Zobrazeno 1 - 10
of 174
pro vyhledávání: '"LV, Wain"'
Publikováno v:
‘Scar Wars’ – The pot pourri of ILD.
Autor:
RJ Allen, JM Oldham, DA Jenkins, OC Leavy, B Guillen-Guio, CA Melbourne, SF Ma, J Jou, JS Kim, WA Fahy, E Oballa, RB Hubbard, V Navaratnam, R Braybrooke, G Saini, KM Roach, MD Tobin, N Hirani, MKB Whyte, N Kaminski, Y Zhang, FJ Martinez, AL Linderholm, A Adegunsoye, ME Strek, TM Maher, PL Molyneaux, C Flores, I Noth, RG Jenkins, LV Wain
Publikováno v:
‘Beyond the Matrix’ – Fibroblast biology.
Autor:
B Guillen-Guio, RJ Allen, OC Leavy, T Hernández-Beeftink, E Suarez-Pajes, RG Jenkins, C Flores, LV Wain
Publikováno v:
Joint BTS/BALR/A+L UK Early Career Investigator Symposium.
Autor:
R Packer, AT Williams, W Hennah, MT Eisenberg, KA Fawcett, W Pearson, A Guyatt, A Edris, EJ Hollox, BS Rao, JR Bratty, LV Wain, F Dudbridge, MD Tobin
SummaryDeepPheWAS is an R package for phenome wide association studies that creates clinically-curated composite phenotypes, and integrates quantitative phenotypes from primary care data, longitudinal trajectories of quantitative measures, disease pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947e55a7e2a270de34393d5e555f30e8
https://doi.org/10.1101/2022.05.05.22274419
https://doi.org/10.1101/2022.05.05.22274419
Autor:
I Stewart, J Jacob, PM George, PL Molyneaux, JC Porter, RJ Allen, JK Baillie, SL Barratt, P Beirne, SM Bianchi, JF Blaikley, J Chalmers, RC Chambers, N Chadhuri, C Coleman, G Collier, EK Denneny, A Docherty, O Elneima, RA Evans, L Fabbri, MA Gibbons, FV Gleeson, B Gooptu, NJ Greening, B Guillen Guio, IP Hall, NA Hanley, V Harris, EM Harrison, M Heightman, TE Hillman, A Horsley, L Houchen-Wolloff, I Jarrold, SR Johnson, MG Jones, F Khan, R Lawson, OC Leavy, N Lone, M Marks, H McAuley, P Mehta, E Omer, D Parekh, K Piper Hanley, M Platé, J Pearl, K Poinasamy, JK Quint, B Raman, M Richardson, P Rivera-Ortega, LC Saunders, R Saunders, MG Semple, M Sereno, A Shikotra, AJ Simpson, A Singapuri, DJF Smith, M Spears, LG Spencer, S Stanel, D Thickett, AAR Thompson, M Thorpe, R Thwaites, SLF Walsh, S Walker, ND Weatherley, M Weeks, JM Wild, DG Wootton, CE Brightling, LP Ho, LV Wain, RG Jenkins
IntroductionShared characteristics between COVID-19 and pulmonary fibrosis, including symptoms, genetic architecture, and circulating biomarkers, suggests interstitial lung disease (ILD) development may be associated with SARS-CoV-2 infection.Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e505b56f7f35a187d4185f499c48222
https://doi.org/10.1101/2022.03.10.22272081
https://doi.org/10.1101/2022.03.10.22272081
Autor:
RJ Packer, N Shrine, R Hall, CA Melbourne, R Thompson, AT Williams, ML Paynton, AL Guyatt, PH Lee, C John, A Campbell, C Hayward, M de Vries, JM Vonk, J Davitte, E Hessel, D Michalovich, JC Betts, I Sayers, A Yeo, IP Hall, MD Tobin, LV Wain
BackgroundChronic sputum production impacts on quality of life and is a feature of many respiratory diseases. Identification of the genetic variants associated with chronic sputum production in a disease agnostic sample could improve understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0807dee241dc34e2c14db70ea93cc92b
https://doi.org/10.1101/2022.01.11.22269075
https://doi.org/10.1101/2022.01.11.22269075
Autor:
E, Repapi, I, Sayers, LV, Wain, RB, Burton, T, Johnson, M, Obeidat, JH, Zhao, A, Ramasamy, G, Zhai, V, Vitart, JE, Huffman, W, Igl, E, Albrecht, P, Deloukas, J, Henderson, J, Granell, WL, McArdle, AR, Rudnicka, Consortium, Wellcome Trust Case Control, I, Barroso, RJF, Loos, NJ, Wareham, L, Mustelin, Rantanen, Taina, I, Surakka, M, Imboden, HE, Wichmann, I, Grkovic, S, Jankovic, L, Zgaga, A, Hartikainen, L, Peltonen, U, Gyllensten, Å, Johansson, G, Zaboli, H, Campbell, SH, Wild, JF, Wilson, S, Gläser, G, Homuth, H, Völzke, M, Mangino, N, Soranzo, TD, Spector, O, Polašek, I, Rudan, AF, Wright, M, Heliövaara, S, Ripatti, A, Pouta, Å, Torinsson Naluai, A, Olin, K, Torén, MN, Cooper, AL, James, LJ, Palmer, AD, Hingorani, SG, Wannamethee, PH, Whincup, GD, Smith, S, Ebrahim, TM, McKeever, ID, Pavord, AK, MacLeod, AD, Morris, DJ, Porteous, C, Cooper, E, Dennison, S, Shaheen, S, Karrasch, E, Schnabel, H, Schulz, H, Grallert, N, Bouatia-Naji, J, Delplanque, P, Froguel, JD, Blakey, Team, The NSHD Respiratory Study, JR, Britton, RW, Morris, JW, Holloway, DA, Lawlor, J, Hui, F, Nyberg, M, Jarvelin, C, Jackson, M, Kähönen, J, Kaprio, NM, Probst-Hensch, B, Koch, C, Hayward, DE, Evans, P, Elliott, DP, Strachan, IP, Hall, MD, Tobin
Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1222::aefe3de804274fbd8ed1dba5a61e3a7f
http://urn.fi/URN:NBN:fi:jyu-201909184206
http://urn.fi/URN:NBN:fi:jyu-201909184206
Autor:
Soler Artigas M, Dw, Loth, Lv, Wain, Sa, Gharib, Obeidat M, Tang W, Zhai G, Jh, Zhao, Av, Smith, Je, Huffman, Albrecht E, Cm, Jackson, Dm, Evans, Cadby G, Md, Tobin
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ca1cc8fb6ef3ea02043db674769307f
http://europepmc.org/abstract/med/21946350
http://europepmc.org/abstract/med/21946350
Autor:
Leavy OC; Department of Population Health Sciences, University of Leicester, Leicester, UK.; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; These authors contributed equally., Russell RJ; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; These authors contributed equally., Harrison EM; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Lone NI; The Usher Institute, University of Edinburgh, Edinburgh, UK.; Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, UK., Kerr S; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.; Roslin Institute, University of Edinburgh, Edinburgh, UK., Docherty AB; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Sheikh A; The Usher Institute, University of Edinburgh, Edinburgh, UK., Richardson M; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Elneima O; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Greening NJ; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Harris VC; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK., Houchen-Wolloff L; Centre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Therapy Department, University Hospitals of Leicester, NHS Trust, Leicester, UK., McAuley HJC; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Saunders RM; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Sereno M; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Shikotra A; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Singapuri A; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Aul R; St George's University Hospitals NHS Foundation Trust, London, UK., Beirne P; The Leeds Teaching Hospitals NHS Trust, Leeds, UK., Bolton CE; University of Nottingham, Nottingham, UK.; Nottingham University Hospitals NHS Trust, Nottingham, UK.; NIHR Nottingham Biomedical Research Centre, Nottingham, UK., Brown JS; UCL Respiratory, Department of Medicine, University College London, Rayne Institute, London, UK., Choudhury G; University of Edinburgh, Edinburgh, UK.; NHS Lothian, Edinburgh, UK., Diar Bakerly N; Manchester Metropolitan University, Manchester, UK.; Salford Royal NHS Foundation Trust, Manchester, UK., Easom N; Infection Research Group, Hull University Teaching Hospitals, Hull, UK.; University of Hull, Hull, UK., Echevarria C; The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Fuld J; Department of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; University of Cambridge, Cambridge, UK.; NIHR Cambridge Clinical Research Facility, Cambridge, UK., Hart N; Lane Fox Respiratory Service, Guy's and St Thomas NHS Foundation Trust, London, UK., Hurst JR; University College London, London, UK.; Royal Free London NHS Foundation Trust, London, UK., Jones M; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; NIHR Southampton Biomedical Research Centre, University Hospitals Southampton, Southampton, UK., Parekh D; University of Birmingham, Birmingham, UK.; University Hospital Birmingham NHS Foundation Trust, Birmingham, UK., Pfeffer P; Barts Health NHS Trust, London, UK.; Queen Mary University of London, London, UK., Rahman NM; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK.; CAMS Oxford Institute, Oxford, UK., Rowland-Jones S; University of Sheffield, Sheffield, UK.; Sheffield