Zobrazeno 1 - 10
of 34
pro vyhledávání: '"LUIZA R.S. DIAS"'
Autor:
RAQUEL R.S. SALVADOR, MURILO L. BELLO, IGOR R.L. BARRETO, MARIA A.F. VERA, ESTELA M.F. MURI, SÉRGIO DE ALBUQUERQUE, LUIZA R.S. DIAS
Publikováno v:
Anais da Academia Brasileira de Ciências, Iss 0
ABSTRACT This paper reports the in vitro trypanocidal activity evaluation of new carbohydrazide derivatives from 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine, substituted at C-6 position by phenyl, methyl or trifluoromethyl group. These compounds wer
Externí odkaz:
https://doaj.org/article/e9ebd4f728da48ed83c5b83a72f04335
Autor:
SIMONE S.S. OLIVEIRA, MURILO L. BELLO, CARLOS R. RODRIGUES, PAULA L. DE AZEVEDO, MARIA C.K.V. RAMOS, FRANCISCO R. DE AQUINO-NETO, SORELE B. FIAUX, LUIZA R.S. DIAS
Publikováno v:
Anais da Academia Brasileira de Ciências, Iss 0
ABSTRACT This study presents the bioreduction of six β-ketoesters by whole cells of Kluyveromyces marxianus and molecular investigation of a series of 13 β-ketoesters by hologram quantitative structure-activity relationship (HQSAR) in order to rela
Externí odkaz:
https://doaj.org/article/6345130ea2a244668eafbc4bc0c0f902
Autor:
Sergio Pinheiro, Estela M.F. Muri, Barbara D.C. Pacheco, Luciano Puzer, Bruno E.G. de Souza, Mariana B.M. de Moraes, Rafael Garrett, Luiza R.S. Dias, Camilo Henrique da Silva Lima, Acácio S. de Souza
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:1094-1098
Human kallikreins 5 and 7 (KLK5 and KLK7) exhibit trypsin- and chymotrypsin-like activities and are involved in pathologies related to skin desquamation process. A series of new 3-acyltetramic acids were developed as a novel class of inhibitors of KL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1e0b1e355711c876cc50db063e0c1d
https://doi.org/10.1016/j.bmcl.2019.02.031
https://doi.org/10.1016/j.bmcl.2019.02.031
Autor:
Gisele Bulhões Portapilla, Luiza R.S. Dias, Júlio C. A. V. Soares, Estela M.F. Muri, Camilo Henrique da Silva Lima, Maiara Voltarelli Providello, Sérgio de Albuquerque, Joana Lucius de Sousa Ribeiro
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Despite the serious public health problems caused by Chagas disease in several countries, the available therapy remains with only two drugs that are poorly active during the chronic phase of the disease in addition to having severe side effects. In s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326202b3ea4243d9053566a539950666
Autor:
Luiz A.P. Flores-Junior, Luiza R.S. Dias, Sueli Fumie Yamada-Ogatta, Priscila Goes Camargo, Lucy Megumi Yamauchi Lioni, Phileno Pinge-Filho, Camilo Henrique da Silva Lima, Bruna Terci Fernandes, Patrícia Mendes Pereira, Fernando Macedo, Marcelle de Lima Ferreira Bispo
Publikováno v:
Parasitology international. 80
A series of sixteen benzoylthioureas derivatives were initially evaluated in vitro against the epimastigote form of Trypanosoma cruzi. All of the tested compounds inhibited the growth of this form of the parasite, and due to the promising anti-epimas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9e306747afb747d25b3c49461a6585
https://pubmed.ncbi.nlm.nih.gov/33160050
https://pubmed.ncbi.nlm.nih.gov/33160050
Autor:
Thalita G. Barros, Luiz A.P. Flores-Junior, Luiza R.S. Dias, Suraby O. Albuquerque, Wagner B. Dias, Hector F. Loponte, Estela M.F. Muri, Adriane R. Todeschini, Eldio Gonçalves dos Santos, Pedro H.R. de A. Azevedo, Sergio Pinheiro, Camilo Henrique da Silva Lima
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 154
The vital enzyme O-linked β-N-acetylglucosamine transferase (OGT) catalyzes the O-GlcNAcylation of intracellular proteins coupling the metabolic status to cellular signaling and transcription pathways. Aberrant levels of O-GlcNAc and OGT have been l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f66e30097ae364ada6794e40adf5cf
https://pubmed.ncbi.nlm.nih.gov/32801002
https://pubmed.ncbi.nlm.nih.gov/32801002
Autor:
Camilo Henrique da Silva Lima, Sérgio de Albuquerque, Luiza R.S. Dias, Estela M.F. Muri, Júlio C. A. V. Soares, Joana Lucius de Sousa Ribeiro
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background: Untargeted studies led to the development of some pyrazolopyridine derivatives for the antiparasitic profile, particularly the derivatives containing the structural carbohydrazide subunit. In this work, we proceeded in the biological scre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86b46223b6cc263a143798113b70133
Autor:
Lucas Villas Bôas Hoelz, Marcelo B. Zani, Lucas R. de Souza, Luiza R.S. Dias, Sergio Pinheiro, Silvia G. Passos, Bruna C. Zorzanelli, Pedro H.R. de A. Azevedo, Luciano Puzer, Estela M.F. Muri
Publikováno v:
European Journal of Medicinal Chemistry. 112:39-47
Human kallikrein 5 (KLK5) is a potential target for the treatment of skin inflammation and cancer. A new series of statine based peptidomimetic compounds were designed and synthesized through simple and efficient reactions. Some KLK5 inhibitors (2a-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6abb669a29bd6ae72c32310f6f5760
https://doi.org/10.1016/j.ejmech.2016.01.060
https://doi.org/10.1016/j.ejmech.2016.01.060
Autor:
Júlio C. A. V. Soares, Luiza R.S. Dias
Publikováno v:
Molbank, Vol 2020, Iss 1, p M1104 (2020)
Synthesis of N′-acetyl-3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide from the phenyl acetates of 3-acetyl-5-(3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine-4-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl in alkaline medium and its char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9f11afc5c78f92a8a3b861f8da4d20
https://doi.org/10.3390/m1104
https://doi.org/10.3390/m1104
Autor:
Júlio C. A. V. Soares, Luiza R.S. Dias, Gisele Bulhões Portapilla, Sérgio de Albuquerque, Joana Lucius de Sousa Ribeiro, Camilo Henrique da Silva Lima
Publikováno v:
Proceedings of 4th International Electronic Conference on Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78164af602edac06cdc321739d190988
https://doi.org/10.3390/ecmc-4-05610
https://doi.org/10.3390/ecmc-4-05610