Zobrazeno 1 - 10
of 207
pro vyhledávání: '"LTP (long term potentiation)"'
Autor:
Gonzalo Valdivia, Alvaro O. Ardiles, Abimbola Idowu, Claudia Salazar, Hey-Kyoung Lee, Michela Gallagher, Adrian G. Palacios, Alfredo Kirkwood
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 15 (2023)
Long-term potentiation (LTP) and depression (LTD) are currently the most comprehensive models of synaptic plasticity models to subserve learning and memory. In the CA1 region of the hippocampus LTP and LTD can be induced by the activation of either N
Externí odkaz:
https://doaj.org/article/468561cadf704e42872711578eef54fc
Autor:
Fouad Lemtiri-Chlieh, Eric S. Levine
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
It is widely accepted that exogenous cannabinoids can impair short-term memory and cognition in humans and other animals. This is likely related to the inhibition of long-term potentiation (LTP), a form of synaptic plasticity, by the global and susta
Externí odkaz:
https://doaj.org/article/a94063381a164284a4dc07798058ab1e
Autor:
John B. Butcher, Robert E. Sims, Neville M. Ngum, Amjad H. Bazzari, Stuart I. Jenkins, Marianne King, Eric J. Hill, David A. Nagel, Kevin Fox, H. Rheinallt Parri, Stanislaw Glazewski
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Changes to sensory experience result in plasticity of synapses in the cortex. This experience-dependent plasticity (EDP) is a fundamental property of the brain. Yet, while much is known about neuronal roles in EDP, very little is known about the role
Externí odkaz:
https://doaj.org/article/edf2e7f467bd4acea65c5f1df397e466
Autor:
Aeen Ebrahim Amini, Tsukiko Miyata, Gang Lei, Fuzi Jin, Elizabeth Rubie, Clarrisa A. Bradley, James R. Woodgett, Graham L. Collingridge, John Georgiou
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Glycogen synthase kinase-3 (GSK3) mediates phosphorylation of several hundred proteins, and its aberrant activity is associated with an array of prevalent disorders. The two paralogs, GSK3α and GSK3β, are expressed ubiquitously and fulfill common a
Externí odkaz:
https://doaj.org/article/f810d1a6561e4cd399ff5c0972d0106d
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Synaptic plasticity is a critical process that regulates neuronal activity by allowing neurons to adjust their synaptic strength in response to changes in activity. Despite the high proximity of excitatory glutamatergic and inhibitory GABAergic posts
Externí odkaz:
https://doaj.org/article/2dd381a46d564a9f8f261f82a32f7f50
Autor:
Trine Waage Rygvold, Christoffer Hatlestad-Hall, Torbjørn Elvsåshagen, Torgeir Moberget, Stein Andersson
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
Long-term potentiation (LTP) is one of the most extensively studied forms of neuroplasticity and is considered the strongest candidate mechanism for memory and learning. The use of event-related potentials and sensory stimulation paradigms has allowe
Externí odkaz:
https://doaj.org/article/73b171e184104e898fd0b7e9660d9a08
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Huntington’s disease (HD) is an inherited neurodegenerative disorder characterized by neuronal loss and tissue atrophy mainly in the striatum and cortex. In the early stages of the disease, impairment of neuronal function, synaptic dysfunction and
Externí odkaz:
https://doaj.org/article/a2319712680544fca900d3b65930a9f1
Autor:
Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Nozomu Masuyama, Ayaka Notoya, Shinya Ueno
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: Gamma-aminobutyric acid (GABA) type A receptors are positively allosterically modulated by benzodiazepine binding, leading to a potentiated response to GABA. Diazepam (DZP, a benzodiazepine) is widely prescribed for anxiety, epileptic dis
Externí odkaz:
https://doaj.org/article/22c0615e4b604b4b81e1443b6dbc2ae5
Autor:
Tue G. Banke, Andres Barria
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
AMPA-type glutamate receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits and play important roles in synaptic transmission and plasticity. Here, we have investigated the development of AMPAR-mediated syn
Externí odkaz:
https://doaj.org/article/9fc5a03227e048c886a621ec2a4b7987
Autor:
Stephen D. Glasgow, Ryan McPhedrain, Jeanne F. Madranges, Timothy E. Kennedy, Edward S. Ruthazer
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
The numbers and strengths of synapses in the brain change throughout development, and even into adulthood, as synaptic inputs are added, eliminated, and refined in response to ongoing neural activity. A number of experimental techniques can assess th
Externí odkaz:
https://doaj.org/article/bf360d48f06c45e7b315eb424e84c7f4