Teaching NHS Foundation Trust, Sheffield, UK., Shah AM; Kings College London, London, UK.; Kings College London NHS Foundation Trust, London, UK., Wootton DG; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Liverpool, Liverpool, UK., Jolley C; Kings College London, London, UK.; Kings College London NHS Foundation Trust, London, UK., Thompson AAR; University of Sheffield, Sheffield, UK.; Sheffield Teaching NHS Foundation Trust, Sheffield, UK., Chalder T; Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.; South London and Maudsley NHS Trust, London, UK., Davies MJ; University Hospitals of Leicester NHS Trust, Leicester, UK.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; Diabetes Research Centre, University of Leicester, Leicester, UK., De Soyza A; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.; Newcastle upon Tyne Teaching Hospitals Trust, Newcastle upon Tyne, UK., Geddes JR; NIHR Oxford Health Biomedical Research Centre, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Oxford, UK., Greenhalf W; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.; University of Liverpool, Liverpool, UK.; The CRUK Liverpool Experimental Cancer Medicine Centre, Liverpool, UK., Heller S; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK., Howard L; Imperial College Healthcare NHS Trust, London, UK.; Imperial College London, London, UK., Jacob J; Centre for Medical Image Computing, University College London, London, UK.; Lungs for Living Research Centre, University College London, London, UK., Jenkins RG; National Heart and Lung Institute, Imperial College London, London, UK., Lord JM; MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; NIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham and the University of Birmingham, Birmingham, UK., Man WD; Royal Brompton and Harefield Clinical Group, Guy's and St Thomas NHS Foundation Trust, London, UK.; NHLI, Imperial College London, London, UK., McCann GP; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Neubauer S; NIHR Oxford Health Biomedical Research Centre, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK., Porter J; UCL Respiratory, Department of Medicine, University College London, Rayne Institute, London, UK.; ILD Service, University College London Hospital, London, UK., Rowland MJ; Kadoorie Centre for Critical Care Research, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Scott JT; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK., Semple MG; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.; Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, UK., Singh SJ; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Thomas D; Imperial College London, London, UK., Toshner M; NIHR Cambridge Clinical Research Facility, Cambridge, UK.; Cambridge NIHR BRC, Cambridge, UK., Lewis K; Hywel Dda University Health Board, Wales, UK.; University of Swansea, Wales, UK.; Respiratory Innovation Wales, Wales, UK., Heaney LG; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.; Belfast Health and Social Care Trust, Belfast, UK., Briggs A; London School of Hygiene and Tropical Medicine, London, UK., Zheng B; London School of Hygiene and Tropical Medicine, London, UK., Thorpe M; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Quint JK; NHLI, Imperial College London, London, UK., Chalmers JD; University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Ho LP; NIHR Oxford Biomedical Research Centre, Oxford, UK.; MRC Human Immunology Unit, University of Oxford, Oxford, UK., Horsley A; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Manchester University NHS Foundation Trust, Manchester, UK., Marks M; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.; Hospital for Tropical Diseases, University College London Hospital, London, UK.; Division of Infection and Immunity, University College London, London, UK., Poinasamy K; Asthma and Lung UK, London, UK., Raman B; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Brightling CE; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Evans RA; The Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.
