Zobrazeno 1 - 4
of 4
pro vyhledávání: '"LY-293284"'
Publikováno v:
Psychopharmacology. 172:415-421
Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug with a low incidence of side effects. The therapeutic action of aripiprazole has been attributed to its unique agonist/antagonist effects at D(2) dopamine receptors; however, aripiprazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99990a59a65389a6bf8157c8944e25a3
https://doi.org/10.1007/s00213-003-1677-6
https://doi.org/10.1007/s00213-003-1677-6
Autor:
Deborah M. Kurrasch-Orbaugh, Medhane G. Cumbay, Danuta Marona-Lewicka, Jennifer Selken, Joshua G. Lisnicchia, David E. Nichols
Publikováno v:
Psychopharmacology. 164:93-107
Rationale. There is substantial evidence that lisuride can produce effects linked to 5-HT1A receptor occupancy. Nevertheless, this action has generally been ignored in the mechanism of action of lisuride, in favor of an exclusive role for dopamine re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8f64e76c2d6273eccb3b9caf7db29a
https://doi.org/10.1007/s00213-002-1141-z
https://doi.org/10.1007/s00213-002-1141-z
Autor:
Val J. Watts, Danuta Marona-Lewicka, Joseph B. Blair, Eric L. Barker, David E. Nichols, Deborah M. Kurrasch-Orbaugh, Medhane G. Cumbay
Publikováno v:
Journal of medicinal chemistry. 43(24)
A series of fluorinated analogues of the hallucinogenic tryptamines N,N-diethyltryptamine (DET), 4-hydroxy-N,N-dimethyltryptamine (4-OH-DMT, psilocin), and 5-methoxy-DMT was synthesized to investigate possible explanations for the inactivity of 6-flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55ad31c384e9e77617b589a1b378136
https://pubmed.ncbi.nlm.nih.gov/11101361
https://pubmed.ncbi.nlm.nih.gov/11101361
Autor:
B.-J. Cao, R.J. Rodgers
Publikováno v:
Psychopharmacology. 139(3)
In contrast to the variable efficacy of 5-HT1A receptor full and partial agonists in animal models of anxiety, recent findings in our laboratory have revealed remarkably consistent anxiolytic-like effects for 5-HT1A receptor antagonists in the murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271971838b6b4dd79cb0ea677ec8b59a
https://pubmed.ncbi.nlm.nih.gov/9784072
https://pubmed.ncbi.nlm.nih.gov/9784072