centre for Sport, Exercise and Life Sciences (CSELS), Faculty of Health and Life Sciences, Coventry University, Coventry, CV1 2DS, UK.; School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, UK., Lochner M; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012, Bern, Switzerland., Ladds G; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK. grl30@cam.ac.uk., Frenguelli BG; School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry, CV4 7AL, UK. b.g.frenguelli@warwick.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2022 Jul 18; Vol. 13 (1), pp. 4150. Date of Electronic Publication: 2022 Jul 18.

TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review.

Autor: Alizadehasl, Azin^1,2, Alavi, Maryam Sadat², Alavi, Mohaddeseh Sadat³, Roohbakhsh, Ali^4,5 roohbakhsha@mums.ac.ir

Publikováno v: Iranian Journal of Basic Medical Sciences. Mar2024, Vol. 27 Issue 3, p270-278. 9p.

Progress on the development of Class A GPCR-biased ligands.

Autor: Morales P; Instituto de Química Médica, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Scharf MM; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Bermudez M; Institute for Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany., Egyed A; Medicinal Chemistry Research Group and National Drug Discovery and Development Laboratory, Research Centre for Natural Sciences, Budapest, Hungary., Franco R; Molecular Neurobiology Laboratory, Department of Biochemistry and Molecular Biology, Universitat de Barcelona, Barcelona, Spain.; CiberNed. Network Center for Neurodegenerative Diseases, National Spanish Health Institute Carlos III, Madrid, Spain.; School of Chemistry, Universitat de Barcelona, Barcelona, Spain., Hansen OK; Laboratory of Molecular Pharmacology, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jagerovic N; Instituto de Química Médica, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Jakubík J; Institute of Physiology Czech Academy of Sciences, Prague, Czech Republic., Keserű GM; Medicinal Chemistry Research Group and National Drug Discovery and Development Laboratory, Research Centre for Natural Sciences, Budapest, Hungary., Kiss DJ; Medicinal Chemistry Research Group and National Drug Discovery and Development Laboratory, Research Centre for Natural Sciences, Budapest, Hungary., Kozielewicz P; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Larsen O; Laboratory of Molecular Pharmacology, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Majellaro M; Celtarys Research S.L., Santiago de Compostela, Spain., Mallo-Abreu A; Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela, Santiago de Compostela, Spain.; Laboratory of Medicinal Chemistry (CSIC Associated Unit), Faculty of Pharmacy and Food Sciences, Universitat de Barcelona, Barcelona, Spain.; Institute of Biomedicine (IBUB), Universitat de Barcelona, Barcelona, Spain., Navarro G; CiberNed. Network Center for Neurodegenerative Diseases, National Spanish Health Institute Carlos III, Madrid, Spain.; Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, Universitat de Barcelona, Barcelona, Spain., Prieto-Díaz R; Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela, Santiago de Compostela, Spain., Rosenkilde MM; Laboratory of Molecular Pharmacology, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sotelo E; Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela, Santiago de Compostela, Spain., Stark H; Heinrich Heine University Düsseldorf, Institut fuer Pharmazeutische und Medizinische Chemie, Duesseldorf, Germany., Werner T; Heinrich Heine University Düsseldorf, Institut fuer Pharmazeutische und Medizinische Chemie, Duesseldorf, Germany., Wingler LM; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Sep 11. Date of Electronic Publication: 2024 Sep 11.

Transient receptor potential Ankyrin‐1 (TRPA1) agonists suppress myelination and induce demyelination in organotypic cortical slices.

Autor: Giacco, Vincenzo, Flower, Grace, Artamonova, Maria, Hunter, Jake, Padilla Requerey, Aitana, Hamilton, Nicola B.

Publikováno v: Glia; Jun2023, Vol. 71 Issue 6, p1402-1413, 12p

Les maladies des plantes maraîchères

Autor: Francis Rouxel, Robert Lafon, Dominique Blancard, Charles-Marie Messiaen

Cet ouvrage en impression à la demande sera envoyé sous 3 semaines environ (France métropolitaine) et dans un colis séparé en cas de commande avec un autre livre papier.Cette nouvelle édition des Maladies des plantes maraîchères (dernière é