Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laìs Pessanha de Carvalho"'
Autor:
Luka Krstulović, Vesna Rastija, Lais Pessanha de Carvalho, Jana Held, Zrinka Rajić, Zorislava Živković, Miroslav Bajić, Ljubica Glavaš-Obrovac
Publikováno v:
Molecules, Vol 29, Iss 13, p 2997 (2024)
Newly synthesized 7-chloro-4-aminoquinoline–benzimidazole hybrids were characterized by NMR and elemental analysis. Compounds were tested for their effects on the growth of the non-tumor cell line MRC-5 (human fetal lung fibroblasts) and carcinoma
Externí odkaz:
https://doaj.org/article/10989b5d69254f9ab784c39dddd36a84
Autor:
Dorothea Ekoka Mbassi, Ghyslain Mombo-Ngoma, Jana Held, Dearie Glory Okwu, Wilfrid Ndzebe-Ndoumba, Laura Charlotte Kalkman, Franck Aurelien Ekoka Mbassi, Lais Pessanha de Carvalho, Juliana Inoue, Malik Azeez Akinosho, Lia Betty Dimessa Mbadinga, Emmanuel Koffi Yovo, Benjamin Mordmüller, Peter Gottfried Kremsner, Ayôla Akim Adegnika, Michael Ramharter, Rella Zoleko-Manego
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104814- (2023)
Summary: Background: Ivermectin's mosquitocidal effect and in vitro activity against Plasmodium falciparum asexual stages are known. Its in vivo blood-schizonticidal efficacy is unknown. Ivermectin's tolerability and efficacy against P. falciparum in
Externí odkaz:
https://doaj.org/article/8ce2e823086b4bb9a68dd5d3ee383551
Autor:
Laís Pessanha de Carvalho, Sara Groeger-Otero, Andrea Kreidenweiss, Peter G. Kremsner, Benjamin Mordmüller, Jana Held
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Boromycin is a boron-containing macrolide antibiotic produced by Streptomyces antibioticus with potent activity against certain viruses, Gram-positive bacteria and protozoan parasites. Most antimalarial antibiotics affect plasmodial organelles of pro
Externí odkaz:
https://doaj.org/article/73f9ac4827c74b2c80871589bc1d71af
Publikováno v:
Molecules, Vol 26, Iss 8, p 2304 (2021)
Malaria is one of the most life-threatening infectious diseases and constitutes a major health problem, especially in Africa. Although artemisinin combination therapies remain efficacious to treat malaria, the emergence of resistant parasites emphasi
Externí odkaz:
https://doaj.org/article/358947099e564d1980836fac86664794
Autor:
Marina Marinović, Ivana Perković, Diana Fontinha, Miguel Prudêncio, Jana Held, Lais Pessanha de Carvalho, Tana Tandarić, Robert Vianello, Branka Zorc, Zrinka Rajić
Publikováno v:
Molecules, Vol 25, Iss 19, p 4376 (2020)
Harmicines represent hybrid compounds composed of β-carboline alkaloid harmine and cinnamic acid derivatives (CADs). In this paper we report the synthesis of amide-type harmicines and the evaluation of their biological activity. N-harmicines 5a–f
Externí odkaz:
https://doaj.org/article/0a56e61488f74a3da8ac621c3dd6b93e
Autor:
Walter Hofer, Emilia Oueis, Antoine Abou Fayad, Felix Deschner, Anastasia Andreas, Laìs Pessanha de Carvalho, Stephan Hüttel, Steffen Bernecker, Linda Pätzold, Bernd Morgenstern, Nestor Zaburannyi, Markus Bischoff, Marc Stadler, Jana Held, Jennifer Herrmann, Rolf Müller
Publikováno v:
Angewandte Chemie. 134
Autor:
Walter Hofer, Emilia Oueis, Antoine Abou Fayad, Felix Deschner, Anastasia Andreas, Laìs Pessanha de Carvalho, Stephan Hüttel, Steffen Bernecker, Linda Pätzold, Bernd Morgenstern, Nestor Zaburannyi, Markus Bischoff, Marc Stadler, Jana Held, Jennifer Herrmann, Rolf Müller
Publikováno v:
Angewandte Chemie (International ed. in English). 61(30)
The rise of antimicrobial resistance poses a severe threat to public health. The natural product chlorotonil was identified as a new antibiotic targeting multidrug resistant Gram-positive pathogens and Plasmodium falciparum. Although chlorotonil show