Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Laëtitia Gorisse"'
Autor:
Manon Doué, Anaïs Okwieka, Alexandre Berquand, Laëtitia Gorisse, Pascal Maurice, Frédéric Velard, Christine Terryn, Michaël Molinari, Laurent Duca, Christine Piétrement, Philippe Gillery, Stéphane Jaisson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Because of their long lifespan, matrix proteins of the vascular wall, such as elastin, are subjected to molecular aging characterized by non-enzymatic post-translational modifications, like carbamylation which results from the binding of cya
Externí odkaz:
https://doaj.org/article/7d9112e629014374850de6a0f738d8c7
Autor:
Sabine Trellu, Alice Courties, Stéphane Jaisson, Laëtitia Gorisse, Philippe Gillery, Saadia Kerdine-Römer, Carlos Vaamonde-Garcia, Xavier Houard, François-Paul Ekhirch, Alain Sautet, Bertrand Friguet, Claire Jacques, Francis Berenbaum, Jérémie Sellam
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme involved in the removal of AGE precursors, especially carboxymethyl-lysine (CML). We aime
Externí odkaz:
https://doaj.org/article/55cf3f1201fa4d44b0a2acf06a3d4799
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 574 (2022)
Carbamylation is a nonenzymatic post-translational modification resulting from the reaction between cyanate, a urea by-product, and proteins. In vivo and in vitro studies have demonstrated that carbamylation modifies protein structures and functions,
Externí odkaz:
https://doaj.org/article/9be8f54f6fae453f9ecd0b7d31f3ca6a
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82506 (2013)
Carbamylation is a general process involved in protein molecular ageing due to the nonenzymatic binding of isocyanic acid, mainly generated by urea dissociation, to free amino groups. In vitro experiments and clinical studies have suggested the poten
Externí odkaz:
https://doaj.org/article/9222d320f34d4b7c831552cff51fa7bf
Autor:
David B. Sacks, Andrew C. Hedman, Zhigang Li, Roland S. Annan, Dean E. McNulty, Laëtitia Gorisse
Publikováno v:
Journal of Biological Chemistry. 295:18105-18121
IQGAP1 is a key scaffold protein that regulates numerous cellular processes and signaling pathways. Analogous to many other cellular proteins, IQGAP1 undergoes post-translational modifications, including phosphorylation. Nevertheless, very little is
Publikováno v:
The Journal of biological chemistry. 298(5)
The Hippo signaling pathway regulates tissue growth and cell fate, and its dysregulation can induce tumorigenesis. When Hippo is activated by cell-cell contact, extracellular signals, or cell polarity among others, the large tumor suppressor 1 (LATS1
Autor:
Laurent Martiny, Sébastien Blaise, Alexandre Berquand, Laëtitia Gorisse, Philippe Gillery, Laurent Duca, Béatrice Romier-Crouzet, Pascal Maurice, Christine Pietrement, Fatouma Touré, Hervé Sartelet, Michael Molinari, Stéphane Jaisson, Aubéri Henry, Amar Bennasroune, Amandine Wahart
Publikováno v:
Nanoscale
Nanoscale, Royal Society of Chemistry, 2021, 13 (2), pp.1124-1133. ⟨10.1039/d0nr06753a⟩
Nanoscale, 2021, 13 (2), pp.1124-1133. ⟨10.1039/d0nr06753a⟩
Nanoscale, Royal Society of Chemistry, 2021, 13 (2), pp.1124-1133. ⟨10.1039/d0nr06753a⟩
Nanoscale, 2021, 13 (2), pp.1124-1133. ⟨10.1039/d0nr06753a⟩
International audience; Arterial stiffness is a complex process affecting the aortic tree that significantly contributes to cardiovascular diseases (systolic hypertension, coronary artery disease, heart failure or stroke). This process involves a lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9c19894ca953d6de87ecb3ae725316
https://hal.archives-ouvertes.fr/hal-03358064/document
https://hal.archives-ouvertes.fr/hal-03358064/document
Publikováno v:
Biochemical Journal. 475:3073-3086
Axl is a tyrosine kinase receptor that is important for hematopoiesis, the innate immune response, platelet aggregation, engulfment of apoptotic cells and cell survival. Binding of growth arrest-specific protein 6 (Gas6) activates Axl signaling, but
Publikováno v:
médecine/sciences. 33:176-182
Protein molecular aging corresponds to all modifications affecting proteins during their biological life, which lead to the alteration of their structural and functional properties. This phenomenon participates in cell and tissue aging and is therefo
Autor:
Stéphane Jaisson, Saadia Kerdine-Römer, Xavier Houard, Alain Sautet, Jérémie Sellam, Alice Courties, Bertrand Friguet, C. Jacques, Sabine Trellu, Philippe Gillery, Laëtitia Gorisse, Carlos Vaamonde-Garcia, Francis Berenbaum, François-Paul Ekhirch
Publikováno v:
Arthritis Research and Therapy
Arthritis Research and Therapy, BioMed Central, 2019, 21, pp.18. ⟨10.1186/s13075-018-1801-y⟩
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-12 (2019)
Arthritis Research and Therapy, BioMed Central, 2019, 21 (1), pp.18. ⟨10.1186/s13075-018-1801-y⟩
Arthritis Research and Therapy, 2019, 21, pp.18. ⟨10.1186/s13075-018-1801-y⟩
Arthritis Research and Therapy, BioMed Central, 2019, 21, pp.18. ⟨10.1186/s13075-018-1801-y⟩
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-12 (2019)
Arthritis Research and Therapy, BioMed Central, 2019, 21 (1), pp.18. ⟨10.1186/s13075-018-1801-y⟩
Arthritis Research and Therapy, 2019, 21, pp.18. ⟨10.1186/s13075-018-1801-y⟩
Background Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme involved in the removal of AGE precursors, especially carboxymethyl-lysine (CML). We aimed to inve