Zobrazeno 1 - 10
of 39
pro vyhledávání: '"LUCIO M. CABRAL"'
Autor:
MARCELE C.C. DA SILVA, LETÍCIA C.L. DE ABREU, FLAVIA A. DO CARMO, CARLOS R. RODRIGUES, VALERIA P. DE SOUSA, LUCIO M. CABRAL
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 94, Iss suppl 3 (2022)
Abstract The concern about the risks of viral infections transmission through blood transfusion has led into a search for improvements on screening tests used for the selection of blood donors. Molecular biology techniques applied in researches of vi
Externí odkaz:
https://doaj.org/article/03923ba69e424d1fbb0ebf94f569217b
Autor:
JÉSSICA B. DE JESUS, RAISSA A. DA CONCEIÇÃO, THAYNÁ R. MACHADO, MARIA L.C. BARBOSA, THAISA F.S. DOMINGOS, LUCIO M. CABRAL, CARLOS R. RODRIGUES, BÁRBARA ABRAHIM-VIEIRA, ALESSANDRA M.T. DE SOUZA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 94, Iss suppl 3 (2022)
Abstract Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are the latest class of drugs approved to treat type 2 DM (T2DM). Although adverse effects are often caused by a metabolite rather than the drug itself, only the safety assessment of disprop
Externí odkaz:
https://doaj.org/article/d7315ccc43f24e79baf2d5d9959383c4
Autor:
Elisangela da Costa Lima, Guacira Corrêa de Matos, Jean M. de L. Vieira, Ivana C. da C.R. Gonçalves, Lucio M. Cabral, Mark A. Turner
Publikováno v:
Jornal de Pediatria (Versão em Português), Vol 95, Iss 6, Pp 682-688 (2019)
Objective: To assess spontaneous reports of suspected adverse drug reactions in children aged 0‐12 years from the Brazilian Health Regulatory Agency between 2008 and 2013. Methods: A cross‐sectional study on suspected adverse drug reactions repor
Externí odkaz:
https://doaj.org/article/19fa3d64b932400db866dea12e862814
Autor:
Gleyton Sousa, Maria C. F. de Almeida, Lucas L. Lócio, Vanda L. dos Santos, Daniel P. Bezerra, Valdenizia R. Silva, Sinara M. V. de Almeida, Alice Simon, Thiago da S. Honório, Lucio M. Cabral, Rosane N. Castro, Ricardo O. de Moura, Arthur E. Kümmerle
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1098 (2022)
In this study, we report the synthesis of twenty new acridine–thiosemicarbazone derivatives and their antiproliferative activities. Mechanisms of action such as the inhibition of topoisomerase IIα and the interaction with DNA have been studied for
Externí odkaz:
https://doaj.org/article/b34c6a67d6bd4f02a04b3f2a8b81145f
Autor:
BARBÁRA A. ABRAHIM-VIEIRA, ALESSANDRA M.T. DE SOUZA, RITA C. BARROS, FLÁVIA A. DO CARMO, LETÍCIA C.L. DE ABREU, RONYSON S.S. MOREIRA, THIAGO S. HONÓRIO, CARLOS R. RODRIGUES, VALERIA P. DE SOUSA, LUCIO M. CABRAL
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 92, Iss 2 (2020)
Abstract Sildenafil is a potent selective inhibitor of phosphosdiesterase-5 previously used in erectile dysfunction and subsequently approved in 2005 for pulmonary arterial hypertension treatment. Since oral administration of sildenafil shows pharmac
Externí odkaz:
https://doaj.org/article/3ebcc8a015384daaaf5f73f18af76622
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 90, Iss 3, Pp 3063-3073 (2018)
Abstract Dietary supplements in many countries such as the USA do not require registration prior to commercialization. The Agência Nacional de Vigilância Sanitária (ANVISA) registers substances with functional properties as foods. Lutein is a caro
Externí odkaz:
https://doaj.org/article/5a94f27aae99421e85d8544a2dec1502
Autor:
Juliana F. R. Mello, Nathália C. Botelho, Alessandra M. T. Souza, Riethe Oliveira, Monique A. Brito, Bárbara de A. Abrahim-Vieira, Ana Carolina R. Sodero, Helena C. Castro, Lucio M. Cabral, Leonardo A. Miceli, Carlos R. Rodrigues
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 10689-10704 (2015)
Herpes simplex virus infections have been described in the medical literature for centuries, yet the the drugs available nowadays for therapy are largely ineffective and low oral bioavailability plays an important role on the inefficacy of the treatm
Externí odkaz:
https://doaj.org/article/4c44b936310b4d6fb14b26f34c18c6d2
Autor:
Reinaldo Barros Geraldo, Plínio Cunha Sathler, André Luiz Lourenço, Max Seidy Saito, Lucio M. Cabral, Pabulo Henrique Rampelotto, Helena Carla Castro
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17901-17919 (2014)
Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designi
Externí odkaz:
https://doaj.org/article/7cd7ae0eb232496f9f7fac19510cae65
Autor:
Alessandra M. T. de Souza, Monique A. de Brito, Lucio M. Cabral, Magaly G. Albuquerque, Juliana F. R. Mello, Carlos R. Rodrigues, Helena C. Castro, Valéria L. Teixeira, Leonardo A. Miceli
Publikováno v:
Marine Drugs, Vol 11, Iss 11, Pp 4127-4143 (2013)
AIDS is a pandemic responsible for more than 35 million deaths. The emergence of resistant mutations due to drug use is the biggest cause of treatment failure. Marine organisms are sources of different molecules, some of which offer promising HIV-1 r
Externí odkaz:
https://doaj.org/article/c442a40fee734ba7bf5ad88d16760c9b
Autor:
Camila B. Dornelas, Daniel K. Resende, Helvecio V. A. Rocha, Ailton S. Gomes, Maria Inês B. Tavares, Sandra S. S. Coutinho, Lucio M. Cabral
Publikováno v:
Polímeros, Vol 18, Iss 3, Pp 222-229 (2008)
A nanotecnologia está relacionada às estruturas, propriedades e processos envolvendo materiais com dimensões numa escala nanométrica. O conceito de nanotecnologia em aplicações farmacêuticas, mais especificamente na liberação de fármacos, e
Externí odkaz:
https://doaj.org/article/239ac54eef724dd3a72b6a2164284597