Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Laëtitia Cherel"'
Autor:
Christelle David, Nele Vandervoort, Damien Fleury, Denis Annoot, Laëtitia Cherel, Willem Jan Hengeveld, Thierry Christophe, Sameh H. Soror, Agnès Marie Joncour, Christopher Gaëtan Housseman, Alain Monjardet, R Galien, Patrick Mollat, Reginald Brys, Veronique Roncoroni, Luce Lepissier, Natacha Bienvenu, Lionel Vercheval, Alexandre Wohlkonig, Christophe Peixoto, Jörg Heiermann, Katja Conrath, Mia Jans, Sandrine Le Tallec, Bertrand Heckmann, Robert Touitou, Nicolas Desroy, Jan Steyaert, Virginie Labeguere, Gregor Pilzak, Ellen van der Aar, Xavier Marie Bock, Nicolas Triballeau, Emanuelle Wakselman
Publikováno v:
Journal of Medicinal Chemistry. 60:7371-7392
Autotaxin (ATX) is a secreted enzyme playing a major role in the production of lysophosphatidic acid (LPA) in blood through hydrolysis of lysophosphatidyl choline (LPC). The ATX-LPA signaling axis arouses a high interest in the drug discovery industr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bab957aedfbab6da364d90d0e33f16
https://doi.org/10.1021/acs.jmedchem.7b00647
https://doi.org/10.1021/acs.jmedchem.7b00647
Autor:
Elsa De Lemos, Vanessa Quenehen, Laëtitia Cherel, Nicolas Triballeau, Reginald Brys, Stéphane Beaumont, Florilène Soulas, Murielle Manioc, Thierry Christophe, Emanuelle Wakselman, Ellen van der Aar, Natacha Bienvenu, Christelle L’Ebraly, Luc Nelles, Line Oste, Laurent Saniere, Fatoumata Djata, Stéphanie Lavazais, Philippe Delerive, Stephen Robert Fletcher, Steve De Vos, Mathieu Rafaël Pizzonero, Sabrina Kopiejewski, S. Dupont, Nick Vandeghinste, Jean-Michel Lefrancois, Benedetta Crescenzi, Denis Polancec, Marielle Babel, Pierre Deprez, Roland Blanque
Publikováno v:
Journal of Medicinal Chemistry. 57:10044-10057
FFA2, also called GPR43, is a G-protein coupled receptor for short chain fatty acids which is involved in the mediation of inflammatory responses. A class of azetidines was developed as potent FFA2 antagonists. Multiparametric optimization of early h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33097c7d0222ebea1a74983132fa64b7
https://doi.org/10.1021/jm5012885
https://doi.org/10.1021/jm5012885
Autor:
Nele Vandervoort, Xavier Marie Bock, Patrick Mollat, Jovica Ralić, Alain Monjardet, Nicolas Triballeau, Thierry Christophe, Ellen van der Aar, Marieke Lamers, Boska Hrvacic, Nicolas Desroy, Bertrand Heckmann, Line Oste, Emilie Rondet, Virginie Labeguere, Roland Blanque, Veronique Roncoroni, Christopher Gaëtan Housseman, Sandrine Le Tallec, Natacha Bienvenu, C. Cottereaux, M. Auberval, Reginald Brys, Laëtitia Cherel, Emanuelle Wakselman, Picolet Olivier Laurent, Jean-Marie Grassot, Agnès Marie Joncour, Christophe Peixoto, Denis Annoot
Autotaxin is a circulating enzyme with a major role in the production of lysophosphatic acid (LPA) species in blood. A role for the autotaxin/LPA axis has been suggested in many disease areas including pulmonary fibrosis. Structural modifications of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c6f6e80895c7ca93e77aad9243c383
https://www.bib.irb.hr/981523
https://www.bib.irb.hr/981523
Autor:
Reginald Brys, Emanuelle Wakselman, Lionel Vercheval, Christelle David, Nele Vandervoort, Laëtitia Cherel, Christopher Gaëtan Housseman, Luce Lepissier, Natacha Bienvenu, Mia Jans, Alain Monjardet, Agnès Marie Joncour, Nicolas Desroy, Gregor Pilzak, Willem Jan Hengeveld, Sandrine Le Tallec, Ellen van der Aar, Bertrand Heckmann, Nicolas Triballeau, Jan Steyaert, Patrick Mollat, Veronique Roncoroni, Virginie Labeguere, Sameh H. Soror, Damien Fleury, Thierry Christophe, Christophe Peixoto, Xavier Marie Bock, Denis Annoot, Jörg Heiermann, Katja Conrath, R Galien, Robert Touitou, Alexandre Wohlkonig
Publikováno v:
Journal of Medicinal Chemistry. 61:4270-4270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93dee812f5866eca6cabf47d605a46ce
https://doi.org/10.1021/acs.jmedchem.8b00579
https://doi.org/10.1021/acs.jmedchem.8b00579