Zobrazeno 1 - 10
of 62
pro vyhledávání: '"László Őrfi"'
Autor:
Csenge Szász, Domonkos Pap, Beáta Szebeni, Péter Bokrossy, László Őrfi, Attila J. Szabó, Ádám Vannay, Apor Veres-Székely
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17435 (2023)
Tissue fibrosis is characterized by chronic fibroblast activation and consequently excessive accumulation of collagen-rich extracellular matrix. In vitro microplate-based assays are essential to investigate the underlying mechanism and the effect of
Externí odkaz:
https://doaj.org/article/e2b699f041dc490d9d0937fdc22393ac
Autor:
János Garai, Marcell Krekó, László Őrfi, Péter Balázs Jakus, Zoltán Rumbus, Patrik Kéringer, András Garami, Eszter Vámos, Dominika Kovács, Viola Bagóné Vántus, Balázs Radnai, Tamás Lóránd
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1356-1368 (2021)
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine playing crucial role in immunity. MIF exerts a unique tautomerase enzymatic activity that has relevance concerning its multiple functions and its small molecule inhibitors ha
Externí odkaz:
https://doaj.org/article/99c9586e388a44fd96582e44a894d6e8
Autor:
Gábor Bögel, József Murányi, Bálint Szokol, Zoltán Kukor, István Móra, Tamás Kardon, László Őrfi, András Hrabák
Publikováno v:
Heliyon, Vol 8, Iss 1, Pp e08670- (2022)
JAK/STAT pathway plays a well-known role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to identify new signaling pathways and repolarize macrophages by selected protein kinase inhibitors. HL-60
Externí odkaz:
https://doaj.org/article/8d69a1286fd64981bb1ef2a7c567d0de
Autor:
Zoltán-István Szabó, György Orbán, Enikő Borbás, Dóra Csicsák, Szabina Kádár, Béla Fiser, Máté Dobó, Péter Horváth, Eszter Kiss, Lívia Budai, Judit Dobos, Tamás Pálla, László Őrfi, Gergely Völgyi, Gergő Tóth
Publikováno v:
Heliyon, Vol 7, Iss 7, Pp e07581- (2021)
Pomalidomide (POM), a potent anticancer thalidomide analogue was characterized in terms of cyclodextrin complexation to improve its aqueous solubility and maintain its anti-angiogenic activity. The most promising cyclodextrin derivatives were selecte
Externí odkaz:
https://doaj.org/article/1fba1d2d7e7d45489bb62fcd9fd8138f
Autor:
Apor Veres-Székely, Domonkos Pap, Beáta Szebeni, László Őrfi, Csenge Szász, Csenge Pajtók, Eszter Lévai, Attila J. Szabó, Ádám Vannay
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2119 (2022)
Fibroblasts play a central role in diseases associated with excessive deposition of extracellular matrix (ECM), including idiopathic pulmonary fibrosis. Investigation of different properties of fibroblasts, such as migration, proliferation, and colla
Externí odkaz:
https://doaj.org/article/d74f7a658b174325bfa4fce26dde57e6
Autor:
Csilla Temesszentandrási-Ambrus, Szilárd Tóth, Rinkee Verma, Péter Bánhegyi, István Szabadkai, Ferenc Baska, Csaba Szántai-Kis, Ruben C Hartkoorn, Mary A Lingerfelt, Balázs Sarkadi, Gergely Szakács, László Őrfi, Valakunja Nagaraja, Sean Ekins, Ágnes Telbisz
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202749 (2018)
Drug resistant tuberculosis (TB) is a major worldwide health problem. In addition to the bacterial mechanisms, human drug transporters limiting the cellular accumulation and the pharmacological disposition of drugs also influence the efficacy of trea
Externí odkaz:
https://doaj.org/article/1a845305b8a4467da0d15ebe921cc693
Autor:
Vassilis Mavromatidis, Zoltan Varga, Frigyes Waczek, Zoltán Őrfi, László Őrfi, György Kéri, George Mosialos
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95688 (2014)
Epstein-Barr virus (EBV) is a human herpesvirus, which is causally associated with the development of several B lymphocytic malignancies that include Burkitt's lymphomas, Hodgkin's disease, AIDS and posttransplant associated lymphomas. The transformi
Externí odkaz:
https://doaj.org/article/e12914d92de047f4873a5f54d353315e
Autor:
András, Hrabák, Gábor, Bögel, József, Murányi, Viola, Tamási, Krisztina, Németh, Bálint, Szokol, Zoltán, Kukor, Tamás, Kardon, László, Őrfi
Publikováno v:
Molecular Immunology. 153:10-24
The JAK/STAT (Janus Kinase/Signal Transducer and Activator of Transcription) pathway plays a pivotal role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to reveal the relationship of activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e684199e2eb443102d23f33cd0a9cb5
https://doi.org/10.1016/j.molimm.2022.11.002
https://doi.org/10.1016/j.molimm.2022.11.002
Autor:
Axel Ullrich, György Kéri, Henrik Daub, István Szabadkai, László Őrfi, Yuri P. Knyazev, Kirti Sharma, Yuri V. Cheburkin, Peter G. Knyazev, Yi-Xiang Zhang
Supplementary Table 1 from AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69242eef7a4abffe5f9f345eac010ab4
https://doi.org/10.1158/0008-5472.22375325
https://doi.org/10.1158/0008-5472.22375325
Autor:
Axel Ullrich, György Kéri, Henrik Daub, István Szabadkai, László Őrfi, Yuri P. Knyazev, Kirti Sharma, Yuri V. Cheburkin, Peter G. Knyazev, Yi-Xiang Zhang
Supplementary Methods and Materials, Figures 1-5 from AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c655efb2408792af49402a78a819fa
https://doi.org/10.1158/0008-5472.22375328.v1
https://doi.org/10.1158/0008-5472.22375328.v1