Publikováno v:
ERJ open research [ERJ Open Res] 2024 Sep 30; Vol. 10 (5). Date of Electronic Publication: 2024 Sep 30 (Print Publication: 2024).
Autor:
Taquet M; Department of Psychiatry, University of Oxford, Oxford, UK; Oxford Health NHS Foundation Trust, Oxford, UK; NIHR Oxford Health Biomedical Research Centre, Oxford, UK. Electronic address: maxime.taquet@msd.ox.ac.uk., Skorniewska Z; Department of Psychiatry, University of Oxford, Oxford, UK; NIHR Oxford Health Biomedical Research Centre, Oxford, UK., De Deyn T; Department of Psychiatry, University of Oxford, Oxford, UK., Hampshire A; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Trender WR; Department of Brain Sciences, Imperial College London, London, UK., Hellyer PJ; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Chalmers JD; University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Ho LP; MRC Translational Immune Discovery Unit, University of Oxford, Oxford, UK., Horsley A; Division of Infection, Immunity & Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Manchester University NHS Foundation Trust, Manchester, UK., Marks M; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK; Hospital for Tropical Diseases, University College London Hospital, London, UK; Division of Infection and Immunity, University College London, London, UK., Poinasamy K; Asthma and Lung UK, London, UK., Raman B; Radcliffe Department of Medicine, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Leavy OC; Department of Population Health Sciences, University of Leicester, Leicester, UK., Richardson M; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Elneima O; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., McAuley HJC; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Shikotra A; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Singapuri A; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Sereno M; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Saunders RM; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Harris VC; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Rogers N; Long Covid Support, England and Wales, UK., Houchen-Wolloff L; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK; Therapy Department, University Hospitals of Leicester NHS Trust, Leicester, UK., Greening NJ; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK., Mansoori P; MQ: Transforming Mental Health, London, UK., Harrison EM; Centre for Medical Informatics, University of Edinburgh, Edinburgh, UK., Docherty AB; Centre for Medical Informatics, University of Edinburgh, Edinburgh, UK., Lone NI; Population Health Sciences, The Usher Institute, University of Edinburgh, Edinburgh, UK; Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, UK., Quint J; National Heart and Lung Institute, Imperial College London, London, UK., Brightling CE; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Evans RA; The Institute for Lung Health, Department of Respiratory Sciences, University of Leicester, Leicester, UK; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Geddes JR; Department of Psychiatry, University of Oxford, Oxford, UK; Oxford Health NHS Foundation Trust, Oxford, UK; NIHR Oxford Health Biomedical Research Centre, Oxford, UK., Harrison PJ; Department of Psychiatry, University of Oxford, Oxford, UK; Oxford Health NHS Foundation Trust, Oxford, UK; NIHR Oxford Health Biomedical Research Centre, Oxford, UK.
Publikováno v:
The lancet. Psychiatry [Lancet Psychiatry] 2024 Sep; Vol. 11 (9), pp. 696-708. Date of Electronic Publication: 2024 Jul 31.