Zobrazeno 1 - 10
of 192
pro vyhledávání: '"LTNP"'
Autor:
Samuel Kyobe, Grace Kisitu, Savannah Mwesigwa, John Farirai, Eric Katagirya, Gaone Retshabile, Lesedi Williams, Angela Mirembe, Lesego Ketumile, Misaki Wayengera, John Mukisa, Gaseene Sebetso, Thabo Diphoko, Marion Amujal, Edgar Kigozi, Fred Katabazi, Ronald Oceng, Busisiwe Mlotshwa, Koketso Morapedi, Betty Nsangi, Edward Wampande, Masego Tsimako, Chester Brown, Ishmael Kasvosve, Moses Joloba, Gabriel Anabwani, Sununguko Mpoloka, Graeme Mardon, Adeodata Kekitiinwa, Neil A. Hanchard, Jacqueline Kyosiimire–Lugemwa, Mogomotsi Matshaba, Dithan Kiragga
Publikováno v:
International Journal of Infectious Diseases, Vol 139, Iss , Pp 132-140 (2024)
Objectives: We utilize a large retrospective study cohort derived from electronic medical records to estimate the prevalence of long-term non-progression (LTNP) and determine the factors associated with progression among children infected with HIV in
Externí odkaz:
https://doaj.org/article/485968415239449bb3ea480de2a6ff4b
Autor:
Wanqi Ni, Li Ren, Lingjie Liao, Dan Li, Zhenwu Luo, Meiling Zhu, Ying Liu, Hui Xing, Zheng Wang, Yiming Shao
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundLong-term non-progressors (LTNPs) with HIV infection can naturally control viral replication for up to a decade without antiretroviral therapy (ART), but the underlying mechanisms of this phenomenon remain elusive.MethodsTo investigate the
Externí odkaz:
https://doaj.org/article/f90e944f580d41599f3d8d55169df326
Autor:
Ana Moyano, Oscar Blanch-Lombarte, Laura Tarancon-Diez, Nuria Pedreño-Lopez, Miguel Arenas, Tamara Alvaro, Concepción Casado, Isabel Olivares, Mar Vera, Carmen Rodriguez, Jorge del Romero, Cecilio López-Galíndez, Ezequiel Ruiz-Mateos, Julia G. Prado, María Pernas
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Long-Term Non-Progressors (LTNPs) are untreated Human Immunodeficiency virus type 1 (HIV-1) infected individuals able to control disease progression for prolonged periods. However, the LTNPs status is temporary, as viral load incr
Externí odkaz:
https://doaj.org/article/9781fb5c03ed4e0cb8b67f8ba4137e88
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
This article reviews the main discoveries achieved by transcriptomic approaches on HIV controller (HIC) and long-term non-progressor (LTNP) individuals, who are able to suppress HIV replication and maintain high CD4+ T cell levels, respectively, in t
Externí odkaz:
https://doaj.org/article/2e9393148f4141948c1b35206072760e
Autor:
Diogo Gama Caetano, Fernanda Heloise Côrtes, Gonzalo Bello, Suwellen Sardinha Dias de Azevedo, Brenda Hoagland, Larissa Melo Villela, Beatriz Grinsztejn, Valdiléa Gonçalves Veloso, Monick Lindenmeyer Guimarães, Mariza Gonçalves Morgado
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background HIV controllers (HICs) are a rare group of HIV-1-infected individuals able to naturally control viral replication. Several studies have identified the occurrence of HIV dual infections in seropositive individuals leading to diseas
Externí odkaz:
https://doaj.org/article/23287c72daa344aaa230ff2dd772ac2c
Akademický článek
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Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Abnormally increased immune activation is one of the main pathological features of acquired immunodeficiency syndrome (AIDS). This study aimed to determine whether long-term nonprogression (LTNP) suppresses the upregulation of imm
Externí odkaz:
https://doaj.org/article/8f055fdd55044c169dd66d63317f3fa6
Akademický článek
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Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background A small proportion of HIV-infected patients remain clinically and/or immunologically stable for years, including elite controllers (ECs) who have undetectable viremia (10 years). However, the mechanism of nonprogression needs to b
Externí odkaz:
https://doaj.org/article/f552ba4833934792af11a0c4906b7de8
Monocyte Based Correlates of Immune Activation and Viremia in HIV-Infected Long-Term Non-Progressors
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Disease progression monitoring through CD4 counts alone can be inadequate in HIV infection as ongoing immune activation may result in Serious non-AIDS events (SNAEs). SNAEs involve monocyte activation driven chronic inflammation with sign
Externí odkaz:
https://doaj.org/article/5f677d3ea81e4776afbffce11c84fb95